Catalog No.
FHE32810
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
ADCYAP1R1, PACAP-R-1, PACAP type I receptor, Pituitary adenylate cyclase-activating polypeptide type I receptor, PACAP-R1
Concentration
1.45 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P41586
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0130
Pituitary adenylyl cyclase activating polypeptide inhibits gli1 gene expression and proliferation in primary medulloblastoma derived tumorsphere cultures., PMID:21143927
Immunocytochemical identification of VPAC1, VPAC2, and PAC1 receptors in normal and neoplastic human tissues with subtype-specific antibodies., PMID:15623599
Distribution of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptors (VPAC1, VPAC2, and PAC1 receptor) in the rat brain., PMID:15282712
PAC1 and PACAP expression, signaling, and effect on the growth of HCT8, human colonic tumor cells., PMID:12409223
Expression of pituitary adenylate cyclase-activating polypeptide and PACAP type 1 receptor in the rat gastric and colonic myenteric neurons., PMID:11959368
Role of PACAP1 receptor in regulation of ECL cells and gastric acid secretion by pituitary adenylate cyclase activating peptide., PMID:11193828
Mice with markedly reduced PACAP (PAC(1)) receptor expression by targeted deletion of the signal peptide., PMID:11032869
Identification of an essential amino acid motif within the C terminus of the pituitary adenylate cyclase-activating polypeptide type I receptor that is critical for signal transduction but not for receptor internalization., PMID:10908567
Pituitary adenylate cyclase-activating polypeptide (PACAP), a neuron-derived peptide regulating glial glutamate transport and metabolism., PMID:10804201
PACAP type I receptor activation regulates ECL cells and gastric acid secretion., PMID:10562300
The pituitary adenylate cyclase activating polypeptide type 1 receptor (PAC1-R) is expressed on gastric ECL cells: evidence by immunocytochemistry and RT-PCR., PMID:9928007
For research use only. Not for human or drug use.
