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Anti-Human CD62L/SELL Antibody (Dreg-55)

Catalog #:   FHD03310 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG4
Applications: FCM, Neutralization
Accession: P14151
Overview

Catalog No.

FHD03310

Species reactivity

Human

Host species

Human

Isotype

IgG4

Clonality

Monoclonal

Conjugation

Unconjugated

Target

CD62 antigen-like family member L, Leukocyte adhesion molecule 1, CD62L, LYAM1, TQ1, SELL, Leukocyte-endothelial cell adhesion molecule 1, L-selectin, LAM-1, gp90-MEL, LNHR, LECAM1, Lymph node homing receptor, Leukocyte surface antigen Leu-8

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P14151

Applications

FCM, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Dreg-55

Data Image
  • Flow-cytometry
    Flow-cytometry using anti- human SELL antibody. Human Jurkat cell line were stained with an irrelevant antibody (Green Histogram) or an anti- human SELL antibody monoclonal antibody (Catalog # FHD03310 , Red Histogram) at a concentration of 20 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # PHB96441) and cells analysed on a NovoCyte Flow Cytometer.
References

In vivo labeling reveals that degranulation is increased under supraphysiological TCR stimulation, but not infection, in CD8+ T cells from old mice., PMID:40478430

Transcutaneous Imiquimod Combined With Anti-Programmed Cell Death-1 Monoclonal Antibody Extends the Survival of Mice Bearing Renal Cell Carcinoma., PMID:40371846

Identification and characterization of tissue resident memory T cells in malignant pleural effusions associated with non-small cell lung cancer., PMID:40285480

Oxaliplatin, ATR inhibitor and anti-PD-1 antibody combination therapy controls colon carcinoma growth, induces local and systemic changes in the immune compartment, and protects against tumor rechallenge in mice., PMID:40139833

Immune suppressive activities of low-density neutrophils in sepsis and potential use as a novel biomarker of sepsis-induced immune suppression., PMID:40108283

Bioorthogonal Chemical Engineering of rAAV Capsid: Advancing Gene Therapy Targeting Using Proteins., PMID:39992873

Flexible deformation and special interface structure in nanoparticle-stabilized Pickering bubbles strengthen the immunological response as adjuvant., PMID:39851034

Aging-induced immune microenvironment remodeling fosters melanoma in male mice via γδ17-Neutrophil-CD8 axis., PMID:39738047

Tocilizumab and immune signatures for targeted management of cytokine release syndrome in immune checkpoint therapy., PMID:39701282

Neutrophils in the Spotlight-An Analysis of Neutrophil Function and Phenotype in ARDS., PMID:39684262

An antibody against human interleukin-2 showing minimal binding to neonatal Fc receptor: Potent anti-tumor activity and reduced systemic toxicity in mice., PMID:39615864

Changes in Circulating CD44+CD62L- Treg Subsets and CD44-CD62L+ Treg Subsets Reflect the Clinical Status of Patients with Allergic Rhinitis., PMID:39226877

Elevated IL-15 levels in systemic lupus erythematosus: potential pathogenesis insight and therapeutic target., PMID:39217881

Immunogenicity of an Inactivated Senecavirus A Vaccine with a Contemporary Brazilian Strain in Mice., PMID:39203971

Overcoming immunotherapy resistance and inducing abscopal effects with boron neutron immunotherapy (B-NIT)., PMID:39119813

Mepolizumab depletes inflammatory but preserves homeostatic eosinophils in severe asthma., PMID:39115364

Anti-Cytokine Active Immunotherapy Based on Supramolecular Peptides for Alleviating IL-1β-Mediated Inflammation., PMID:39113323

The expression of PD-L1 on tumor-derived exosomes enhances infiltration and anti-tumor activity of αCD3 × αPD-L1 bispecific antibody-armed T cells., PMID:39105814

CD4+ and CD8+ T-cell multi-epitope chimeric protein associated with an MPLA adjuvant induce protective efficacy and long-term immunological memory for the immunoprophylaxis of American Tegumentary Leishmaniasis., PMID:39096765

Exhausted Lag-3+ CD4+ T cells are increased in pediatric Inflammatory Bowel Disease., PMID:39044534

Differential decline of SARS-CoV-2-specific antibody levels, innate and adaptive immune cells, and shift of Th1/inflammatory to Th2 serum cytokine levels long after first COVID-19., PMID:39003594

Immune cells phenotype and bioenergetic measures in CD4+ T cells differ between high and low feed efficient dairy cows., PMID:38987567

VNN2-expressing circulating monocytes exhibit unique functional characteristics and are decreased in patients with primary Sjögren's syndrome., PMID:38936146

Non-Glycosylated SARS-CoV-2 Omicron BA.5 Receptor Binding Domain (RBD) with a Native-like Conformation Induces a Robust Immune Response with Potent Neutralization in a Mouse Model., PMID:38893549

CD62-L down-regulation after L18-MDP stimulation as a complementary flow cytometry functional assay for the diagnosis of XIAP deficiency., PMID:38770762

Redirecting NK cells to the lymph nodes to augment their lymphoma-targeting capacity., PMID:38769377

CD4+CD57+ senescent T cells as promoters of systemic lupus erythematosus pathogenesis and the therapeutic potential of senolytic BCL-2 inhibitor., PMID:38752316

Boosting humoral and cellular immunity with enhanced STING activation by hierarchical mesoporous metal-organic framework adjuvants., PMID:38723671

Flow cytometric immunophenotypic differentiation patterns of bone marrow eosinophilopoiesis., PMID:38666394

Can sputum eosinophils predict a poor response to mepolizumab?, PMID:38663816

Exploring novel perspectives on eosinophilic inflammation in severe asthma., PMID:38623926

A whole blood-based functional assay to characterize immunoglobulin A effector functions., PMID:38616577

Activated sputum eosinophils associated with exacerbations in children on mepolizumab., PMID:38485057

rhIL-7-hyFc and hIL-2/TCB2c combination promotes an immune-stimulatory tumor microenvironment that improves antitumor efficacy of checkpoint inhibitors., PMID:38471713

Prevention of experimental autoimmune encephalomyelitis by targeting 6-sulfo sialyl Lewis X glycans involved in lymphocyte homing., PMID:38387051

Dynamics of Whole Transcriptome Analysis (WTA) and Surface markers expression (AbSeq) in Immune Cells of COVID-19 Patients and Recovered captured through Single Cell Genomics., PMID:38357647

[Establishment of a 21-color Panel for the Detection of Immune Cell Subsets 
in Human Non-small Cell Lung Cancer Tumor Tissues with Flow Cytometry]., PMID:38296626

Sequential engagement of adhesion molecules and cytokine receptors impacts both piecemeal and anaphylactic degranulation of human basophils., PMID:38226657

Immunoprotective effect and mechanism of rEg.P29 against CD4 + T cell-deficient mice with Echinococcus multilocularis infection., PMID:38151996

Prevention of Collagen-Induced Arthritis by an Anti-Glycan Monoclonal Antibody Reactive with 6-Sulfo Sialyl Lewis x in DBA/1 Mice., PMID:38064497

A self-assembled graphene oxide adjuvant induces both enhanced humoral and cellular immune responses in influenza vaccine., PMID:38036004

Circulating CD8+ T Cell Subsets in Primary Sjögren's Syndrome., PMID:37893153

Blood CD62Llow inflammatory eosinophils are related to the severity of asthma and reduced by mepolizumab., PMID:37792721

MiR-7 deficiency promotes Th1 polarization of CD4+T cells and enhances the antitumor effect in adoptive cell therapy for lung cancer., PMID:37755574

A novel monoclonal antibody against 6-sulfo sialyl Lewis x glycans attenuates murine allergic rhinitis by suppressing Th2 immune responses., PMID:37735247

Novel CSF biomarkers for diagnosis and integrated analysis of neuropsychiatric systemic lupus erythematosus: based on antibody profiling., PMID:37684700

Elevated Layilin-Positive Monocyte Levels in the Peripheral Blood of Patients with Systemic Lupus Erythematosus Reflect Their Autoimmune Status., PMID:37642473

Effects of direct-fed microbial supplementation on performance and immune parameters of lactating dairy cows., PMID:37641244

Functional characterization of small and large alveolar macrophages in sarcoidosis and idiopathic pulmonary fibrosis compared with non-fibrosis interstitial lung diseases., PMID:37574726

Analysis of Novel Immunological Biomarkers Related to Rheumatoid Arthritis Disease Severity., PMID:37569732

Datasheet
$ 165
Product specifications
50 μg 165 100 μg 272

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Anti-Human CD62L/SELL Antibody (Dreg-55) [FHD03310]
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