Please ensure Javascript is enabled for purposes of website accessibility
Home / Products / Super-Affinity Antibody

Anti-Human CD50/ICAM3 Antibody (SAA1382)

Catalog #:   FHE01710 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: FCM
Accession: P32942
Overview

Catalog No.

FHE01710

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Conjugation

Unconjugated

Target

CD50, CDw50, Intercellular adhesion molecule 3, ICAM-R, ICAM3, ICAM-3

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P32942

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1382

Data Image
  • Bioactivity
    Detects Human CD50/ICAM3 in indirect ELISAs.
  • Flow-cytometry
    Flow-cytometry using anti-human CD50 antibody.RPMI-8226 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD50 antibody monoclonal antibody (Catalog # FHE01710 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # PMB96441) and cells analysed on a NovoCyte Flow Cytometer.
  • Flow-cytometry
    Flow-cytometry using anti-human CD50 antibody.Human peripheral blood lymphocytes were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD50 antibody monoclonal antibody (Catalog # FHE01710 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # PMB96441) and cells analysed on a NovoCyte Flow Cytometer.
References

Comprehensive cell surface protein profiling of human mesenchymal stromal cells from peritoneal dialysis effluent and comparison with those from human bone marrow and adipose tissue., PMID:37603218

Unraveling the surface proteomic profile of multiple myeloma to reveal new immunotherapeutic targets and markers of drug resistance., PMID:36311892

An approach to chimeric subunit immunogen provides efficient protection against toxicity, type III and type v secretion systems of Shigella., PMID:34508943

Immunophenotypic Characterization and Purification of Neoplastic Cells from Lymph Nodes Involved by T-Cell/Histiocyte-rich Large B-cell Lymphoma by Flow Cytometry and Flow Cytometric Cell Sorting., PMID:31254446

Chitosan nano-structure loaded with recombinant E. coli O157:H7 antigens as a vaccine candidate can effectively increase immunization capacity., PMID:31240960

Transcriptomics and Immunological Analyses Reveal a Pro-Angiogenic and Anti-Inflammatory Phenotype for Decidual Endothelial Cells., PMID:30935090

ICAM3 mediates tumor metastasis via a LFA-1-ICAM3-ERM dependent manner., PMID:29729315

Bispecific chimeric antigen receptors targeting the CD4 binding site and high-mannose Glycans of gp120 optimized for anti-human immunodeficiency virus potency and breadth with minimal immunogenicity., PMID:29306566

Modulation of Proinflammatory Cytokines in Monocyte-Derived Dendritic Cells by Porcine Reproductive and Respiratory Syndrome Virus Through Interaction with the Porcine Intercellular-Adhesion-Molecule-3-Grabbing Nonintegrin., PMID:27643915

Characterization and expression of monoclonal antibody-defined molecules on resting and activated bovine αβ, γδ T and NK cells., PMID:26384699

Development and characterization of a monoclonal antibody specific for bovine CD209., PMID:25593043

An alternative micromethod to access the procoagulant activity of Bothrops jararaca venom and the efficacy of antivenom., PMID:25128708

Novel role of ICAM3 and LFA-1 in the clearance of apoptotic neutrophils by human macrophages., PMID:23775590

Fludarabine and cladribine induce changes in surface proteins on human B-lymphoid cell lines involved with apoptosis, cell survival, and antitumor immunity., PMID:22839105

Activated apoptotic cells induce dendritic cell maturation via engagement of Toll-like receptor 4 (TLR4), dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin (DC-SIGN), and β2 integrins., PMID:22396536

Apoptotic cell-derived ICAM-3 promotes both macrophage chemoattraction to and tethering of apoptotic cells., PMID:22117198

An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells., PMID:21841799

Adhesion molecules are promising candidates to establish surrogate markers for natalizumab treatment., PMID:20937631

A mechanistic rationale for combining alemtuzumab and rituximab in the treatment of ALL., PMID:20844239

Phenotyping studies of clonotypic B lymphocytes from patients with multiple myeloma by flow cytometry., PMID:19792049

Ovarian cancer-derived glycodelin impairs in vitro dendritic cell maturation., PMID:19609241

Intercellular adhesion molecule 1 (ICAM-1), but not ICAM-2 and -3, is important for dendritic cell-mediated human immunodeficiency virus type 1 transmission., PMID:19211748

Binding of the Streptococcus gordonii DL1 surface protein Hsa to the host cell membrane glycoproteins CD11b, CD43, and CD50., PMID:18678668

HIV transfer between CD4 T cells does not require LFA-1 binding to ICAM-1 and is governed by the interaction of HIV envelope glycoprotein with CD4., PMID:18377648

Glycosphingolipids in vascular endothelial cells: relationship of heterogeneity in Gb3Cer/CD77 receptor expression with differential Shiga toxin 1 cytotoxicity., PMID:18176841

Structural requirements for multimerization of the pathogen receptor dendritic cell-specific ICAM3-grabbing non-integrin (CD209) on the cell surface., PMID:18073208

Evaluation of in vivo and in vitro biological activity of a Vibrio cholerae 01 hemolysin., PMID:18053392

Use of flow cytometry to identify monoclonal antibodies that recognize conserved epitopes on orthologous leukocyte differentiation antigens in goats, llamas, and rabbits., PMID:17686528

Tonsil epithelial factors may influence oropharyngeal human immunodeficiency virus transmission., PMID:17620369

Mutation of a conserved asparagine in the I-like domain promotes constitutively active integrins alphaLbeta2 and alphaIIbbeta3., PMID:17468108

The role of complement regulatory proteins (CD55 and CD59) in the pathogenesis of autoimmune hemocytopenias., PMID:17289551

DC-SIGN binds ICAM-3 isolated from peripheral human leukocytes through Lewis x residues., PMID:17145745

Ligation of intercellular adhesion molecule 3 induces apoptosis of human blood eosinophils and neutrophils., PMID:17030234

Effect of a combination of extract from several plants on cell-mediated and humoral immunity of patients with advanced ovarian cancer., PMID:16619374

[Serum level of soluble forms of membranous antigens of immune system cells in carriers of virus hepatitis G markers]., PMID:16250593

[Linear and adhesive phenotype of tumor lymphocytes and clinical course of chronic leucosis]., PMID:15960204

Epitope mapping of monoclonal antibody to integrin alphaL beta2 hybrid domain suggests different requirements of affinity states for intercellular adhesion molecules (ICAM)-1 and ICAM-3 binding., PMID:15958383

Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin., PMID:15940144

Immunohistochemical study of cyclosporin-induced gingival overgrowth in renal transplant recipients., PMID:15732868

[Dynamics of the soluble CD50-antigen level in patients with breast cancer in the course of combined therapy]., PMID:15137202

ICAM-3 activation modulates cell-cell contacts of human bone marrow endothelial cells., PMID:14726630

Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses., PMID:12783086

The Prognosis of Survival in Patients with Some Solid Tumors Based on Optimal Partitions of Immunological Parameter Ranges., PMID:12687164

Functional antibodies to leukocyte adhesion molecules in antithymocyte globulins., PMID:12640305

Adhesion molecules as costimulators: ICAM-3 signaling potentiates CD3-mediated HIV-1 stimulation., PMID:12485933

Differential pathomechanisms of epidermal necrolytic blistering diseases., PMID:12429994

Immunophenotypic analysis of human spleen compartments., PMID:12392323

Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin (DC-SIGN, CD209), a C-type surface lectin in human DCs, is a receptor for Leishmania amastigotes., PMID:12122001

Functional evaluation of DC-SIGN monoclonal antibodies reveals DC-SIGN interactions with ICAM-3 do not promote human immunodeficiency virus type 1 transmission., PMID:12021323

Beta1 integrin triggering affects leukemic cell line sensitivity to natural killer cells., PMID:11941451

Datasheet
$ 198
Product specifications
50 μg 198 100 μg 328

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

Need help with your order?

Find out more about placing an order here

Anti-Human CD50/ICAM3 Antibody (SAA1382) [FHE01710]
Terms of sale Website terms of use Cookie policy Privacy
Copyright © 2025 AntibodySystem SAS. All Rights Reserved.            All Products are for Research Use Only