Catalog No.
FHD23410
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
Collagen receptor, ITGA2, VLA-2 subunit alpha, CD49B, CD49 antigen-like family member B, Platelet membrane glycoprotein Ia, GPIa, Integrin alpha-2, CD49b
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P17301
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0018
ST6GAL1 promotes IBD B cell recruitment to the inflamed colon in a CD22-dependent mechanism., PMID:40491026
Upregulation of Fcγ Receptor IV on Activated Monocytes and Macrophages Causes Nonspecific Binding of the PK136 Anti-NK1.1 Antibody in Murine Models of Toll-Like Receptor-Induced Inflammation., PMID:40275544
Management of a twin pregnancy patient with Glanzmann thrombasthenia might be caused by a novel ITGA2B gene mutation (c.2822G>A): a case report and family investigation., PMID:40126091
Novel GPIb-independent platelet aggregation induced by botrocetin: implications for diagnosis and antithrombotic therapy., PMID:39147240
A novel surface marker CD49d promotes TNF expression in oyster agranulocytes by mediating the MAPK pathway., PMID:38897309
Engagement of α3β1 and α2β1 integrins by hypervirulent Streptococcus agalactiae in invasion of polarized enterocytes., PMID:38511003
A Novel Polymer Nanoparticle Polydimethyl Diallyl Ammonium Chloride as An Adjuvant Enhances the Immune Response of SARS-CoV-2 Subunit Vaccine., PMID:38436662
Immunogenicity and protective efficacy of a trimeric full-length S protein subunit vaccine for porcine epidemic diarrhea virus., PMID:38220489
A novel PDPN antagonist peptide CY12-RP2 inhibits melanoma growth via Wnt/β-catenin and modulates the immune cells., PMID:38167452
Flow cytometric analysis of innate lymphoid cells: challenges and solutions., PMID:37809100
Comprehensive cell surface protein profiling of human mesenchymal stromal cells from peritoneal dialysis effluent and comparison with those from human bone marrow and adipose tissue., PMID:37603218
Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b., PMID:37311743
Cysteine carboxyethylation generates neoantigens to induce HLA-restricted autoimmunity., PMID:36927018
Filarial infections compromise influenza vaccination efficacy: Lessons from the mouse., PMID:36889363
A single F153Sβ3 mutation causes constitutive integrin αIIbβ3 activation in a variant form of Glanzmann thrombasthenia., PMID:36884296
Sialylated IVIg binding to DC-SIGN+ Hofbauer cells induces immune tolerance through the caveolin-1/NF-kB pathway and IL-10 secretion., PMID:36581222
Tolerance to 2,4-Dinitrofluorobenzene‒Induced Contact Hypersensitivity Is Mediated by CD73-Expressing Tissue-Homing Regulatory T Cells., PMID:36539031
Inhibitory effect of phenolic extract from squirting cucumber (Ecballium elaterium (L.) A. Rich) seed oil on integrin-mediated cell adhesion, migration and angiogenesis., PMID:36380921
Single and Multiplex Immunohistochemistry to Detect Platelets and Neutrophils in Rat and Porcine Tissues., PMID:36136817
CD49b Targeting Inhibits Tumor Growth and Boosts Anti-tumor Immunity., PMID:35860556
Adventitia-derived extracellular matrix hydrogel enhances contractility of human vasa vasorum-derived pericytes via α2 β1 integrin and TGFβ receptor., PMID:35770946
Streptococcus pneumoniae binds collagens and C1q via the SSURE repeats of the PfbB adhesin., PMID:35570359
TGF-β1 increases cellular invasion of colorectal neuroendocrine carcinoma cell line through partial epithelial-mesenchymal transition., PMID:35252596
Combination therapy with Nab-paclitaxel and the interleukin-15 fused with anti-human serum albumin nanobody as a synergistic treatment for colorectal cancer., PMID:35019820
FoxP3- Tr1 Cell in Generalized Myasthenia Gravis and Its Relationship With the Anti-AChR Antibody and Immunomodulatory Cytokines., PMID:34975721
Laminin Isoforms in Human Dental Pulp: Lymphatic Vessels Express Laminin-332, and Schwann Cell-Associated Laminin-211 Modulates CD163 Expression of M2-like Macrophages., PMID:34965967
The role of IP-10 and its receptor CXCR3 in early pregnancy., PMID:34655920
Platelets Independently Recruit into Asthmatic Lungs and Models of Allergic Inflammation via CCR3., PMID:33556295
Pharmacological HIF-1 stabilization promotes intestinal epithelial healing through regulation of α-integrin expression and function., PMID:33470153
A Potential Role of Adhesion Molecules on Lung Metastasis Enhanced by Local Inflammation., PMID:33109554
Staphylococcal superantigen-like 12 induces the production of interleukin 4 in murine basophils., PMID:32859377
Identification of Murine Basophils by Flow Cytometry and Histology., PMID:32766990
Screening of integrins localized on the surface of human epidermal melanocytes., PMID:32572848
Expression dynamics of integrin α2, α3, and αV upon osteogenic differentiation of human mesenchymal stem cells., PMID:32493499
Inhibition of neurogenic and thromboxane A2 -induced human prostate smooth muscle contraction by the integrin α2β1 inhibitor BTT-3033 and the integrin-linked kinase inhibitor Cpd22., PMID:32449814
A novel proangiogenic B cell subset is increased in cancer and chronic inflammation., PMID:32426497
Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes., PMID:32251437
Cryo-Electron Microscopy Structure of the αIIbβ3-Abciximab Complex., PMID:31969014
Increased Cell Detachment Ratio of Mesenchymal-Type Lung Cancer Cells on pH-Responsive Chitosan through the β3 Integrin., PMID:31771240
CD56+CD57+ infiltrates as the most predominant subset of intragraft natural killer cells in renal transplant biopsies with antibody-mediated rejection., PMID:31719573
Knock-in mice bearing constitutively active αIIb(R990W) mutation develop macrothrombocytopenia with severe platelet dysfunction., PMID:31691484
M. leprae interacts with the human epidermal keratinocytes, neonatal (HEKn) via the binding of laminin-5 with α-dystroglycan, integrin-β1, or -β4., PMID:31233498
Targeting Platelet GPVI Plus rt-PA Administration but Not α2β1-Mediated Collagen Binding Protects against Ischemic Brain Damage in Mice., PMID:31022936
ITGA2 as a potential nanotherapeutic target for glioblastoma., PMID:30996239
Impaired Contracture of 3D Collagen Constructs by Fibronectin-Deficient Murine Fibroblasts., PMID:30890950
Reversal of New Onset Type 1 Diabetes by Oral Salmonella-Based Combination Therapy and Mediated by Regulatory T-Cells in NOD Mice., PMID:30863412
Contribution of sialic acids to integrin α5β1 functioning in melanoma cells., PMID:30844664
VLA-2 blockade in vivo by vatelizumab induces CD4+FoxP3+ regulatory T cells., PMID:30783682
Role of Platelet Size Revisited-Function and Protein Composition of Large and Small Platelets., PMID:30727004
Downregulation of TREM-like transcript-1 and collagen receptor α2 subunit, two novel RUNX1-targets, contributes to platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia., PMID:30545930
For research use only. Not for human or drug use.
