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Anti-Human CD39/ENTPD1 Antibody (SRF367)

Catalog #:   FHE74010 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1, kappa
Applications: FCM
Accession: P49961
Overview

Catalog No.

FHE74010

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

Unconjugated

Target

Ecto-ATP diphosphohydrolase 1, NTPDase 1, ENTPD1, Ecto-ATPase 1, Ecto-apyrase, Ecto-ATPDase 1, Ectonucleoside triphosphate diphosphohydrolase 1, CD39, Lymphoid cell activation antigen

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P49961

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SRF367

Data Image
  • Flow-cytometry
    Flow-cytometry using anti-human CD39 antibody.CD39 Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD39 antibody monoclonal antibody (Catalog # FHE74010 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # PMB96441) and cells analysed on a NovoCyte Flow Cytometer.
References

Therapeutic potential of adenosine receptor modulators in cancer treatment., PMID:40530308

Frequency and stability of populations of CD4+ and CD4+CD25+Foxp3+CD127lo Treg in healthy adults defined by cytometry using monoclonal antibodies to T cell associated molecules., PMID:40464367

Assessment of CD73 activity in breast cancer-derived small extracellular vesicles: application to monitoring of patients' responses to immunotherapy., PMID:40390761

Identification and characterization of tissue resident memory T cells in malignant pleural effusions associated with non-small cell lung cancer., PMID:40285480

Adenosine-generating CD39+ plasmablasts predispose to successful infliximab therapy in pediatric IBD., PMID:40199584

Targeting Immune Checkpoint Inhibitors for Non-Small-Cell Lung Cancer: Beyond PD-1/PD-L1 Monoclonal Antibodies., PMID:40075753

Complement Activation and Hemolysis in Non-Human Primates Following Transfusion of Genetically Modified Pig Red Blood Cells., PMID:39933991

Blocking the CD39/CD73 pathway synergizes with anti-CD20 bispecific antibody in nodal B-cell lymphoma., PMID:39884778

Identification of B Cell Subpopulations with Pro- and Anti-Tumorigenic Properties in an Immunocompetent Mouse Model of Head and Neck Squamous Cell Carcinoma., PMID:39791721

Persistence of activated anti-mesothelin hYP218 chimeric antigen receptor T cells in the tumour is associated with efficacy in gastric and colorectal carcinomas., PMID:39548594

Perioperative sintilimab and neoadjuvant anlotinib plus chemotherapy for resectable non-small-cell lung cancer: a multicentre, open-label, single-arm, phase 2 trial (TD-NeoFOUR trial)., PMID:39465257

Allogenic MSC infusion in kidney transplantation recipients promotes within 4 hours distinct B cell and T cell phenotypes., PMID:39450174

Development of a CD39 nanobody and its enhancement to chimeric antigen receptor T cells efficacy against ovarian cancer in preclinical studies., PMID:39431011

Effects of two immunosuppression regimens on T-lymphocyte subsets in elderly kidney transplant recipients., PMID:39372414

Single-arm trial of neoadjuvant ipilimumab plus nivolumab with chemoradiotherapy in patients with resectable and borderline resectable lung cancer: the INCREASE study., PMID:39349061

Mitigation of checkpoint inhibitor-induced autoimmune hemolytic anemia through modulation of purinergic signaling., PMID:39102659

The immune landscape of the inflamed joint defined by spectral flow cytometry., PMID:39101538

The reduced frequency of CD39+CD73+ B cell subsets in SLE patients is correlated with disease activity., PMID:39094356

Causal relationship between immune cells and hepatocellular carcinoma: a Mendelian randomisation study., PMID:38947379

ADA/CD26 axis increases intra-tumor PD-1+CD28+CD8+ T-cell fitness and affects NSCLC prognosis and response to ICB., PMID:38915783

Characterization of AB598, a CD39 Enzymatic Inhibitory Antibody for the Treatment of Solid Tumors., PMID:38797955

CD200R activation on naïve T cells by B cells induces suppressive activity of T cells via IL-24., PMID:38780647

Adjuvant Pembrolizumab in Patients with Stage IIIA/N2 Non-Small Cell Lung Cancer Completely Resected after Neoadjuvant Concurrent Chemoradiation: A Prospective, Open-Label, Single-Arm, Phase 2 Trial., PMID:38697848

Generation and characterization of antagonistic anti-human CD39 nanobodies., PMID:38590528

Magnetic CAR T cell purification using an anti-G4S linker antibody., PMID:38574803

Gluten-Free Diet Induces Rapid Changes in Phenotype and Survival Properties of Gluten-Specific T Cells in Celiac Disease., PMID:38552723

Regulatory T cell-derived exosome mediated macrophages polarization for osteogenic differentiation in fracture repair., PMID:38508525

Epitope Mapping of an Anti-Mouse CD39 Monoclonal Antibody Using PA Scanning and RIEDL Scanning., PMID:38507671

CD44 expression on murine hepatic stellate cells promotes the induction of monocytic and polymorphonuclear myeloid-derived suppressor cells., PMID:38484149

The aged microenvironment impairs BCL6 and CD40L induction in CD4+ T follicular helper cell differentiation., PMID:38481058

rhIL-7-hyFc and hIL-2/TCB2c combination promotes an immune-stimulatory tumor microenvironment that improves antitumor efficacy of checkpoint inhibitors., PMID:38471713

Efficacy and safety of autologous tumor-infiltrating lymphocytes in recurrent or refractory ovarian cancer, colorectal cancer, and pancreatic ductal adenocarcinoma., PMID:38309721

[Establishment of a 21-color Panel for the Detection of Immune Cell Subsets 
in Human Non-small Cell Lung Cancer Tumor Tissues with Flow Cytometry]., PMID:38296626

In vitro B cell experiments explore the role of CD24, CD38, and energy metabolism in ME/CFS., PMID:38259473

Development of a Sensitive Anti-Mouse CD39 Monoclonal Antibody (C39Mab-1) for Flow Cytometry and Western Blot Analyses., PMID:38197855

[ARL67156, a small-molecule CD39 inhibitor, enhances natural killer cell cytotoxicity against gastric cancer cells in vitro and in nude mice]., PMID:38189385

A Rat Anti-Mouse CD39 Monoclonal Antibody for Flow Cytometry., PMID:38126892

Immune checkpoints are predominantly co-expressed by clonally expanded CD4+FoxP3+ intratumoral T-cells in primary human cancers., PMID:38057799

Leptin favors imbalance of antigen-specific CD4+ T-cells associated with severity of cat allergy., PMID:37954580

Exploring the Expression of Adenosine Pathway-Related Markers CD73 and CD39 in Colorectal and Pancreatic Carcinomas Characterized by Multiplex Immunofluorescence: A Pilot Study., PMID:37926083

Adenosine in cancer immunotherapy: Taking off on a new plane., PMID:37913941

Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization., PMID:37749499

Blinatumomab differentially modulates peripheral blood and bone marrow immune cell repertoire: A Campus ALL study., PMID:37700538

Proinflammatory allogeneic dendritic cells enhance the therapeutic efficacy of systemic anti-4-1BB treatment., PMID:37654492

Low Pretreatment CD4+:CD8+ T Cell Ratios and CD39+CD73+CD19+ B Cell Proportions Are Associated with Improved Relapse-Free Survival in Head and Neck Squamous Cell Carcinoma., PMID:37628721

Relationship between the Gene Expression of Adenosine Kinase Isoforms and the Expression of CD39 and CD73 Ectonucleotidases in Colorectal Cancer., PMID:37538807

BMPRII+ neural precursor cells isolated and characterized from organotypic neurospheres: an in vitro model of human fetal spinal cord development., PMID:37488910

Inhibitors of the CD73-adenosinergic checkpoint as promising combinatory agents for conventional and advanced cancer immunotherapy., PMID:37435071

Beyond CTLA-4 and PD-1 Inhibition: Novel Immune Checkpoint Molecules for Melanoma Treatment., PMID:37345056

Advances in CD73 inhibitors for immunotherapy: Antibodies, synthetic small molecule compounds, and natural compounds., PMID:37302340

Datasheet
$ 198
Product specifications
50 μg 198 100 μg 328

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For research use only. Not for human or drug use.

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Anti-Human CD39/ENTPD1 Antibody (SRF367) [FHE74010]
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