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Anti-Human CD28 Antibody (15E8#)

Catalog #:   FHC83420 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: FCM
Accession: P10747
Overview

Catalog No.

FHC83420

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Conjugation

Unconjugated

Target

CD28, TP44, T-cell-specific surface glycoprotein CD28

Concentration

1.65 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P10747

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

15E8#

Data Image
References

Diatom-Based Artificial Antigen-Presenting Cells: A Novel Approach for Adaptive Immune Modulation., PMID:40530806

CD28 and ICOS in immune regulation: Structural insights and therapeutic targeting., PMID:40527414

[Research on the inhibitory effects of evodiamine on activated T cell proliferation]., PMID:40525340

IL-33 Has a Protective Effect Against Perinatal Listeriosis by Regulating Mitophagy of CD8+ T Lymphocytes., PMID:40512525

From Molecular Precision to Clinical Practice: A Comprehensive Review of Bispecific and Trispecific Antibodies in Hematologic Malignancies., PMID:40508128

CTLA-4 blockade in ovarian cancer immunotherapy: Mechanisms and clinical strategies., PMID:40482550

Aptamers as therapeutic targets: prospects and progress in the treatment of cancers., PMID:40479828

The immunosuppressive effect of glucocorticoids in human primary T cells is mainly mediated via a rapid inhibition of the IL-2/IL-2R signaling axis., PMID:40468327

Effective CAR T-cell targeting of an MUC1 cleavage product., PMID:40447312

Ovalbumin-specific regulatory T cells differentiated from the naïve phenotype (CD44loCD62Lhi) in mesenteric lymph nodes stably suppress enteropathy even in severe food-allergic mice., PMID:40446078

Chimeric Autoantibody Receptor- and/or Peptide-MHC-Based CAR Therapies for Targeted Elimination of Antigen-Specific B or T Cells in Hypersensitivity Disorders Such as Allergies and Autoimmune Diseases., PMID:40422256

Biological and Clinical Relevance of Genetic Alterations in Peripheral T-cell Lymphomas., PMID:40416001

Tumor suppressing function of SLC16A7 in bladder cancer and its pan-cancer analysis., PMID:40410718

The Role of Abatacept on Inflammation and Fibrosis in Hypochlorous Acid-Induced Fibrosis Mice., PMID:40344312

PD-1 blockade employed at the time CD8+ T cells are activated enhances their antitumor efficacy., PMID:40341032

Unveiling the Role of Immune Cells and Plasma Metabolites in Breast Cancer Risk: A Mendelian Randomization and Mediation Analysis., PMID:40325806

Influence of polyfunctional Tbet+ T cells on specific clinical events in chronic lymphocytic leukaemia., PMID:40313965

Novel diagnostic biomarker and immune profiling of GPR56+ B cell subsets in systemic lupus erythematosus., PMID:40311320

Improvement in the function of self-activating chimeric antigen receptor by replacing the linker sequence., PMID:40308593

Treatment Efficacy and Molecular Dynamics of Neoadjuvant Durvalumab and Olaparib in Resectable Urothelial Bladder Cancer: The NEODURVARIB Trial., PMID:40298406

Peripheral T-cell subset activation in NMDAR encephalitis: Insights into pathogenesis and biomarker potential for disease monitoring., PMID:40288549

MUC18-Directed chimeric antigen receptor T cells for the treatment of mucosal melanoma., PMID:40275251

Activated blood-derived human primary T cells support replication of HAdV C5 and virus transmission to polarized human primary epithelial cells., PMID:40265914

Chimeric anti-HLA antibody receptor engineered human regulatory T cells suppress alloantigen-specific B cells from pre-sensitized transplant recipients., PMID:40236118

Transcriptomic signatures in peripheral CD4+T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation., PMID:40226614

Induction and Assessment of Activation in Rat Effector CD4+ Memory Th Cells., PMID:40220232

Expanding the CAR toolbox with high throughput screening strategies for CAR domain exploration: a comprehensive review., PMID:40210240

Recognition of different subsets of alloreactive T cells by activation-induced markers., PMID:40204006

Potency-optimized CD28-activating bispecific antibody for the targeted treatment of Nectin-4 positive cancers., PMID:40187750

Humanizing a CD28 signaling domain affects CD8 activation, exhaustion and stem-like precursors., PMID:40161835

Discovery of immunosuppressive secondary metabolites from Hypericum patulum., PMID:40146543

Anti-CD137 agonist antibody-independent and clinically feasible preparation of tumor-infiltrating lymphocytes from soft tissue sarcoma and osteosarcoma., PMID:40145091

LuQi formula ameliorates pressure overload-induced heart failure by regulating macrophages and regulatory T cells., PMID:40118747

Magnetic bead-sensitized optoporation coupled with antibodies-based activation for mRNA CAR-T cell manufacturing., PMID:40092640

Leveraging T cell co-stimulation for enhanced therapeutic efficacy of trispecific antibodies targeting prostate cancer., PMID:40081942

Targeting HER2-Positive Solid Tumors with CAR NK Cells: CD44 Expression Is a Critical Modulator of HER2-Specific CAR NK Cell Efficacy., PMID:40075578

Binding of RHOA G17V to p300 enhances its HAT activity: a new mechanism of epigenetic deregulation in TFH lymphoma., PMID:40020168

Composition and function of AChR chimeric autoantibody receptor T cells for antigen-specific B cell depletion in myasthenia gravis., PMID:40020066

Controlled activation modulates T-cell expansion and phenotype in stirred-tank bioreactors., PMID:40019461

Immunological biomarkers of response and resistance to treatment with cabozantinib and nivolumab in recurrent endometrial cancer., PMID:40010771

Peripheral blood CD8 + CD28+ T cells as predictive biomarkers for treatment response in metastatic colorectal cancer., PMID:39989261

Investigating T-Cell Receptor Dynamics Under In Vitro Antibody-Based Stimulation Using Imaging Flow Cytometry., PMID:39982013

Rheumatoid arthritis associated cytokines and therapeutics modulate immune checkpoint receptor expression on T cells., PMID:39981237

The CD64/CD28/CD3ζ chimeric receptor reprograms T-cell metabolism and promotes T-cell persistence and immune functions while triggering antibody-independent and antibody-dependent cytotoxicity., PMID:39962623

Immunophenotypical characterization of immune checkpoint receptor expression in cynomolgus monkeys and human healthy volunteers in resting and in T-cell stimulatory conditions in vitro., PMID:39945090

Recombinant CD80 fusion protein combined with discoidin domain receptor 1 inhibitor for cancer treatment., PMID:39918582

Proteogenomic Profiling Reveals Small ORFs and Functional Microproteins in Activated T Cells., PMID:39914663

Supplementation with heat-sterilized Lactobacillus crispatus strain KT-11 stimulates the T cell-related immune function of healthy Japanese adults: A pilot randomized, placebo-controlled, double-blind, parallel-group study., PMID:39889684

Immune mechanisms in multiple sclerosis: CD3 levels on CD28+ CD4+ T cells link antibody responses to human herpesvirus 6., PMID:39884183

Effect of cytotoxic CD8+ T-cells secretory proteins on hypoxic pancreatic cancer cells., PMID:39883638

Datasheet
$ 120
Product specifications
50 μg 120 100 μg 198

Contact Information

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For research use only. Not for human or drug use.

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Anti-Human CD28 Antibody (15E8#) [FHC83420]
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