Catalog No.
FHJ85320
Species reactivity
Human
Host species
Human
Isotype
IgG4, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
BAFF, ZTNF4, BLYS, Tumor necrosis factor ligand superfamily member 13B, Dendritic cell-derived TNF-like molecule, TALL-1, TNF- and APOL-related leukocyte expressed ligand 1, BLyS, B lymphocyte stimulator, TNFSF13B, CD257, TNFSF20, TALL1, B-cell-activating factor,Neutrokine-alpha
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9Y275
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0081
FCRL1 and BAFF mRNA Expression as Novel Diagnostic and Prognostic Biomarkers in Diffuse Large B-Cell Lymphoma: Expression Signatures Predict R-CHOP Therapy Response and Survival., PMID:39941037
Development and therapeutic assessment of bispecific nanobodies targeting B-cell activating factor and interleukin-17 for the neutralization of inflammatory mediators in autoimmune diseases., PMID:39870268
A first-in-human, randomized study of the safety, pharmacokinetics and pharmacodynamics of povetacicept, an enhanced dual BAFF/APRIL antagonist, in healthy adults., PMID:39494621
Venetoclax dose escalation rapidly activates a BAFF/BCL-2 survival axis in chronic lymphocytic leukemia., PMID:39471335
B-Cell Maturation Antigen (BCMA) as a Biomarker and Potential Treatment Target in Systemic Lupus Erythematosus., PMID:39409173
Current status of BAFF targeting immunotherapy in B-cell neoplasm., PMID:39222149
Serum BAFF levels are associated with the prognosis of idiopathic membranous nephropathy., PMID:39143819
Changes in peripheral blood IL-9, Th9, and BAFF levels in patients with allergic rhinitis and their clinical implications., PMID:39093090
B Cell-activating factor (BAFF): A promising trans-nosographic biomarker of inflammation and autoimmunity in bipolar disorder and schizophrenia., PMID:39047848
Proof-of-concept study evaluating humoral primary immunodeficiencies via CJ:KREC ratio and serum BAFF level., PMID:38906917
Bronchiectasis, lymphadenopathies related to BAFF overexpression and lymphoplasmacytic cystitis as adverse events associated with prolonged use of rituximab in systemic autoimmune rheumatic diseases., PMID:38849075
Association of B-cell activating factor gene variants with serum anti-JCV antibody positivity in male patients with multiple sclerosis under natalizumab treatment: Implications for progressive multifocal leukoencephalopathy risk stratification., PMID:38761670
B cell-activating factor is involved in thrombocytopenia in patients with liver cirrhosis., PMID:36098792
Protein and functional isoform levels and genetic variants of the BAFF and APRIL pathway components in systemic lupus erythematosus., PMID:35780200
Serum Soluble B Cell-Activating Factor Is a Non-Invasive Biomarker of Antibody-Mediated Rejection in Kidney Allograft With Satisfactory Risk Stratification Performance But Negligible Diagnostic Value., PMID:35493478
Analysis of TNFSF13B polymorphisms and BAFF expression in rheumatoid arthritis and primary Sjögren's syndrome patients., PMID:35411715
BAFF rs9514828 gene polymorphism and the risk of the development of inhibitors in children with severe haemophilia A., PMID:35316553
Increased gene expression of B cell-activating factor of tumor necrosis factor family, in remitting antineutrophil cytoplasmic antibody-associated vasculitis patients., PMID:34908244
BAFF Attenuates Immunosuppressive Monocytes in the Melanoma Tumor Microenvironment., PMID:34810198
Possible interplay between estrogen and the BAFF may modify thyroid activity in Graves' disease., PMID:34725405
Fecal Microbiota Transplantation Modulates Renal Phenotype in the Humanized Mouse Model of IgA Nephropathy., PMID:34712223
B Cell-Activating Factor Antagonism Attenuates the Growth of Experimental Abdominal Aortic Aneurysm., PMID:34509440
High B-cell activating factor levels in multi-transfused thalassemia patients., PMID:34396626
B-cell activating factor BAFF as a novel alert marker for the immunological risk stratification after kidney transplantation., PMID:34373996
BAFF receptor polymorphisms and deficiency in humans., PMID:34311146
Keeping up with the stress of antibody production: BAFF and APRIL maintain memory plasma cells., PMID:34303157
10 Years of belimumab experience: What have we learnt?, PMID:34238087
Expansion of inflammatory monocytes in periphery and infiltrated into thyroid tissue in Graves' disease., PMID:34188092
Function, occurrence and inhibition of different forms of BAFF., PMID:34182216
Meant to B: B cells as a therapeutic target in systemic lupus erythematosus., PMID:34128474
BAFF predicts immunogenicity in older patients with rheumatoid arthritis treated with TNF inhibitors., PMID:34079038
BAFF, APRIL and BAFFR on the pathogenesis of Immunoglobulin-A vasculitis., PMID:34075170
Modifications of the BAFF/BAFF-Receptor Axis in Patients With Pemphigus Treated With Rituximab Versus Standard Corticosteroid Regimen., PMID:34054835
The role of BAFF and G-CSF for rituximab-induced late-onset neutropenia (LON) in lymphomas., PMID:34003398
Investigating the Role of BAFF and Its Receptors in Renal Transplant Recipients with Chronic Antibody-Mediated Rejection., PMID:33748289
Serum markers of B-cell activation in pregnant women with atopic asthma., PMID:33682259
B cell-activating factor modulates the factor VIII immune response in hemophilia A., PMID:33651716
FcγRIIb Expression Is Decreased on Naive and Marginal Zone-Like B Cells From Females With Multiple Sclerosis., PMID:33505402
BAFF, involved in B cell activation through the NF-κB pathway, is related to disease activity and bone destruction in rheumatoid arthritis., PMID:33483588
A longitudinal study of plasma BAFF levels in mothers and their infants in Uganda, and correlations with subsets of B cells., PMID:33465125
B-cell activating factor (BAFF) expression is associated with Crohn's disease and can serve as a potential prognostic indicator of disease response to Infliximab treatment., PMID:33339749
Evolutionarily Selected Overexpression of the Cytokine BAFF Enhances Mucosal Immune Response Against P. falciparum., PMID:33123155
Artesunate inhibits Sjögren's syndrome-like autoimmune responses and BAFF-induced B cell hyperactivation via TRAF6-mediated NF-κB signaling., PMID:33086170
The BAFF / APRIL system as therapeutic target in multiple sclerosis., PMID:32900236
Anti-Ro52 Autoantibodies Are Related to Chronic Graft-vs.-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation., PMID:32849514
CD40- and CD95-specific antibody single chain-Baff fusion proteins display BaffR-, TACI- and BCMA-restricted agonism., PMID:32840410
Effects of BAFF Neutralization on Atherosclerosis Associated With Systemic Lupus Erythematosus., PMID:32783382
Associations Between Smoking and Systemic Lupus Erythematosus-Related Cytokines and Chemokines Among US Female Nurses., PMID:32619290
The roles of B cell activation factor (BAFF) and a proliferation-inducing ligand (APRIL) in allergic asthma., PMID:32522667
Expression of BAFF and BAFF receptors in primary Sjögren's syndrome patients with ectopic germinal center-like structures., PMID:32506205
For research use only. Not for human or drug use.
