Anti-Human CD1d Antibody (402.8#)

Catalog No.

FHD12910

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

Unconjugated

Target

CD1d, CD1D, Antigen-presenting glycoprotein CD1d, R3G1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P15813

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

402.8#

B cell-expressed CD1d promotes MPL/TDCM lipid emulsion adjuvant effects in polysaccharide vaccines., PMID:40280183

The balance between conventional and unconventional T follicular helper cells influences autoreactive B cell responses., PMID:40252220

Can invariant Natural Killer T cells drive B cell fate? a look at the humoral response., PMID:40040714

Amine headgroups in ionizable lipids drive immune responses to lipid nanoparticles by binding to the receptors TLR4 and CD1d., PMID:39363106

Over-activation of iNKT cells aggravate lung injury in bronchopulmonary dysplasia mice., PMID:39342744

TIPE2 protein restrains invariant NKT activation and protects against immune-mediated hepatitis in mice., PMID:39325944

NKT cells promote Th1 immune bias to dengue virus that governs long-term protective antibody dynamics., PMID:39088280

Immune phenotyping in a pediatric multicenter transplant study: Suitability of a preformulated dry-antibody panel system., PMID:39013208

A Glycolipid-Peptide-Hapten Tricomponent Conjugate Vaccine Generates Durable Antihapten Antibody Responses in Mice., PMID:38829263

Studying the cellular basis of small bowel enteropathy using high-parameter flow cytometry in mouse models of primary antibody deficiency., PMID:38803492

Immunotherapy with an antibody against CD1d modulates neuroinflammation in an α-synuclein transgenic model of Lewy body like disease., PMID:38622654

Role of Natural Killer T (NKT) Cells in Myeloma Biology and Therapy., PMID:38421714

Studying the cellular basis of small bowel enteropathy using high-parameter flow cytometry in mouse models of primary antibody deficiency., PMID:38352330

Anti-Vα24Jα18 TCR Antibody Tunes iNKT Cell Responses to Target and Kill CD1d-negative Tumors in an FcγRII (CD32)-dependent Manner., PMID:38319156

Conformationally Restricted Analogues of α-Galactosylceramide as Adjuvant in COVID-19 Subunit Vaccine., PMID:38116441

Enhanced CD1d phosphatidylserine presentation using a single-domain antibody promotes immunomodulatory CD1d-TIM-3 interactions., PMID:38040419

CD1d-dependent neuroinflammation impairs tissue repair and functional recovery following a spinal cord injury., PMID:37905092

Diversification of a Novel α-Galactosyl Ceramide Hotspot Boosts the Adjuvant Properties in Parenteral and Mucosal Vaccines., PMID:37857582

Extended interval dosing of ocrelizumab modifies the repopulation of B cells without altering the clinical efficacy in multiple sclerosis., PMID:37752582

Anti-Glycolipid Antibody Examination in Five EAE Models and Theiler's Virus Model of Multiple Sclerosis: Detection of Anti-GM1, GM3, GM4, and Sulfatide Antibodies in Relapsing-Remitting EAE., PMID:37629117

CD1d facilitates African swine fever virus entry into the host cells via clathrin-mediated endocytosis., PMID:37254454

CD1d-dependent natural killer T-cells inactivation aggravates sepsis-induced myocardial injury via T lymphocytes infiltration and IL-6 production in mice., PMID:37182446

Towards a better understanding of human iNKT cell subpopulations for improved clinical outcomes., PMID:37153585

THE IL-33/ST2 AXIS PROMOTES ACUTE RESPIRATORY DISTRESS SYNDROME BY NATURAL KILLER T CELLS., PMID:36870074

A bispecific T cell engager recruits both type 1 NKT and Vγ9Vδ2-T cells for the treatment of CD1d-expressing hematological malignancies., PMID:36868236

Fully synthetic Tn-based three-component cancer vaccine using covalently linked TLR4 ligand MPLA and iNKT cell agonist KRN-7000 as built-in adjuvant effectively protects mice from tumor development., PMID:36561989

Activation of cDCs and iNKT cells contributes to triptolide-induced hepatotoxicity via STING signaling pathway and endoplasmic reticulum stress., PMID:36520315

Demonstration of the Antitumor Activity of the iNKT Agonist ABX196, a Novel Enhancer of Cancer Immunotherapy, in Melanoma and Hepatocarcinoma Mouse Models., PMID:36198025

Stimulation of naïve B cells with a fusion protein consisting of FlaA and Bet v 1 induces regulatory B cells ex vivo., PMID:36196479

3D structures inferred from cDNA clones identify the CD1D-Restricted γδ T cell receptor in dromedaries., PMID:36016959

C-type lectin Mincle-dependent and -independent activation of invariant NKT cells by exposure to Helicobacter pylori α-cholesteryl glucosides., PMID:35920835

Human iNKT Cells Modulate Macrophage Survival and Phenotype., PMID:35885028

Synthesis and Immunological Activity of Novel Oligo(ethylene glycol) Analogues of α-Galactosylceramide., PMID:35785299

IL-17A produced by invariant natural killer T cells and CD3+ CD56+ αGalcer-CD1d tetramer- T cells promote liver fibrosis in patients with primary biliary cholangitis., PMID:35730799

A single immunization with cellular vaccine confers dual protection against SARS-CoV-2 and cancer., PMID:35598170

Splenic B1 B Cells Acquire a Proliferative and Anti-Inflamatory Profile During Pregnancy in Mice., PMID:35572585

Homeostatic serum IgE is secreted by plasma cells in the thymus and enhances mast cell survival., PMID:35301301

Immunomodulatory potential of in vivo natural killer T (NKT) activation by NKTT320 in Mauritian-origin cynomolgus macaques., PMID:35243248

iNKT cells can effectively inhibit IL-6 production by B cells in systemic sclerosis., PMID:35181242

The Alteration of Circulating Lymphocyte Subsets During Tacrolimus Therapy in Neuromyelitis Optica Spectrum Disorder and Its Correlation With Clinical Outcomes., PMID:35126303

Single-cell transcriptome profiling and the use of AID deficient mice reveal that B cell activation combined with antibody class switch recombination and somatic hypermutation do not benefit the control of experimental trypanosomosis., PMID:34762705

Activation of iNKT Cells Facilitates Liver Repair After Hepatic Ischemia Reperfusion Injury Through Acceleration of Macrophage Polarization., PMID:34691073

Redirecting iNKT Cell Antitumor Immunity with α-GalCer/CD1d-scFv Fusion Proteins., PMID:34524672

Detection of Mouse Type I NKT (iNKT) Cells by Flow Cytometry., PMID:34524664

α-Galactosylceramide-Reactive NKT Cells Increase IgG1 Class Switch against a Clostridioides difficile Polysaccharide Antigen and Enhance Immunity against a Live Pathogen Challenge., PMID:34424751

The lysophospholipid-binding molecule CD1D is not required for the alloimmunization response to fresh or stored RBCs in mice despite RBC storage driving alterations in lysophospholipids., PMID:34181769

Checkpoint blockade accelerates a novel switch from an NKT-driven TNFα response toward a T cell driven IFN-γ response within the tumor microenvironment., PMID:34135102

Effects of Peptide-Induced Immune Tolerance on Murine Lupus., PMID:34093553

Glycolipid-Containing Nanoparticle Vaccine Engages Invariant NKT Cells to Enhance Humoral Protection against Systemic Bacterial Infection but Abrogates T-Independent Vaccine Responses., PMID:33811104

NK1.1- natural killer T cells upregulate interleukin-17 expression in experimental lupus nephritis., PMID:33719574

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