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Anti-Human CD180 Antibody (G28-8)

Catalog #:   FHJ43610 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1, kappa
Applications: FCM
Accession: Q99467
Overview

Catalog No.

FHJ43610

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

Unconjugated

Target

Radioprotective 105 kDa protein, Lymphocyte antigen 64, RP105, LY64, CD180 antigen, CD180

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q99467

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

G28-8

Data Image
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Disturbed Complement Receptor Expression Pattern of B Cells Is Enhanced by Toll-like Receptor CD180 Ligation in Diffuse Cutaneous Systemic Sclerosis., PMID:39273179

Toll-like Receptor Homologue CD180 Ligation of B Cells Upregulates Type I IFN Signature in Diffuse Cutaneous Systemic Sclerosis., PMID:39063175

Irradiation Attenuates Systemic Lupus Erythematosus-Like Morbidity in NZBWF1 Mice: Focusing on CD180-Negative Cells., PMID:37886369

Ligation of TLR Homologue CD180 of B Cells Activates the PI3K/Akt/mTOR Pathway in Systemic Sclerosis and Induces a Pathological Shift in the Expression of BAFF Receptors., PMID:35743222

High-Dimensional Analysis Reveals Distinct Endotypes in Patients With Idiopathic Inflammatory Myopathies., PMID:35371068

Single-cell RNA-Seq reveals transcriptional heterogeneity and immune subtypes associated with disease activity in human myasthenia gravis., PMID:34521820

Toll-Like Receptor Homolog CD180 Expression Is Diminished on Natural Autoantibody-Producing B Cells of Patients with Autoimmune CNS Disorders., PMID:34124274

A new score including CD43 and CD180: Increased diagnostic value for atypical chronic lymphocytic leukemia., PMID:34061467

A Novel Gene Delivery Vector of Agonistic Anti-Radioprotective 105 Expressed on Cell Membranes Shows Adjuvant Effect for DNA Immunization Against Influenza., PMID:33414788

B cell targeting by molecular adjuvants for enhanced immunogenicity., PMID:33252273

Toll-Like Receptor Mediated Activation of Natural Autoantibody Producing B Cell Subpopulations in an Autoimmune Disease Model., PMID:31817576

Ligation of CD180 contributes to endotoxic shock by regulating the accumulation and immunosuppressive activity of myeloid-derived suppressor cells through STAT3., PMID:30557700

CD180 Ligation Inhibits TLR7- and TLR9-Mediated Activation of Macrophages and Dendritic Cells Through the Lyn-SHP-1/2 Axis in Murine Lupus., PMID:30498494

Canine leishmaniasis: Genome-wide analysis and antibody response to Lutzomyia longipalpis saliva., PMID:29742167

Myeloma Cells Are Activated in Bone Marrow Microenvironment by the CD180/MD-1 Complex, Which Senses Lipopolysaccharide., PMID:29363546

Protection of mice deficient in mature B cells from West Nile virus infection by passive and active immunization., PMID:29176765

PHAGOCYTOSIS AND EXPRESSION OF FCg-RECEPTORS AND CD180 ON MONOCYTES IN CHRONIC LYMPHOCYTIC LEUKEMIA., PMID:28972490

3LPS-binding protein and its interactions with P. gingivalis LPS modulate pro-inflammatory response and Toll-like receptor signaling in human oral keratinocytes., PMID:28384159

Discordant frequencies of tissue-resident and circulating CD180-negative B cells in chronic rhinosinusitis., PMID:28236375

Proteomic profile of circulating immune complexes in chronic Chagas disease., PMID:27223052

Human CD180 Transmits Signals via the PIM-1L Kinase., PMID:26555723

Down-regulation of B cell-related genes in peripheral blood leukocytes of Parkinson's disease patients with and without GBA mutations., PMID:26410072

Ligation of CD180 inhibits IFN-α signaling in a Lyn-PI3K-BTK-dependent manner in B cells., PMID:26277892

IRF4 Is a Critical Gene in Retinoic Acid-Mediated Plasma Cell Formation and Is Deregulated in Common Variable Immunodeficiency-Derived B Cells., PMID:26276871

Correlation of the expression of CD32 and CD180 receptors on CLL cells and MEC1 cell line., PMID:25879560

Aberrant expression of Fcγ-receptors and Toll like receptor CD180 on monocytes from patients with chronic lymphocytic leukaemia., PMID:25802446

Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy., PMID:25749095

Rewiring of sIgM-Mediated Intracellular Signaling through the CD180 Toll-like Receptor., PMID:25611435

B-cell inhibition by cross-linking CD79b is superior to B-cell depletion with anti-CD20 antibodies in treating murine collagen-induced arthritis., PMID:25471597

Cell surface phenotype profiles distinguish stable and progressive chronic lymphocytic leukemia., PMID:24289109

An unexpected intriguing effect of Toll-like receptor regulator RP105 (CD180) on atherosclerosis formation with alterations on B-cell activation., PMID:24115036

Targeting antigens to CD180 rapidly induces antigen-specific IgG, affinity maturation, and immunological memory., PMID:24019553

Retinoic acid improves defective TLR9/RP105-induced immune responses in common variable immunodeficiency-derived B cells., PMID:24006462

TLR9-signaling is required for turning retinoic acid into a potent stimulator of RP105 (CD180)-mediated proliferation and IgG synthesis in human memory B cells., PMID:23103284

The anti-inflammatory actions of IL-4 in human monocytes are not mediated by IL-10, RP105 or the kinase activity of RIPK2., PMID:22484241

Pathogenesis of lupus-like nephritis through autoimmune antibody produced by CD180-negative B lymphocytes in NZBWF1 mouse., PMID:22387632

[BCMA and autoantibody-producing RP105 B cells; possible new targets of B cell therapy in systemic lupus erythematosus]., PMID:22374441

RP105-negative B cells in systemic lupus erythematosus., PMID:21941580

Anti-CD180 (RP105) activates B cells to rapidly produce polyclonal Ig via a T cell and MyD88-independent pathway., PMID:21918197

CD180 functions in activation, survival and cycling of B chronic lymphocytic leukaemia cells., PMID:21443749

Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica., PMID:21321193

Potentiation of TLR9 responses for human naïve B-cell growth through RP105 signaling., PMID:20133206

Antibody-drug conjugates for the treatment of non-Hodgkin's lymphoma: target and linker-drug selection., PMID:19258515

Resting human memory B cells are intrinsically programmed for enhanced survival and responsiveness to diverse stimuli compared to naive B cells., PMID:19124732

Increase of RP105-lacking activated B cells in the peripheral blood and salivary glands in patients with Sjögren's syndrome., PMID:18328140

Altered expression of TLR homolog RP105 on monocytes hypersensitive to LPS in patients with primary biliary cirrhosis., PMID:17448566

Analysis of components of the CD14/TLR system on leukocytes of patients with atopic dermatitis., PMID:17284926

Differential expression of CD 180 and IgM by B-cell chronic lymphocytic leukaemia cells using mutated and unmutated immunoglobulin VH genes., PMID:16225650

Vav proteins are required for B-lymphocyte responses to LPS., PMID:15811961

Two cases of antinuclear antibody negative lupus showing increased proportion of B cells lacking RP105., PMID:15742454

Datasheet
$ 225
Product specifications
50 μg 225 100 μg 372

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For research use only. Not for human or drug use.

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Anti-Human CD180 Antibody (G28-8) [FHJ43610]
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