Catalog No.
FHE54320
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
Receptor-binding FasL ectodomain, APL, APT1LG1, FasL ICD, Fas antigen ligand, CD178, sFasL, CD95L, APTL, TNFSF6, Apoptosis antigen ligand, SPA, FASLG, FasL, SPPL2A-processed FasL form, Tumor necrosis factor ligand superfamily member 6, Soluble Fas ligand, Fas ligand, CD95 ligand, CD95-L, FASL
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P48023
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
NOK1/NOK-1
A Novel Tetravalent CD95/Fas Fusion Protein With Superior CD95L/FasL Antagonism., PMID:39219154
Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies., PMID:35013338
CAR-NK Cells: From Natural Basis to Design for Kill., PMID:34970253
Immune response to intravenous immunoglobulin in patients with Kawasaki disease and MIS-C., PMID:34464357
Cord blood soluble Fas ligand linked to allergic rhinitis and lung function in seven-year-old children., PMID:33879403
Glycolysis and Oxidative Phosphorylation Play Critical Roles in Natural Killer Cell Receptor-Mediated Natural Killer Cell Functions., PMID:32153568
Effects of 5-FU and anti-EGFR antibody in combination with ASA on the spherical culture system of HCT116 and HT29 colorectal cancer cell lines., PMID:31180528
Killing of Latently HIV-Infected CD4 T Cells by Autologous CD8 T Cells Is Modulated by Nef., PMID:30254642
ADAM15 in Apoptosis Resistance of Synovial Fibroblasts: Converting Fas/CD95 Death Signals Into the Activation of Prosurvival Pathways by Calmodulin Recruitment., PMID:30003689
Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation., PMID:29889098
Early activation of CD95 is limited and localized to the cytotoxic synapse., PMID:29797791
Fas/FasL interaction mediates imbalanced cytokine/cytotoxicity responses of iNKT cells against Jurkat cells., PMID:29783159
Curcumin enhances the anti-cancer effects of Paris Saponin II in lung cancer cells., PMID:29608021
Magnetic nanoparticle-mediated gene therapy to induce Fas apoptosis pathway in breast cancer., PMID:29593359
Inhibition of CD95/CD95L (FAS/FASLG) Signaling with APG101 Prevents Invasion and Enhances Radiation Therapy for Glioblastoma., PMID:29453321
Induction of apoptosis in breast cancer cells in vitro by Fas ligand reverse signaling., PMID:29185091
Immunohistochemical Analysis of the Extrinsic Apoptosis Process in the Non-Neoplastic and Neoplastic Prostate., PMID:28984341
Genetic polymorphisms predict response to anti-tumor necrosis factor treatment in Crohn's disease., PMID:28785150
FasR and FasL in colorectal cancer., PMID:28766682
DcR3 promotes hepatoma cell migration by downregulating E-cadherin expression., PMID:28560426
Lithium enhances the antitumour effect of temozolomide against TP53 wild-type glioblastoma cells via NFAT1/FasL signalling., PMID:28359080
B-cells with a FasL expressing regulatory phenotype are induced following successful anti-tuberculosis treatment., PMID:28250925
Review of Toxic Epidermal Necrolysis., PMID:27999358
Rituximab response in follicular lymphoma is associated with the rs20575 polymorphism in TRAILR1 extrinsic apoptosis trigger., PMID:27977511
Regulation of Intrinsic and Extrinsic Apoptotic Pathways in Osteosarcoma Cells Following Oleandrin Treatment., PMID:27886059
Bifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces FasL and TNFR2 mediated antitumor apoptosis in solid tumors., PMID:27464624
A polymorphism in FASL is associated with rituximab response in follicular lymphoma patients., PMID:26950187
T lymphocytes engineered to express a CD16-chimeric antigen receptor redirect T-cell immune responses against immunoglobulin G-opsonized target cells., PMID:26705740
RANKL/RANK interaction promotes the growth of cervical cancer cells by strengthening the dialogue between cervical cancer cells and regulation of IL-8 secretion., PMID:26398902
Enhancing the antitumor efficacy of a cell-surface death ligand by covalent membrane display., PMID:25902490
BIN1 tumor suppressor regulates Fas/Fas ligand-mediated apoptosis through c-FLIP in cutaneous T-cell lymphoma., PMID:25578476
Enhancing the bystander killing effect of an oncolytic HSV by arming it with a secretable apoptosis activator., PMID:25567538
Hepatitis B virus core protein inhibits Fas-mediated apoptosis of hepatoma cells via regulation of mFas/FasL and sFas expression., PMID:25466893
Radiation-induced glioblastoma signaling cascade regulates viability, apoptosis and differentiation of neural stem cells (NSC)., PMID:25273222
Immunomodulation due to plasma or plasma-platelet apheresis donation: Events occurring during donation procedures., PMID:25266338
[Natural killer cell cytotoxic activity in critical pediatric patients with suspected hemophagocytic syndrome]., PMID:25081072
Plasmacytoid dendritic cells mediate synergistic effects of HIV and lipopolysaccharide on CD27+ IgD- memory B cell apoptosis., PMID:25056888
CD8+HLA-DR+ T cells are increased in patients with severe aplastic anemia., PMID:24969051
Fas/FasL in the immune pathogenesis of severe aplastic anemia., PMID:24938700
Protection of neuronal cell death against diabetes-induced apoptosis by Fas blocker ZB4., PMID:24874011
Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors., PMID:24793239
Infection with respiratory syncytial virus influences FasL-mediated apoptosis of pulmonary γδ T cells in a murine model of allergen sensitization., PMID:24564286
Role of Fas/FasL pathway-mediated alveolar macrophages releasing inflammatory cytokines in human silicosis., PMID:24331540
Extra cellular matrix derived metabolite regulates angiogenesis by FasL mediated apoptosis., PMID:24324608
Differential protein-protein interactions of full length human FasL and FasL fragments generated by proteolysis., PMID:24291222
Epstein-Barr Virus_Encoded LMP1 upregulates microRNA-21 to promote the resistance of nasopharyngeal carcinoma cells to cisplatin-induced Apoptosis by suppressing PDCD4 and Fas-L., PMID:24194922
CD80 (B7.1) and CD86 (B7.2) induce EBV-transformed B cell apoptosis through the Fas/FasL pathway., PMID:24008628
CD95 (FAS) and CD178 (FASL) induce the apoptosis of CD4+ and CD8+ cells isolated from the peripheral blood and spleen of dogs naturally infected with Leishmania spp., PMID:23920055
[Pro-apoptotic effects of curcumin associated with CIK cells against ovarian carcinoma cells]., PMID:23660215
[Apoptosis of human umbilical vein endothelial cells induced by IgA1 isolated from Henoch-Schönlein purpura patients]., PMID:23527930
For research use only. Not for human or drug use.
