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Anti-Human CD166/ALCAM Antibody (SAA0066)

Catalog #:   FHG64010 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1, kappa
Applications: FCM
Accession: Q13740
Overview

Catalog No.

FHG64010

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

Unconjugated

Target

Activated leukocyte cell adhesion molecule, MEMD, CD166 antigen, ALCAM, CD166

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q13740

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0066

Data Image
References

Ex vivo expansion of human disc chondrocytes from surgically removed disc tissue: Post-operative tissue stability., PMID:40501087

The cytotoxic effect of quercetin-induced apoptosis on lung metastatic cells from giant cell tumor of bone., PMID:40418557

Itolizumab regulates activating and inhibitory signals on effector cells, improving their cytotoxicity against CD318+ tumor cell lines., PMID:40391211

Activation of cytotoxic lymphocytes through CD6 enhances killing of cancer cells., PMID:38280067

CD6 and Its Interacting Partners: Newcomers to the Block of Cancer Immunotherapies., PMID:38139340

Activation of Cytotoxic Lymphocytes Through CD6 Enhances Killing of Cancer Cells., PMID:37886483

Targeting Stem Cells and Dysplastic Features With Dual MEK/ERK and STAT3 Suppression in Gastric Carcinogenesis., PMID:37802423

Comprehensive cell surface protein profiling of human mesenchymal stromal cells from peritoneal dialysis effluent and comparison with those from human bone marrow and adipose tissue., PMID:37603218

The influence of antibody CD166 on the treatment of tumor and the immunological mechanism in mice bearing oral squamous cell carcinoma., PMID:37180656

Mesenchymal stromal cell-associated migrasomes: a new source of chemoattractant for cells of hematopoietic origin., PMID:36788616

Keratinocyte-induced costimulation of human T cells through CD6 - but not CD2 - activates mTOR and prevents oxidative stress., PMID:36353616

Proteomic Analysis of HCC-1954 and MCF-7 Cell Lines Highlights Crosstalk between αv and β1 Integrins, E-Cadherin and HER-2., PMID:36077593

Preventive cancer stem cell-based vaccination modulates tumor development in syngeneic colon adenocarcinoma murine model., PMID:36040667

Proteomics Study of Mesenchymal Stem Cell-Like Cells Obtained from Tumor Microenvironment of Patients with Malignant and Benign Salivary Gland Tumors., PMID:35674025

Gene Variation at Immunomodulatory and Cell Adhesion Molecules Loci Impacts Primary Sjögren's Syndrome., PMID:35372412

Praluzatamab Ravtansine, a CD166-Targeting Antibody-Drug Conjugate, in Patients with Advanced Solid Tumors: An Open-Label Phase I/II Trial., PMID:35165101

Adipose mesenchymal stem cells and gingival mesenchymal stem cells have a comparable effect in endothelium repair., PMID:34676008

Calcium channel α2δ1 subunit is a functional marker and therapeutic target for tumor-initiating cells in non-small cell lung cancer., PMID:33707423

Simultaneous Fluorescent Identification of Odontoblasts and Ameloblasts., PMID:33289448

A novel molecular magnetic resonance imaging agent targeting activated leukocyte cell adhesion molecule as demonstrated in mouse brain metastasis models., PMID:33153376

SOSTDC1 promotes invasion and liver metastasis in colorectal cancer via interaction with ALCAM/CD166., PMID:32801337

Stem Cell Marker Expression in Early Stage Colorectal Cancer is Associated with Recurrent Intestinal Neoplasia., PMID:32647988

The tumor targeting performance of anti-CD166 Probody drug conjugate CX-2009 and its parental derivatives as monitored by 89Zr-immuno-PET in xenograft bearing mice., PMID:32483421

Plasmacytoma in patients with multiple myeloma: morphology and immunohistochemistry., PMID:32321465

Attenuation of Murine Collagen-Induced Arthritis by Targeting CD6., PMID:32307907

In silico Analysis, Molecular Docking, Molecular Dynamic, Cloning, Expression and Purification of Chimeric Protein in Colorectal Cancer Treatment., PMID:32158188

Effect of Rho-associated kinase inhibitor on human corneal endothelial cell apoptosis., PMID:32079844

Radiation-Stimulated Translocation of CD166 and CRYAB to the Endothelial Surface Provides Potential Vascular Targets on Irradiated Brain Arteriovenous Malformations., PMID:31757032

Activated leukocyte cell adhesion molecule regulates B lymphocyte migration across central nervous system barriers., PMID:31723036

Enhanced Immunomodulation in Inflammatory Environments Favors Human Cardiac Mesenchymal Stromal-Like Cells for Allogeneic Cell Therapies., PMID:31396228

Axonal Growth of Midbrain Dopamine Neurons is Modulated by the Cell Adhesion Molecule ALCAM Through Trans-Heterophilic Interactions with L1cam, Chl1, and Semaphorins., PMID:31300520

Quantitative Systems Pharmacology Model of a Masked, Tumor-Activated Antibody., PMID:31250966

Domain-specific CD6 monoclonal antibodies identify CD6 isoforms generated by alternative-splicing., PMID:31162836

Back signaling of HLA class I molecules and T/NK cell receptor ligands in epithelial cells reflects the rejection-specific microenvironment in renal allograft biopsies., PMID:31062482

ALCAM Mediates DC Migration Through Afferent Lymphatics and Promotes Allospecific Immune Reactions., PMID:31031759

Anti-CD166/4-1BB chimeric antigen receptor T cell therapy for the treatment of osteosarcoma., PMID:30995926

Isolation and Identification of Murine Bone Marrow-Derived Macrophages and Osteomacs from Neonatal and Adult Mice., PMID:30539348

A sequence conserved between CD5 and CD6 binds an FERM domain and exerts a restraint on T-cell activation., PMID:30460991

Mapping of equine mesenchymal stromal cell surface proteomes for identification of specific markers using proteomics and gene expression analysis: an in vitro cross-sectional study., PMID:30359315

Prophylactic exposure of human corneal endothelial cells to Rho-associated kinase inhibitor reduced apoptosis rate after phacoemulsification: Ex vivo study., PMID:30172567

Stemness and Regenerative Potential of Corneal Stromal Stem Cells and Their Secretome After Long-Term Storage: Implications for Ocular Regeneration., PMID:30046814

CD6 monoclonal antibodies differ in epitope, kinetics and mechanism of action., PMID:29772075

Clinical and experimental evidence for targeting CD6 in immune-based disorders., PMID:29526637

Isolation and characterization of buffalo (bubalus bubalis) amniotic mesenchymal stem cells derived from amnion from the first trimester pregnancy., PMID:29515060

Activated leucocyte cell adhesion molecule (ALCAM/CD166) regulates T cell responses in a murine model of food allergy., PMID:29363753

ILT3.Fc-CD166 Interaction Induces Inactivation of p70 S6 Kinase and Inhibits Tumor Cell Growth., PMID:29263213

A novel bispecific c-MET/CTLA-4 antibody targetting lung cancer stem cell-like cells with therapeutic potential in human non-small-cell lung cancer., PMID:29187584

Tbx18-positive cells differentiated from murine ES cells serve as proepicardial progenitors to give rise to vascular smooth muscle cells and fibroblasts., PMID:28794400

Different RNA and protein expression of surface markers in rabbit amniotic fluid-derived mesenchymal stem cells., PMID:28653478

Intestinal Epithelial Stem Cells: Distinct Behavior After Surgical Injury and Teduglutide Administration., PMID:28362133

Datasheet
$ 225
Product specifications
50 μg 225 100 μg 372

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human CD166/ALCAM Antibody (SAA0066) [FHG64010]
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