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Anti-Human CD161/KLRB1/NK1.1 Antibody (KM12.4.7)

Catalog #:   FHG33810 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1, kappa
Applications: FCM
Accession: Q12918
Overview

Catalog No.

FHG33810

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

Unconjugated

Target

CLEC5B, KLRB1, CD161, HNKR-P1a, C-type lectin domain family 5 member B, NKRP1A, Natural killer cell surface protein P1A, Killer cell lectin-like receptor subfamily B member 1, NKR-P1A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q12918

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

KM12.4.7

Data Image
  • Bioactivity
    Detects Human CD161/KLRB1 in indirect ELISAs.
  • Western Blot
    Various lysates were subjected to SDS PAGE followed by western blot with CD161 antibody (FHG33810) at 1 µg/ml.

    Lane 1: CD161 transfected HEK293 cell lysate
    Lane 2: Non-transfected HEK293 cell lysate

    Second Ab: Goat Anti-Mouse IgG H&L Polyclonal antibody, HRP (PMB96431) at 0.1 μg/mL.

    Predict MW: 46 kDa
    Observed MW: 46 kDa
References

[Protective аction of ginseng root extract on myofibril apoptosis and immune response in rats after exhausting physical exercise. Part II. Effect of ginseng root extract on immunity and regulation of energy metabolism]., PMID:40418135

Anti-SSA/SSB antibody double-negative Sjögren's disease patients: a comprehensive clinical study and immune profile., PMID:39969675

A High-Efficiency Electrochemical Biosensor for the Detection of Mucosal-Associated Invariant T Cells., PMID:39729425

Metabolic Stress Expands Polyfunctional, Proinflammatory Th17 Cells in Patients With Psoriatic Arthritis for Whom There is Interleukin-23-Independent Interleukin-17 Production., PMID:39711043

Targeting LLT1 as a potential immunotherapy option for cancer patients non-responsive to existing checkpoint therapies in multiple solid tumors., PMID:39511540

Immunological insights: assessing immune parameters in medical professionals exposed to SARS-CoV-2., PMID:39187767

A unique human cord blood CD8+CD45RA+CD27+CD161+ T-cell subset identified by flow cytometric data analysis using Seurat., PMID:38798051

Comparative single-cell multiplex immunophenotyping of therapy-naive patients with rheumatoid arthritis, systemic sclerosis, and systemic lupus erythematosus shed light on disease-specific composition of the peripheral immune system., PMID:38726007

Distinct cellular immune responses in children en route to type 1 diabetes with different first-appearing autoantibodies., PMID:38714671

The proportion of CD161 on CD56+ NK cells in peripheral circulation associates with clinical features and disease activity of primary Sjögren's syndrome., PMID:38577997

Combined IL6 and CCR2 blockade potentiates antitumor activity of NK cells in HPV-negative head and neck cancer., PMID:38468260

Study of pathogenic T-helper cell subsets in Asian Indian patients with Takayasu arteritis., PMID:38326692

Targeting of the CD161 inhibitory receptor enhances T-cell-mediated immunity against hematological malignancies., PMID:38153903

mTOR-dependent loss of PON1 secretion and antiphospholipid autoantibody production underlie autoimmunity-mediated cirrhosis in transaldolase deficiency., PMID:37742509

Natalizumab Treatment of Relapsing Remitting Multiple Sclerosis Has No Long-Term Effects on the Proportion of Circulating Regulatory T Cells., PMID:37715885

Vitro UPLC analysis and mass method identification, and in vivo or cellular immune anti-inflammatory function of Sanhuang Xiexin Decoction (SHXD)., PMID:37544343

Hydroxychloroquine reduces T cells activation recall antigen responses., PMID:37531383

Distinct CRTH2+CD161+ (peTh2) memory CD4+ T-cell cytokine profiles in food allergy and eosinophilic gastrointestinal disorders., PMID:37487654

Human in vitro-induced IL-17A+ CD8+ T-cells exert pro-inflammatory effects on synovial fibroblasts., PMID:37367825

Circulating Regulatory T Cell Subsets in Patients with Sarcoidosis., PMID:37189479

Mucosal-associated invariant T cells in patients with axial spondyloarthritis., PMID:36969157

[Bioactive compounds anthocyanins as a factor in the nutritional recovery of the body's adaptive potential after intense physical activity in the experiment: assessment of immunological and hematological indicators of adaptation]., PMID:36883535

KIR/KIR-ligand genotypes and clinical outcomes following chemoimmunotherapy in patients with relapsed or refractory neuroblastoma: a report from the Children's Oncology Group., PMID:36822669

Tissue-Resident Memory T Cells in Pancreatic Ductal Adenocarcinoma Coexpress PD-1 and TIGIT and Functional Inhibition Is Reversible by Dual Antibody Blockade., PMID:36689623

OMIP-088: Twenty-target imaging mass cytometry panel for major cell populations in mouse formalin fixed paraffin embedded liver., PMID:36602064

BCL11B depletion induces the development of highly cytotoxic innate T cells out of IL-15 stimulated peripheral blood αβ CD8+ T cells., PMID:36507091

Regulatory T cells in psoriatic arthritis: an IL-17A-producing, Foxp3intCD161 + RORγt + ICOS + phenotype, that associates with the presence of ADAMTSL5 autoantibodies., PMID:36450783

From IL-17 to IFN-γ in inflammatory skin disorders: Is transdifferentiation a potential treatment target?, PMID:35967358

Identification of a distinct NK-like hepatic T-cell population activated by NKG2C in a TCR-independent manner., PMID:35644434

Clinicopathological Manifestations and Immune Phenotypes in Adult-Onset Immunodeficiency with Anti-interferon-γ Autoantibodies., PMID:35089479

CD161 expression and regulation defines rapidly responding effector CD4+ T cells associated with improved survival in HPV16-associated tumors., PMID:35039463

A case of bronchial asthma as an immune-related adverse event of pembrolizumab treatment for bladder cancer: A case report., PMID:35029177

Characterization of T cell responses to co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in healthy adults in Gabon., PMID:34597297

Inhibitory Receptors and Immune Checkpoints Regulating Natural Killer Cell Responses to Cancer., PMID:34503073

MAIT Cells Balance the Requirements for Immune Tolerance and Anti-Microbial Defense During Pregnancy., PMID:34497611

A Pan-Cancer Analysis of CD161, a Potential New Immune Checkpoint., PMID:34305920

Acute FPIES reactions are associated with an IL-17 inflammatory signature., PMID:33891982

Systems analysis and controlled malaria infection in Europeans and Africans elucidate naturally acquired immunity., PMID:33888898

[Expression of plasma Dickkopf-1 in patients with rheumatoid arthritis and its correlation with peripheral blood T cell subsets]., PMID:33879894

Identifying CNS-colonizing T cells as potential therapeutic targets to prevent progression of multiple sclerosis., PMID:33748804

The number and activity of CD3+TCR Vα7.2+CD161+ cells are increased in children with acute rheumatic fever., PMID:33631279

Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis., PMID:33592174

Persistence of mature dendritic cells, TH2A, and Tc2 cells characterize clinically resolved atopic dermatitis under IL-4Rα blockade., PMID:33483337

Aging and CMV discordance are associated with increased immune diversity between monozygotic twins., PMID:33461563

C-type lectin-like CD161 is not a co-signalling receptor in gluten-reactive CD4 + T cells., PMID:33368526

CD147 Expressed on Memory CD4+ T Cells Limits Th17 Responses in Patients With Rheumatoid Arthritis., PMID:33193313

Investigation of mucosal-associated invariant T (MAIT) cells expressing immune checkpoint receptors (TIGIT and CD226) in early-onset preeclampsia., PMID:32682212

Roles of NK Cell Receptors 2B4 (CD244), CS1 (CD319), and LLT1 (CLEC2D) in Cancer., PMID:32630303

Escherichiacoli-Specific CD4+ T Cells Have Public T-Cell Receptors and Low Interleukin 10 Production in Crohn's Disease., PMID:32361018

Changes of frequency and expression level of CD161 in CD8+ T cells and natural killer T cells in peripheral blood of patients with systemic lupus erythematosus., PMID:32343447

Datasheet
$ 165
Product specifications
50 μg 165 100 μg 272

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Anti-Human CD161/KLRB1/NK1.1 Antibody (KM12.4.7) [FHG33810]
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