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Anti-Human IL17C Antibody (mab#1)

Catalog #:   RHJ70901 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1-kappa
Applications: ELISA, Neutralization
Expression system: Mammalian Cells
Overview

Catalog No.

RHJ70901

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Mouse

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

Cytokine CX2, IL17C, IL-17C, Interleukin-17C

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9P0M4

Applications

ELISA, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

mab#1

Data Image
References

Inflammatory and anti-inflammatory cytokines bidirectionally modulate amygdala circuits regulating anxiety., PMID:40199321

Interleukin-17: A pleiotropic cytokine implicated in inflammatory, infectious, and malignant disorders., PMID:39875232

Successful Treatment of Pediatric Generalized Pustular Psoriasis (GPP) with Spesolimab: 5 Case Reports and Evaluations of Circulating IL-36 Levels., PMID:39525315

Evaluation of inflammatory biomarkers and their association with anti-SARS-CoV-2 antibody titers in healthcare workers vaccinated with BNT162B2., PMID:39247198

Serum protein biomarker profile distinguishes acetylcholine receptor antibody seropositive myasthenia gravis patients from healthy controls., PMID:39165841

Fragile Guts Make Fragile Brains: Intestinal Epithelial Nrf2 Deficiency Exacerbates Neurotoxicity Induced by Polystyrene Nanoplastics., PMID:39158845

Multiarray screening identifies plasma proteins associated with Th17 cell differentiation and viral defense in coincident asthma and obesity., PMID:38967090

IL-17C neutralization protects the kidney against acute injury and chronic injury., PMID:37263138

Plasma protein changes reflect colorectal cancer development and associated inflammation., PMID:37228491

Phase 1 and 2 Randomized Clinical Studies Determine Lack of Efficacy for Anti-IL-17C Antibody MOR106 in Moderate-Severe Atopic Dermatitis., PMID:36498818

Cathelicidin Antimicrobial Peptide LL37 Induces Toll-Like Receptor 8 and Amplifies IL-36γ and IL-17C in Human Keratinocytes., PMID:36496195

Asymptomatic SARS-CoV-2 Infection Is Associated With Higher Levels of Serum IL-17C, Matrix Metalloproteinase 10 and Fibroblast Growth Factors Than Mild Symptomatic COVID-19., PMID:35479098

Bimekizumab for the treatment of moderate-to-severe plaque psoriasis: efficacy, safety, pharmacokinetics, pharmacodynamics and transcriptomics from a phase IIa, randomized, double-blind multicentre study., PMID:34687214

Epicutaneous challenge with protease allergen requires its protease activity to recall TH2 and TH17/TH22 responses in mice pre-sensitized via distant skin., PMID:34487475

Pityriasis Rubra Pilaris Response to IL-17A Inhibition Is Associated with IL-17C and CCL20 Protein Levels., PMID:34246621

Acute FPIES reactions are associated with an IL-17 inflammatory signature., PMID:33891982

Much More Than IL-17A: Cytokines of the IL-17 Family Between Microbiota and Cancer., PMID:33244315

A phase 4, randomized, head-to-head trial comparing the efficacy of subcutaneous injections of brodalumab to oral administrations of fumaric acid esters in adults with moderate-to-severe plaque psoriasis (CHANGE)., PMID:32939860

Tape-Strip Proteomic Profiling of Atopic Dermatitis on Dupilumab Identifies Minimally Invasive Biomarkers., PMID:32849633

The effect of subcutaneous brodalumab on clinical disease activity in hidradenitis suppurativa: An open-label cohort study., PMID:32416208

IL-17C has a pathogenic role in kidney ischemia/reperfusion injury., PMID:32331702

Brodalumab: A new way to inhibit IL-17 in psoriasis., PMID:32285564

Immune Responses and Protective Efficacy of a Formalin-Killed Francisella Noatunensis Subsp. Orientalis Vaccine Evaluated through Intraperitoneal and Immersion Challenge Methods in Oreochromis Niloticus., PMID:32260212

IL-17C/IL-17RE: Emergence of a Unique Axis in TH17 Biology., PMID:32174926

Human Cytomegalovirus (HCMV) Reactivation in the Mammary Gland Induces a Proinflammatory Cytokine Shift in Breast Milk., PMID:32093317

IL-17C amplifies epithelial inflammation in human psoriasis and atopic eczema., PMID:31793105

Early Quantification of Systemic Inflammatory Proteins Predicts Long-Term Treatment Response to Tofacitinib and Etanercept., PMID:31705874

Serum biomarker analysis in patients with premature ovarian insufficiency., PMID:31629109

New treatments for atopic dermatitis targeting beyond IL-4/IL-13 cytokines., PMID:31622669

Brodalumab for the treatment of moderate-to-severe psoriasis: case series and literature review., PMID:31372022

Spotlight on brodalumab in the treatment of plaque psoriasis: the evidence to date., PMID:31118733

Population pharmacokinetics of brodalumab in patients with moderate to severe plaque psoriasis., PMID:30661290

IL-17 inhibitors for psoriasis., PMID:30215631

TSLP Protects Corneas From Pseudomonas aeruginosa Infection by Regulating Dendritic Cells and IL-23-IL-17 Pathway., PMID:30128494

The IL-17 Family of Cytokines in Psoriasis: IL-17A and Beyond., PMID:30127781

IL-17C: A Unique Epithelial Cytokine with Potential for Targeting across the Spectrum of Atopic Dermatitis and Psoriasis., PMID:29941097

IL-17C/IL-17 Receptor E Signaling in CD4+ T Cells Promotes TH17 Cell-Driven Glomerular Inflammation., PMID:29483158

Neutralization of IL-17C Reduces Skin Inflammation in Mouse Models of Psoriasis and Atopic Dermatitis., PMID:29474945

Design and validation of a disease network of inflammatory processes in the NSG-UC mouse model., PMID:29282132

TLN-58, an Additional hCAP18 Processing Form, Found in the Lesion Vesicle of Palmoplantar Pustulosis in the Skin., PMID:27771329

TNF-α inhibitors reduce the pathological Th1 -Th17 /Th2 imbalance in cutaneous mesenchymal stem cells of psoriasis patients., PMID:27376466

Interleukin-9 and interleukin-17C in chronic rhinosinusitis., PMID:26989880

Characterization of Lamprey IL-17 Family Members and Their Receptors., PMID:26491201

CCL7 contributes to the TNF-alpha-dependent inflammation of lesional psoriatic skin., PMID:25828150

IL-36γ sustains a proinflammatory self-amplifying loop with IL-17C in anti-TNF-induced psoriasiform skin lesions of patients with Crohn's disease., PMID:25299544

Gene expression profiles normalized in psoriatic skin by treatment with brodalumab, a human anti-IL-17 receptor monoclonal antibody., PMID:24646743

Expression pattern of serum cytokines in hepatitis B virus infected patients with persistently normal alanine aminotransferase levels., PMID:23954997

IL-17C and its receptor IL-17RA/IL-17RE identify human oral epithelial cell as an inflammatory cell in recurrent aphthous ulcer., PMID:23834281

Keratinocyte overexpression of IL-17C promotes psoriasiform skin inflammation., PMID:23359500

Preferential inhibition of the mRNA expression of p38 mitogen-activated protein kinase regulated cytokines in psoriatic skin by anti-TNFα therapy., PMID:20846304

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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Anti-Human IL17C Antibody (mab#1) [RHJ70901]
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