Catalog No.
RVV09402
Expression system
Mammalian Cells
Species reactivity
Hepatitis C virus genotype 3a (isolate NZL1) (HCV)
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Hepacivirin, NS3 helicase, NS3P, Viroporin p70, Genome polyprotein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q81258
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
28#
Intracellular Delivery of HCV NS3p gene using vectored particles. PMID: 29577966
Hepatitis C virus-NS3P in relation to p53, p21waf, mdm2, p21-ras and c-erbB2 in hepatocarcinogenesis. PMID: 16246194
Backbone ¹H, ¹³C and ¹⁵N resonance assignments of dengue virus NS2B-NS3p in complex with aprotinin. PMID: 22623057
Conformational change study of dengue virus NS2B-NS3 protease using 19F NMR spectroscopy. PMID: 25918021
Flavonoids from Pterogyne nitens as Zika virus NS2B-NS3 protease inhibitors. PMID: 33636437
The conformation of hepatitis C virus NS3 proteinase with and without NS4A: a structural basis for the activation of the enzyme by its cofactor. PMID: 9741640
Binding of a noncovalent inhibitor exploiting the S' region stabilizes the hepatitis C virus NS3 protease conformation in the absence of cofactor. PMID: 19061898
HCV genotype 1-6 NS3 residue 80 substitutions impact protease inhibitor activity and promote viral escape. PMID: 30395912
Differential efficacy of protease inhibitors against HCV genotypes 2a, 3a, 5a, and 6a NS3/4A protease recombinant viruses. PMID: 21699793
Autocatalytic cleavage within classical swine fever virus NS3 leads to a functional separation of protease and helicase. PMID: 23986594
RNA binding by the NS3 protease of the hepatitis C virus. PMID: 22814430
Generation of a chimeric hepatitis C replicon encoding a genotype-6a NS3 protease and assessment of boceprevir (SCH503034) sensitivity and drug-associated mutations. PMID: 25222708
Semliki Forest Virus replicon particles production in serum-free medium BHK-21 cell cultures and their use to express different proteins. PMID: 31422494
Effect of NS3 and NS5B proteins on classical swine fever virus internal ribosome entry site-mediated translation and its host cellular translation. PMID: 18343841
The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site. PMID: 8861916
Hepatitis C virus nonstructural protein NS4B transforms NIH3T3 cells in cooperation with the Ha-ras oncogene. PMID: 10631105
Hepatitis C virus NS3 serine protease interacts with the serpin C1 inhibitor. PMID: 10570951
Competitive inhibition of the dengue virus NS3 serine protease by synthetic peptides representing polyprotein cleavage sites. PMID: 15823576
Mixed-ligand rhenium-188 complexes with tetradentate/monodentate NS3/P ('4 + 1') coordination: relation of structure with antioxidation stability. PMID: 15898732
Electronic structure of H2CS3 and H2CS4: an experimental and theoretical study. PMID: 16919498
For research use only. Not for human or drug use.
