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Anti-HCV NS1/gp68/gp70/Envelope glycoprotein E2 Antibody (mAb#8) (RVV08631)

Host species:Human
Isotype:IgG1, kappa
Applications:ELISA, Neutralization
Expression system:Mammalian Cells
Overview

Catalog No.

RVV08631

Expression system

Mammalian Cells

Species reactivity

Hepatitis C virus genotype 1a (isolate H77) (HCV) & Recombinant Hepatitis C virus H77C/JFH-1

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

NS1, gp68, gp70, Envelope glycoprotein E2, Genome polyprotein

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P27958, B0FYC5

Applications

ELISA, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

mAb#8

Data Image
  • SDS-PAGE
    SDS PAGE for HCV NS1/gp68/gp70/Envelope glycoprotein E2 Antibody (mAb#8)
References

HCV Proteins Modulate the Host Cell miRNA Expression Contributing to Hepatitis C Pathogenesis and Hepatocellular Carcinoma Development. PMID: 34069740

Expression of MBP-HCV NS1/E2 fusion protein in E. coli and detection of anti-NS1/E2 antibody in type C chronic liver disease. PMID: 1314578

Expression of HCV E2/NS1 protein as a fusion protein with maltose binding protein: detection of anti-E2/NS1 antibody in chronic liver disease. PMID: 7686121

Roles of secretory glycoproteins in particle formation of Flaviviridae viruses. PMID: 31342548

Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins. PMID: 1846505

[Hepatitis C]. PMID: 8345654

Hepatitis C and liver transplantation. PMID: 8527717

Degree and distribution of variability in the 5' untranslated, E1, E2/NS1 and NS5 regions of the hepatitis C virus (HCV). PMID: 9751009

Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins. PMID: 28991176

Antibody response to E2/NS1 hepatitis C virus protein in patients with acute hepatitis C. PMID: 9076628

Viral Interference Between Dengue Virus and Hepatitis C Virus Infections. PMID: 32875000

[Hepatitis C immunology]. PMID: 10614142

Secretion and purification of hepatitis C virus NS1 glycoprotein produced by recombinant baculovirus-infected insect cells. PMID: 7686870

Significance of anti-E2 in the diagnosis of HCV infection in patients on maintenance hemodialysis: anti-E2 is frequently detected among anti-HCV antibody-negative patients. PMID: 8959633

Viral loads and E2/NS1 region sequences of hepatitis C virus in hepatocellular carcinoma and surrounding liver. PMID: 9159034

Host-derived apolipoproteins play comparable roles with viral secretory proteins Erns and NS1 in the infectious particle formation of Flaviviridae. PMID: 28644867

Expression and purification of E2/NS1 protein of hepatitis C virus and detection of anti-E2/NS1 antibodies in chronic liver disease patients. PMID: 12595764

Expression of the amino-terminal half of the NS1 region of the hepatitis C virus genome and detection of an antibody to the expressed protein in patients with liver diseases. PMID: 1379627

Syntheses of immunodominant peptide regions of hepatitis C viral pathogens using PS-BDODMA resin: a single peptide derived from the conserved domain (E2/NS1) was highly effective in detecting anti-HCV antibodies. PMID: 11168897

[Evolution of hepatitis C virus (HCV) viremia and adaptation of HCV in persistent infection in patients with acute hepatitis]. PMID: 7521430

[Significance of polypeptide antigen of HCVE2/NS1 relative conservation region in detection of anti-HCV]. PMID: 12759957

Natural history of hepatitis C. PMID: 7529217

Epidemiological studies on hepatitis C virus infection: detection, prevalence, exposure and prevention. PMID: 7814243

Development and Evaluation of a Universal and Supersensitive NS1-Based Luciferase Immunosorbent Assay to Detect Zika Virus-Specific IgG. PMID: 31552611

Structure, genomic organization, replication and variability of hepatitis C virus. PMID: 8918741

Sequence uniqueness and sequence variability as modulating factors of human anti-HCV humoral immune response. PMID: 18256830

[Fundamental studies of hepatitis C virus: a review]. PMID: 1331574

Genomic typing of hepatitis C viruses from Korean patients: implications of genome variation in the E2/NS1 region. PMID: 8240354

Partial nucleotide sequence analysis of a French hepatitis C virus: implications for HCV genetic variability in the E2/NS1 protein. PMID: 1655961

Expression of structural proteins of hepatitis C virus (HCV) in mammalian cells. PMID: 18726270

Translation-competent 48S complex formation on HCV IRES requires the RNA-binding protein NSAP1. PMID: 21715376

[Genomic changes in the E2/NS1 region of HCV before and after IFN therapy in relation to clinical course]. PMID: 7521410

Use of a novel hepatitis C virus (HCV) major-epitope chimeric polypeptide for diagnosis of HCV infection. PMID: 10203493

Hepatitis C transmission between spouses. PMID: 8985816

[Genomic changes in the E2/NS1 region of HCV before and after IFN therapy]. PMID: 7563902

[Innate immune responses against viral infection and its suppression by viral proteins]. PMID: 23449408

Hypervariable 5'-terminus of hepatitis C virus E2/NS1 encodes antigenically distinct variants. PMID: 7689636

Variability of the E2/NS1 region of Swedish hepatitis C virus strains and its correlation to genotypes. PMID: 7939424

A novel antigen detection immunoassay for field diagnosis of hepatitis C virus infection. PMID: 14677657

Analysis of hepatitis C virus capsid, E1, and E2/NS1 proteins expressed in insect cells. PMID: 8212557

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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For research use only. Not for human or drug use.

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Anti-HCV NS1/gp68/gp70/Envelope glycoprotein E2 Antibody (mAb#8) [RVV08631]
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