Anti-HCV NS1/gp68/gp70/Envelope glycoprotein E2 Antibody (HC84-26) (RVV08609)

Catalog No.

RVV08609

Expression system

Mammalian Cells

Species reactivity

Hepatitis C virus genotype 1a (isolate H77) (HCV)

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

NS1, gp68, gp70, Envelope glycoprotein E2, Genome polyprotein

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P27958-2

Applications

ELISA, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

HC84-26

Breadth of neutralization and synergy of clinically relevant human monoclonal antibodies against HCV genotypes 1a, 1b, 2a, 2b, 2c, and 3a. PMID: 25043937

Hypervariable region 1 shielding of hepatitis C virus is a main contributor to genotypic differences in neutralization sensitivity. PMID: 27351277

Native Folding of a Recombinant gpE1/gpE2 Heterodimer Vaccine Antigen from a Precursor Protein Fused with Fc IgG. PMID: 27795422

Recombinant hepatitis C virus envelope glycoprotein vaccine elicits antibodies targeting multiple epitopes on the envelope glycoproteins associated with broad cross-neutralization. PMID: 25275133

Neutralization resistance of hepatitis C virus can be overcome by recombinant human monoclonal antibodies. PMID: 23729237

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Anti-HCV NS1/gp68/gp70/Envelope glycoprotein E2 Antibody (HC84-26).pdf