Catalog No.
DHB96202
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Mouse
Isotype
IgG2b, kappa
Clonality
Monoclonal
Target
T cell receptor alpha chain constant, TRAC, TCRA
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P01848
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
MEDI-500, T10B9, T10B9.1A-31
Clone ID
T10B9.1A-31
T10B9.1A-31 anti-T-cell monoclonal antibody: preclinical studies and clinical treatment of solid organ allograft rejection, PMID: 2479265
Treatment of acute cellular rejection with T10B9.1A-31 or OKT3 in renal allograft recipients, PMID: 1531095
Complement-mediated T-cell depletion of bone marrow: comparison of T10B9.1A-31 and Muromonab-Orthoclone OKT3, PMID: 11953031
Induction immunotherapy in heart transplantation with T10B9.1A-31: a phase I study, PMID: 9322140
T10B9 monoclonal antibody: a short-acting nonstimulating monoclonal antibody that spares gammadelta T-cells and treats and prevents cellular rejection, PMID: 19920935
Treatment of acute rejection with anti-T-cell antigen receptor complex alpha beta (T10B9.1A-31) or anti-CD3 (OKT3) monoclonal antibody: results of a prospective randomized double-blind trial, PMID: 1899152
Combined in vitro and in vivo T lymphocyte depletion for the control of graft-versus-host disease following haploidentical marrow transplant, PMID: 8607177
Increased frequency of TCR gamma delta + T cells in disease-free survivors following T cell-depleted, partially mismatched, related donor bone marrow transplantation for leukemia, PMID: 8938522
Analysis of risk factors for the development of GVHD after T cell-depleted allogeneic BMT: effect of HLA disparity, ABO incompatibility, and method of T-cell depletion, PMID: 11760150
Allogeneic bone marrow transplantation with T cell-depleted partially matched related donors for advanced acute lymphoblastic leukemia in children and adults: a comparative matched cohort study, PMID: 8807094
For research use only. Not for human or drug use.
