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Research Grade Risankizumab (DHJ63101)

Host species:Humanized
Isotype:IgG1-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHJ63101

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

SGRF, IL-23-A, IL-23 subunit alpha, Interleukin-23 subunit p19, IL23A, Interleukin-23 subunit alpha, IL-23p19

Concentration

5.1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9NPF7

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

BI 655066, risankizumab-rzaa, CAS: 1612838-76-2

Clone ID

Risankizumab

Data Image
  • SDS-PAGE
    SDS PAGE for Risankizumab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Risankizumab for the treatment of psoriasis, PMID: 31460804

Risankizumab: First Global Approval, PMID: 31098898

Risankizumab: A Review in Moderate to Severe Plaque Psoriasis, PMID: 32632826

Risankizumab: an anti-IL-23 antibody for the treatment of psoriasis, PMID: 30518998

Risankizumab versus Ustekinumab for Moderate-to-Severe Plaque Psoriasis, PMID: 28423301

Risankizumab for psoriasis, PMID: 32346218

Efficacy and safety of risankizumab vs. secukinumab in patients with moderate-to-severe plaque psoriasis (IMMerge): results from a phase III, randomized, open-label, efficacy-assessor-blinded clinical trial, PMID: 32594522

Risankizumab in the treatment of psoriasis - literature review, PMID: 31462831

Update on risankizumab for the treatment of moderate to severe psoriasis, PMID: 32933320

Efficacy and safety of risankizumab in moderate-to-severe plaque psoriasis (UltIMMa-1 and UltIMMa-2): results from two double-blind, randomised, placebo-controlled and ustekinumab-controlled phase 3 trials, PMID: 30097359

Risankizumab in patients with moderate to severe Crohn's disease: an open-label extension study, PMID: 30056030

Risankizumab compared with adalimumab in patients with moderate-to-severe plaque psoriasis (IMMvent): a randomised, double-blind, active-comparator-controlled phase 3 trial, PMID: 31280967

Pathophysiology, Clinical Presentation, and Treatment of Psoriasis: A Review, PMID: 32427307

Short-Term Efficacy and Safety of IL-17, IL-12/23, and IL-23 Inhibitors Brodalumab, Secukinumab, Ixekizumab, Ustekinumab, Guselkumab, Tildrakizumab, and Risankizumab for the Treatment of Moderate to Severe Plaque Psoriasis: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials, PMID: 31583255

Psoriatic skin molecular and histopathologic profiles after treatment with risankizumab versus ustekinumab, PMID: 30578873

Induction therapy with the selective interleukin-23 inhibitor risankizumab in patients with moderate-to-severe Crohn's disease: a randomised, double-blind, placebo-controlled phase 2 study, PMID: 28411872

Efficacy and Safety of Continuous Risankizumab Therapy vs Treatment Withdrawal in Patients With Moderate to Severe Plaque Psoriasis: A Phase 3 Randomized Clinical Trial, PMID: 32267471

Clinical Pharmacokinetics and Pharmacodynamics of Risankizumab in Psoriasis Patients, PMID: 31758502

A drug safety evaluation of risankizumab for psoriasis, PMID: 32100591

Risankizumab, PMID: 31145575

Risankizumab in moderate-to-severe plaque psoriasis, PMID: 31578912

Effect of Risankizumab on Patient-Reported Outcomes in Moderate to Severe Psoriasis: The UltIMMa-1 and UltIMMa-2 Randomized Clinical Trials, PMID: 33052382

Efficacy of risankizumab in patients with moderate-to-severe plaque psoriasis by baseline demographics, disease characteristics and prior biologic therapy: an integrated analysis of the phase III UltIMMa-1 and UltIMMa-2 studies, PMID: 32320088

Efficacy and safety of risankizumab in Japanese patients with moderate to severe plaque psoriasis: Results from the SustaIMM phase 2/3 trial, PMID: 31237727

Risankizumab, an IL-23p19 Inhibitor for Psoriasis: A Review of the Current Literature, PMID: 32510689

Efficacy and safety of Risankizumab in moderate to severe psoriasis: A systematic review and meta-analysis, PMID: 33140468

Clinical Evaluation of Risankizumab-rzaa in the Treatment of Plaque Psoriasis, PMID: 32158251

Risankizumab for the treatment of moderate to severe psoriasis, PMID: 30462554

Risankizumab.rzaa: an interleukin monoclonal antibody antagonist binding to the p19 subunit of human IL-23 cytokine, PMID: 31720558

Efficacy and safety of risankizumab in psoriasis patients who failed anti-IL-17, anti-12/23 and/or anti IL-23: Preliminary data of a real-life 16-week retrospective study, PMID: 32761740

Antibodies to watch in 2020, PMID: 31847708

Risankizumab vs. ustekinumab for plaque psoriasis: a critical appraisal, PMID: 30632140

Spotlight on risankizumab and its potential in the treatment of plaque psoriasis: evidence to date, PMID: 30519540

Risankizumab for the Treatment of Moderate to Severe Plaque Psoriasis, PMID: 31672037

Efficacy of in-class interleukin-23 inhibitor switching: risankizumab following guselkumab failure in moderate-to-severe psoriasis treatment, PMID: 32998185

Risankizumab for psoriasis, PMID: 30097360

Risankizumab (Skyrizi) for psoriasis, PMID: 31170118

Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with biologics, PMID: 30772098

Pharmacoeconomic Review Report: Risankizumab (Skyrizi): (AbbVie) [Internet], PMID: 31876996

Risankizumab: How to choose the right dose in clinical practice?, PMID: 33021745

Risankizumab, PMID: 34251778

Romosozumab-aqqg, upadacitinib, and risankizumab-rzaa, PMID: 31735342

Risankizumab-Aggravated Crusted Scabies in a Patient with Down Syndrome, PMID: 32378153

Risankizumab as a promising therapeutic approach in obese patients, PMID: 32196833

New Treatment Addressing the Pathogenesis of Psoriasis, PMID: 33050592

Acrodermatitis continua Hallopeau successfully treated by risankizumab, PMID: 33368238

Risankizumab vs. adalimumab for moderate-to-severe plaque psoriasis: a critical appraisal, PMID: 31899817

Clinical Review Report: Risankizumab (Skyrizi): (AbbVie) [Internet], PMID: 31393686

Comparison of Biologics and Oral Treatments for Plaque Psoriasis: A Meta-analysis, PMID: 32022825

Risankizumab: a game changer in Crohn's disease?, PMID: 30056029

Datasheet

Document Download

Research Grade Risankizumab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

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Research Grade Risankizumab [DHJ63101]
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