Catalog No.
DXX02301
Expression system
Mammalian Cells
Species reactivity
Candida albicans
Host species
Human
Isotype
scFv-heavy-kappa
Clonality
Monoclonal
Target
HSP90
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P46598
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
HSP90mab, Mycograb, CAS: 762260-74-2
Clone ID
Efungumab
Efungumab: a novel agent in the treatment of invasive candidiasis, PMID: 19773528
Efungumab and caspofungin: pre-clinical data supporting synergy, PMID: 18299636
Successful treatment of life-threatening Candida peritonitis in a child with abdominal non-Hodgkin lymphoma using Efungumab and amphotericin B colloid dispersion, PMID: 20098335
Invasive candidiasis: update on current pharmacotherapy options and future perspectives, PMID: 23724798
Heat shock protein inhibitors for the treatment of fungal infections, PMID: 21192778
Gateways to clinical trials. July-August 2008, PMID: 18850047
Potential of anti-Candida antibodies in immunoprophylaxis, PMID: 20635926
Human monoclonal antibody-based therapy in the treatment of invasive candidiasis, PMID: 23878583
[Advances in the diagnosis and treatment of yeast infections: role of the new antifungal agents], PMID: 19100166
Treatment of a critically ill child with disseminated Candida glabrata with a recombinant human antibody specific for fungal heat shock protein 90 and liposomal amphotericin B, caspofungin, and voriconazole, PMID: 18843247
Nonspecific effect of Mycograb on amphotericin B MIC, PMID: 22508314
Human recombinant antibody against Candida, PMID: 17006302
Mycograb for the treatment of invasive candidiasis, PMID: 16983626
Dose range evaluation of Mycograb C28Y variant, a human recombinant antibody fragment to heat shock protein 90, in combination with amphotericin B-desoxycholate for treatment of murine systemic candidiasis, PMID: 21502626
A randomized, blinded, multicenter trial of lipid-associated amphotericin B alone versus in combination with an antibody-based inhibitor of heat shock protein 90 in patients with invasive candidiasis, PMID: 16619152
For research use only. Not for human or drug use.
