Catalog No.
DHF46301
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG4-lambda
Clonality
Monoclonal
Target
Glioblastoma-derived T-cell suppressor factor, TGF-beta-2, LAP, G-TSF, TGFB2, Cetermin, Transforming growth factor beta-2 proprotein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P61812
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
CAT-152, Trabio, CAS: 285985-06-0
Clone ID
Lerdelimumab
A phase III study of subconjunctival human anti-transforming growth factor beta(2) monoclonal antibody (CAT-152) to prevent scarring after first-time trabeculectomy, PMID: 17908591
CAT-152 Trabeculectomy Study, PMID: 17908596
Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery, PMID: 12882787
Factors affecting the outcome of trabeculectomy: an analysis based on combined data from two phase III studies of an antibody to transforming growth factor beta2, CAT-152, PMID: 17719641
Gateways to clinical trials, PMID: 12808477
Large- and small-molecule inhibitors of transforming growth factor-beta signaling, PMID: 16784021
Lerdelimumab, PMID: 12001808
Short-term exposure to transforming growth factor beta induces long-term fibrotic responses, PMID: 16934251
Strategies for TGF-beta modulation: a review of recent patents, PMID: 19939191
Technology evaluation: lerdelimumab, Cambridge Antibody Technology, PMID: 12772512
TGF-beta(2) antibody in trabeculectomy, PMID: 19118706
TGF-beta2-induced matrix modification and cell transdifferentiation in the human lens capsular bag, PMID: 12091431
Trabeculectomy outcomes, PMID: 18519074
For research use only. Not for human or drug use.
