Catalog No.
DXX02202
Expression system
Mammalian Cells
Species reactivity
Gram negative bacteria
Host species
Human
Isotype
IgM
Clonality
Monoclonal
Target
Endotoxin (Lipid A)
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
E5, XMMEN-0E5, CAS: 141410-98-2
Clone ID
Edobacomab
[Phase I study of edobacomab (E5) in patients with gram-negative sepsis], PMID: 8138680
Antiendotoxin monoclonal antibodies. What future now?, PMID: 7848542
Monoclonal antibodies to endotoxin in the management of sepsis, PMID: 8317126
[Phase II study of edobacomab (E5) in the treatment of gram-negative sepsis], PMID: 8138682
Gram-negative sepsis, the sepsis syndrome, and the role of antiendotoxin monoclonal antibodies, PMID: 1611812
Identification of important residues in metal-chelate recognition by monoclonal antibodies, PMID: 14640685
Another negative clinical trial of a new agent for the treatment of sepsis: rethinking the process of developing adjuvant treatments for serious infections, PMID: 7774236
Antiendotoxin therapy in sepsis, PMID: 8398040
E5 murine monoclonal antiendotoxin antibody in gram-negative sepsis: a randomized controlled trial. E5 Study Investigators, PMID: 10755499
Who should receive antiendotoxin monoclonal antibody therapy?, PMID: 1611815
Monoclonal antibodies for gram-negative sepsis, PMID: 1943976
Localisation of clusterin in normal human sperm by immunogold electron microscopy, PMID: 11186422
Criteria for use of antiendotoxin monoclonal antibodies (HA-1A and E5) in adult and pediatric inpatients, PMID: 1611816
Preincubation of endotoxin with monoclonal anti-lipid A (E5), but not in vivo treatment, inhibits circulatory dysfunction, PMID: 7496898
For research use only. Not for human or drug use.
