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Recombinant Human HIF1A Protein, N-His

Catalog #:   YHH34301 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: Q16665
Protein length: Arg575-Asn826
Overview

Catalog No.

YHH34301

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Arg575-Asn826

Predicted molecular weight

29.79 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

Q16665

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

HIF1A, MOP1, bHLHe78, Basic-helix-loop-helix-PAS protein MOP1, HIF-1-alpha, BHLHE78, Member of PAS protein 1, Hypoxia-inducible factor 1-alpha, ARNT-interacting protein, PAS domain-containing protein 8, HIF1-alpha, PASD8, Class E basic helix-loop-helix protein 78

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human HIF1A protein
References

Pharmacological HIF-PH Inhibition Suppresses Myoblast Differentiation Through Continued HIF-1α Stabilization., PMID:40508217

ADAM32 Oncogene in Hepatoblastoma Is Regulated by IGF2BP2., PMID:40507253

Injectable Methylcellulose/Hyaluronic Acid/Collagen Hydrogel Loaded With Adipose-Derived Stem Cells Alleviates Skin Photoaging via Inhibition of HIF-1α: An in Vitro and in Vivo Study., PMID:40504120

Dynamic VOC fingerprinting and mechanistic exploration of medicinal edible fungus Inonotus hispidus: A combination of HS-GC-IMS/MS multivariate analysis and network-based pharmacology., PMID:40499502

Purinergic Receptor P2Y2 Activity Prevents DNA Damage in CCl4-Induced Hepatic Fibrosis., PMID:40495470

MicroRNA-6084 orchestrates angiogenesis and liver metastasis in colorectal cancer via extracellular vesicles., PMID:40493409

HIF-1α Promotes Inflammatory Responses in Aspergillus Fumigatus Keratitis by Activating Pyroptosis Through Caspase-8/GSDMD Pathway., PMID:40492985

Inhibitors of p53 Apoptosis-Stimulating Protein Mitigate Acute Kidney Injury by Modulating the HIF-1α/SLC7A11 Pathway to Suppress Ferroptosis., PMID:40492946

Identification of autophagy-related genes in intestinal ischemia-reperfusion injury and their role in immune infiltration., PMID:40491449

Sex- and subregion-specific vulnerability of the hippocampus and amygdala to intermittent hypoxia in relation to learning/memory function and anxiety tendencies of infant rats., PMID:40490588

Unveiling pharmacological targets of Rihimaside C for radiation-induced lung injury: An in silico and experimental integrated approach., PMID:40486275

Natural Flavonoids as Anticancer Agents: Targeting the HIF-1α Signaling Pathway., PMID:40484654

Comparative analysis of respiratory metabolism, blood physiology, antioxidant capacity, and hypoxia-related gene expression in Snowy White chickens raised at high and low altitudes., PMID:40483906

Senescence caused by telomerase inactivation in myeloid, mesenchymal, and endothelial cells has distinct effects on cancer progression., PMID:40482194

Unraveling anti-atherosclerosis mechanism of anthocyanins from Xinjiang wild cherry plum (Prunus divaricata Ledeb) via network pharmacology and molecular docking., PMID:40478326

Oxygen-Generating Biomimetic Nano-Herb System for Synergistic Therapy & Pain Relief in Triple-Negative Breast Cancer via HIF-1α/VEGF Pathway., PMID:40470112

Computational and Molecular Profiling of the Anticancer Properties of Thuja occidentalis L. From Southern Punjab., PMID:40468803

Hypoxia-inducible factor-1 alpha and nuclear factor erythroid 2-related factor 2 as biomarkers of renal scarring in children with congenital anomalies of the kidney and urinary tract: a prospective case-control study., PMID:40468229

Chemoproteomics reveals Ailanthone directly binds to PKM2 to inhibit the progression of Hepatocellular carcinoma., PMID:40466508

Srebf and Runx3 regulate hepatic HMG-CoA reductase and intracellular cholesterol under hypoxia., PMID:40464811

A novel oncogene, leucine-rich repeat protein 1, mediates hypoxia-induced hepatocellular carcinoma progression., PMID:40459634

Short-Term DMOG treatment rejuvenates senescent mesenchymal stem cells by enhancing mitochondrial function and mitophagy through the HIF-1α/BNIP3 pathway., PMID:40457488

Ubiquitin C-terminal hydrolase L1 promoted pro-angiogenic capacity of periodontal ligament stem cells via HIF-1α/YAP signaling in periodontitis., PMID:40457476

The cell-permeable iron chelator M606 inhibits MYCN-driven neuroblastoma via an E2F3-mediated response., PMID:40455982

Enhancement of endometrial receptivity by Bushen Zhuyun Decoction via cryptotanshinone-mediated TRIM28 induction and HIF-1α suppression., PMID:40449692

FTVI promotes osteogenic differentiation of bone marrow mesenchymal stem cells through LncRNA HIF1A-AS2., PMID:40448168

Computational investigation and experimental validation of the molecular mechanism of Solanecio mannii aqueous roots extract against cervical cancer., PMID:40446016

Differences in the Blood Levels of HIF-1α and VNN1 and Expression of HIF1A and NFKB1 in Leukocytes in Cardiological Patients with Risk of Postoperative Complications., PMID:40445541

Reduced iron bioavailability drives acute high‑altitude lung injury through HIF1α activation and mitophagy., PMID:40444479

Analysis of Specific MicroRNAs Expressed after Intake of Cobalt and Xenon Preparations for Anti-Doping Control., PMID:40442471

RNF20 links the DNA damage response and metabolic rewiring in lung cancer through HIF1α., PMID:40436847

Inactivation of the PHD3-FOXO3 axis blunts the type I interferon response in microglia and ameliorates Alzheimer's disease progression., PMID:40435260

Correlation between changes in haemorheology and the HIF-1/EPO pathway in children with Mycoplasma pneumoniae pneumonia., PMID:40434092

Role of Digoxin in Preventing Cigarette Smoke-Induced COPD via HIF-1α Inhibition in a Mouse Model., PMID:40433398

A Study on the Levels of Selected Proangiogenic Proteins in Human Tissues and Plasma in Relation to Brain Glioma., PMID:40429943

Characterization of Extrachromosomal Circular DNA in Primary and Cisplatin-Resistant High-Grade Serous Ovarian Cancer., PMID:40428339

HIF1A Regulates Rhbg Expression to Enhance Ammonia Excretion in Amur Ide (Leuciscus waleckii) Under Extreme Alkaline Conditions., PMID:40427687

CA9-Positive Keloid Fibroblasts: Modulator of Local Inflammation Induced by the Hypoxic and Glycolysis-enhanced Microenvironment., PMID:40425327

ASAP1 protein macromolecule promotes the growth and development of gastric cancer cells and the remodeling of F-actin cytoskeleton: Expression of VEGF and HIF-1 α proteins., PMID:40424906

TAMs-derived SPP1, regulated by HIF-1α/STAT3 signaling pathway, influences colorectal cancer malignant progression by activation of EMT via integrin αvβ3., PMID:40424660

Rotenoids from the Roots of Vicia faba L. (Fabaceae): Structural Characterization, Cytotoxic Effects, and Molecular Docking., PMID:40418826

Mechanistic study of the association between microRNA-126 and hypertension in obstructive sleep apnea-hypopnea syndrome., PMID:40418154

Mechanism Analysis of Zuogui and Yougui Pills on Diabetic Nephropathy Through Transcriptional Regulatory Networks of HIF1A and PPARA., PMID:40417738

[Curcumin inhibits lipid metabolism in non-small cell lung cancer by downregulating the HIF-1α pathway]., PMID:40415436

[Eye acupuncture improves neural function in rats with cerebral ischemia-reperfusion injury by promoting angiogenesis via upregulating METTL3-mediated m6A methylation]., PMID:40415423

Hypoxia-inducible factor-1α promotes tubulointerstitial fibrosis via the upregulation of Muc4., PMID:40415252

Microplastic exposure induces preeclampsia-like symptoms via HIF-1α/TFRC-mediated ferroptosis in placental trophoblast cells., PMID:40414414

Unraveling the metabolic gene expression and energetic patterns of the seasonally acclimatized gilthead seabream., PMID:40411699

Exosomal PD-L1 derived from hypoxia nasopharyngeal carcinoma cell exacerbates CD8+ T cell suppression by promoting PD-L1 upregulation in macrophages., PMID:40411570

Carbonic anhydrase IX downregulation linked to disruption of HIF-1, NFκB and STAT3 pathways as a new mechanism of ibuprofen anti-cancer effect., PMID:40408503

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human HIF1A Protein, N-His [YHH34301]
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