Catalog No.
YHF95801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr2-Ala459
Predicted molecular weight
78.51 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q02790
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PPIase FKBP4, FKBP51, HSP-binding immunophilin, FKBP52, p59, HBI, Rotamase, Peptidyl-prolyl cis-trans isomerase FKBP4, FKBP4, FKBP59, 51 kDa FK506-binding protein, 52 kDa FK506-binding protein, FK506-binding protein 4, FKBP-4, 59 kDa immunophilin, FKBP-52, Immunophilin FKBP52, 52 kDa FKBP
New biomarkers of Kawasaki disease identified by gingival crevicular fluid proteomics., PMID:40421421
Xiao Yao San mitigates corticosterone stimulation-induced hippocampal neuronal damage by inhibiting GR phosphorylation and nuclear translocation via FKBP4 involvement., PMID:40269902
The rs1360780 Variant of FKBP5: Genetic Variation, Epigenetic Regulation, and Behavioral Phenotypes., PMID:40149476
Identification of Candidate Lung Function-Related Plasma Proteins to Pinpoint Drug Targets for Common Pulmonary Diseases: A Comprehensive Multi-Omics Integration Analysis., PMID:40136421
Ectopic protein lysine methacrylation contributes to defects caused by loss of HIBCH or ECHS1., PMID:40056416
Exploring the role of glucocorticoid receptors and co-chaperones in Pemphigus foliaceus stratification., PMID:39988616
Integrated genomic analysis of the stemness index signature of mRNA expression predicts lung adenocarcinoma prognosis and immune landscape., PMID:39959839
SKA2 enhances stress-related glucocorticoid receptor signaling through FKBP4-FKBP5 interactions in neurons., PMID:39705315
Self-Healing COCu-Tac Hydrogel Enhances iNSCs Transplantation for Spinal Cord Injury by Promoting Mitophagy via the FKBP52/AKT Pathway., PMID:39587837
FKBP4 promotes glycolysis and hepatocellular carcinoma progression via p53/HK2 axis., PMID:39505995
The implication of ADRA2A and AVPRIB gene variants in the aetiology of stress-related bipolar disorder., PMID:39278467
A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo., PMID:39119047
Molecular evidence of altered stress responsivity related to neuroinflammation in the schizophrenia midbrain., PMID:39004003
NFAT activation by FKBP52 promotes cancer cell proliferation by suppressing p53., PMID:38803221
Pan-cancer analysis of the prognostic and immunological role of FKBP4., PMID:38601662
Secretome Analyses Identify FKBP4 as a GBA1-Associated Protein in CSF and iPS Cells from Parkinson's Disease Patients with GBA1 Mutations., PMID:38203854
Blood mRNA expression levels of glucocorticoid receptors and FKBP5 are associated with depressive disorder and altered HPA axis., PMID:38199409
Suppression of mir-150-5p attenuates the anti-inflammatory effect of glucocorticoids in mice with ulcerative colitis., PMID:37729776
Human adenovirus DNA polymerase is evolutionarily and functionally associated with human telomerase reverse transcriptase based on in silico molecular characterization that implicate abacavir and zidovudine., PMID:37351013
Concomitant Neuronal Tau Deposition and FKBP52 Decrease Is an Early Feature of Different Human and Experimental Tauopathies., PMID:37248902
Structure and function of the TPR-domain immunophilins FKBP51 and FKBP52 in normal physiology and disease., PMID:37087733
Acute Ozone-Induced Transcriptional Changes in Markers of Oxidative Stress and Glucocorticoid Signaling in the Rat Hippocampus and Hypothalamus Are Sex-Specific., PMID:37047376
Impact of FKBP52 on cell proliferation and hormone-dependent cancers., PMID:37026526
Melatonin-mediated FKBP4 downregulation protects against stress-induced neuronal mitochondria dysfunctions by blocking nuclear translocation of GR., PMID:36810730
Structural and biochemical insights into FKBP51 as a Hsp90 co-chaperone., PMID:36791213
Cortisol/glucocorticoid receptor: a critical mediator of the ovulatory process and luteinization in human periovulatory follicles., PMID:36752644
Penetrating Exploration of Prognostic Correlations of the FKBP Gene Family with Lung Adenocarcinoma., PMID:36675710
Utilizing MALDI-TOF MS and LC-MS/MS to access serum peptidome-based biomarkers in canine oral tumors., PMID:36517562
Identification of Specific Cervical Cancer Subtypes and Prognostic Gene Sets in Tumor and Nontumor Tissues Based on GSVA Analysis., PMID:36284631
NR3C1 and glucocorticoid-regulatory genes mRNA and protein expression in the endometrium and ampulla during the bovine estrous cycle., PMID:36174371
FKBP4 correlates with CD8+ T cells and lymphatic metastases in oral squamous cell carcinoma., PMID:36067001
Apoptosis and glucocorticoid-related genes mRNA expression is modulated by coenzyme Q10 supplementation during in vitro maturation and vitrification of bovine oocytes and cumulus cells., PMID:36063671
FKBP4 regulates 5-fluorouracil sensitivity in colon cancer by controlling mitochondrial respiration., PMID:35981890
E2F Transcription Factor 1 Activates FKBP Prolyl Isomerase 4 to Promote Angiogenesis in Cervical Squamous Cell Carcinoma Via the PI3K/AKT Signaling Pathway., PMID:35849266
LncRNA MAFG-AS1 deregulated in breast cancer affects autophagy and progression of breast cancer by interacting with miR-3612 and FKBP4 invitro., PMID:35653827
Corticosterone Levels and Glucocorticoid Receptor Gene Expression in High Drinking in the Dark Mice and Their Heterogeneous Stock (HS/NPT) Founder Line., PMID:35645743
Effects of RU486 in Treatment of Traumatic Stress-Induced Glucocorticoid Dysregulation and Fear-Related Abnormalities: Early versus Late Intervention., PMID:35628305
FKBP52 and FKBP51 differentially regulate the stability of estrogen receptor in breast cancer., PMID:35394865
Insight Into Pituitary lncRNA and mRNA at Two Estrous Stages in Small Tail Han Sheep With Different FecB Genotypes., PMID:35178025
FKBP52 in Neuronal Signaling and Neurodegenerative Diseases: A Microtubule Story., PMID:35163662
Comprehensive analysis of FKBP4/NR3C1/TMEM173 signaling pathway in triple-negative breast cancer cell and dendritic cell among tumor microenvironment., PMID:35118194
Naringenin Regulates FKBP4/NR3C1/NRF2 Axis in Autophagy and Proliferation of Breast Cancer and Differentiation and Maturation of Dendritic Cell., PMID:35087512
Hypothalamic Regulation of Corticotropin-Releasing Factor under Stress and Stress Resilience., PMID:34830130
KDM5D inhibits the transcriptional activation of FKBP4 by suppressing the expression of E2F1 in colorectal cancer in males., PMID:34688635
Differential Abundance of Brain Mitochondrial Proteins in Yak and Cattle: A Proteomics-Based Study., PMID:34532350
FKBP51 and the molecular chaperoning of metabolism., PMID:34481731
Acute heat stress reduces viability but increases lactate secretion of porcine immature Sertoli cells through transcriptome reprogramming., PMID:34392171
[miR-483-5p aggravates cisplatin-induced premature ovarian insufficiency in rats by targeting FKBP4]., PMID:34238731
FKBP4 integrates FKBP4/Hsp90/IKK with FKBP4/Hsp70/RelA complex to promote lung adenocarcinoma progression via IKK/NF-κB signaling., PMID:34112753
Differential Effects of Fkbp4 and Fkbp5 on Regulation of the Proopiomelanocortin Gene in Murine AtT-20 Corticotroph Cells., PMID:34072036
For research use only. Not for human or drug use.
