Catalog No.
EHE14001
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-His205
Predicted molecular weight
23.09 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
NP_940991.1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Hepatoma-associated antigen, BSG, HAb18G, 5F7, TCSF, OK blood group antigen, Collagenase stimulatory factor, CD147, Leukocyte activation antigen M6, Basigin, Extracellular matrix metalloproteinase inducer, EMMPRIN, Tumor cell-derived collagenase stimulatory factor
Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma. PMID: 32968061
The CD147-HYALURONAN Axis in Cancer. PMID: 31090215
Role of CD147 (EMMPRIN/Basigin) in Tissue Remodeling. PMID: 30768865
Role of melatonin in the treatment of COVID-19; as an adjuvant through cluster differentiation 147 (CD147). PMID: 32920757
[CD147: role and therapeutic targeting of a promising molecule in the treatment of cancers]. PMID: 33052094
CD147 and glioma: a meta-analysis. PMID: 28560663
CD147 in ovarian and other cancers. PMID: 23221648
CD147 Aggravated Inflammatory Bowel Disease by Triggering NF-kappaB-Mediated Pyroptosis. PMID: 32714980
The roles of CyPA and CD147 in cardiac remodelling. PMID: 29772453
Targeted degradation of CD147 proteins in melanoma. PMID: 33197849
Repressing CD147 is a novel therapeutic strategy for malignant melanoma. PMID: 28445958
CD147 Expression Is Associated with Tumor Proliferation in Bladder Cancer via GSDMD. PMID: 32149134
The expression of SARS-CoV-2 receptor ACE2 and CD147, and protease TMPRSS2 in human and mouse brain cells and mouse brain tissues. PMID: 33008593
CD147 promotes collective invasion through cathepsin B in hepatocellular carcinoma. PMID: 32727598
EMMPRIN/CD147 plays a detrimental role in clinical and experimental ischemic stroke. PMID: 32191628
The roles of CD147 in the progression of gliomas. PMID: 26414447
CD147-mediated reprogrammed glycolytic metabolism potentially induces immune escape in the tumor microenvironment (Review). PMID: 30864716
CD147 in cardiovascular disease and thrombosis. PMID: 25280014
CD147 as a Novel Prognostic Biomarker for Hepatocellular Carcinoma: A Meta-Analysis. PMID: 28386553
Clinical Significance of CD147 in Children with Inflammatory Bowel Disease. PMID: 33015178
CD147: a novel modulator of inflammatory and immune disorders. PMID: 24372217
CD147/EMMPRIN overexpression and prognosis in cancer: A systematic review and meta-analysis. PMID: 27608940
Structural insights on druggable hotspots in CD147: A bull's eye view. PMID: 30904494
Cancer-related issues of CD147. PMID: 20551248
CD147 (EMMPRIN/Basigin) in kidney diseases: from an inflammation and immune system viewpoint. PMID: 25248362
CD147 increases mucus secretion induced by cigarette smoke in COPD. PMID: 30727993
Function of CD147 in atherosclerosis and atherothrombosis. PMID: 25604960
Hepatic CD147 knockout modulates liver steatosis and up-regulates autophagy in high-fat-diet-induced NAFLD mice. PMID: 32063360
Importance of N-glycosylation on CD147 for its biological functions. PMID: 24739808
Extracellular Matrix Metalloproteinase Inducer EMMPRIN (CD147) in Cardiovascular Disease. PMID: 29419744
CD147 is a Novel Interaction Partner of Integrin alphaMbeta2 Mediating Leukocyte and Platelet Adhesion. PMID: 32252487
Downregulation of CyclophilinA/CD147 Axis Induces Cell Apoptosis and Inhibits Glioma Aggressiveness. PMID: 32775435
Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics. PMID: 20345978
CD147/basigin promotes progression of malignant melanoma and other cancers. PMID: 20060267
CD147 Expressed on Memory CD4(+) T Cells Limits Th17 Responses in Patients With Rheumatoid Arthritis. PMID: 33193313
Dealing with the family: CD147 interactions with cyclophilins. PMID: 16476049
CD147 Promotes CXCL1 Expression and Modulates Liver Fibrogenesis. PMID: 29642635
CD147 self-regulates matrix metalloproteinase-2 release in gingival fibroblasts after coculturing with U937 monocytic cells. PMID: 31557319
Role of CD147 in regulating the RSK2/Slug/EMT pathway in diabetic foot ulcer healing. PMID: 33053534
CD147 in regulatory T cells. PMID: 23665204
CD147: regulator of hyaluronan signaling in invasiveness and chemoresistance. PMID: 25081536
The phosphorylation of CD147 by Fyn plays a critical role for melanoma cells growth and metastasis. PMID: 32291412
CD147 is critical for cancer stem cell chemoresistance: what does this mean for the clinic? PMID: 23992413
CD147 mediates intrahepatic leukocyte aggregation and determines the extent of liver injury. PMID: 31291257
CD147 as an alternative binding site for the spike protein on the surface of SARS-CoV-2. PMID: 33336782
The role of EMMPRIN/CD147 in regulating angiogenesis in patients with psoriatic arthritis. PMID: 33054815
CD147 as an apoptosis regulator in spermatogenesis: deciphering its association with matrix metalloproteinases' pathway. PMID: 30600459
Tumor-stroma interaction increases CD147 expression in neoplastic B lymphocytes in chronic lymphocytic leukemia. PMID: 32007924
CD147 immunoglobulin superfamily receptor function and role in pathology. PMID: 17945211
Correlation between serum CD147 and carotid intraplaque hemorrhage. PMID: 30440140
For research use only. Not for human or drug use.
