Catalog No.
YHE02301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly457-Val698
Predicted molecular weight
29.28 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P33121
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FACL1, LACS2, Long-chain acyl-CoA synthetase 1, Long-chain acyl-CoA synthetase 2, Long-chain-fatty-acid--CoA ligase 1, ACS1, LACS 1, Palmitoyl-CoA ligase 2, Phytanate--CoA ligase, FACL2, Arachidonate--CoA ligase, Long-chain fatty acid-CoA ligase 2, ACSL1, Acyl-CoA synthetase 1, Palmitoyl-CoA ligase 1, LACS1, LACS, LACS 2
Metabolic reprogramming in hepatocellular carcinoma: an integrated omics study of lipid pathways and their diagnostic potential., PMID:40500772
Therapy resistance in AML is mediated by cytoplasmic sequestration of the transcriptional repressor IRF2BP2., PMID:40475530
Transcriptomics characteristics and differentiation of subcutaneous adipose tissue among Huainan pigs and its hybrid genetic populations., PMID:40475027
A Novel Camel Milk-Derived Peptide LLPK Improves Glucose-Lipid Metabolism in db/db Mice via PPAR Signaling Pathway., PMID:40431433
Identification and Functional Validation of ACSL1 and FABP3 as Muscle-Related Genes Screened by Transcriptomics in Crossbred Duroc × Berkshire × Diannan Small-Eared Pigs., PMID:40428342
Ferroptosis and necroptosis may be involved in the formation and progression of hydrofluoric acid burn wounds: Results from an RNA-Seq analysis., PMID:40327971
Alstonia scholaris (L.) R. Br. ameliorated diabetic nephropathy through PPAR-δ pathway., PMID:40294665
Identification of mitophagy-related genes in patients with acute myocardial infarction., PMID:40287718
Methotrexate loaded extracellular vesicles attenuate periodontitis by suppressing ACSL1 and promoting anti-inflammatory macrophage., PMID:40245705
DNA Methylation Patterns Provide Insights into the Epigenetic Regulation of Intersex Formation in the Chinese Mitten Crab (Eriocheir sinensis)., PMID:40244073
C-type natriuretic peptide regulates lipid metabolism through a NPRB-PPAR pathway in the intramuscular and subcutaneous adipocytes in chickens., PMID:40234429
Stevia rebaudiana root polysaccharide modulates liver metabolism, bile acid, and gut microbiota improving HFD-induced NAFLD: Potential roles of ACSL1 and FADS2., PMID:40220428
TSPAN31 Activates Fatty Acid Metabolism and PI3K/AKT Pathway to Promote Tumor Progression in Breast Cancer., PMID:40135650
METTL3 promotes infantile pneumonia-induced lung injury by the m6A-TBL1XR1-ACSL1 axis., PMID:40117788
Nutrient deficiency-induced downregulation of SNX1 inhibits ferroptosis through PPARs-ACSL1/4 axis in colorectal cancer., PMID:40095264
Indole-3-propionic acid alleviates DSS-induced colitis in mice through macrophage glycolipid metabolism., PMID:40086057
Identification and functional validation of ACSL1 as a biomarker regulating ferroptosis in nucleus pulposus cell., PMID:40042449
Antifungal activity and mechanism of Phoebe bournei wood essential oil against two dermatophytes., PMID:39990148
Bioinformatics insights into ACSL1 and ACSL5: prognostic and immune roles in low-grade glioma., PMID:39924494
SERT-Deficient Mice Fed Western Diet Reveal Altered Metabolic and Pro-Inflammatory Responses of the Liver: A Link to Abnormal Behaviors., PMID:39862090
ACSL1 Aggravates Thromboinflammation by LPC/LPA Metabolic Axis in Hyperlipidemia Associated Myocardial Ischemia-Reperfusion Injury., PMID:39853712
Maternal high-fat diet alters the transcriptional rhythm in white adipose tissue of adult offspring., PMID:39826765
Ergosterol alleviates hepatic steatosis and insulin resistance via promoting fatty acid β-oxidation by activating mitochondrial ACSL1., PMID:39799570
MCL-1 regulates cellular transitions during oligodendrocyte development., PMID:39763750
Effects of moderate intensity exercise on liver metabolism in mice based on multi-omics analysis., PMID:39730655
Machine Learning Integration with Single-Cell Transcriptome Sequencing Datasets Reveals the Impact of Tumor-Associated Neutrophils on the Immune Microenvironment and Immunotherapy Outcomes in Gastric Cancer., PMID:39684426
Type I IFN induces long-chain acyl-CoA synthetase 1 to generate a phosphatidic acid reservoir for lipotoxic saturated fatty acids., PMID:39675509
Identification of lipid metabolism-related biomarkers and prognostic analysis in geriatric patients with sepsis., PMID:39616476
Research note: Increased lipid accumulation within broiler preadipocytes during differentiation in vitro at atmospheric oxygen tension., PMID:39566173
Flavonoids from Rhododendron nivale Hook. f ameliorate alcohol-associated liver disease via activating the PPARα signaling pathway., PMID:39556985
Regional and longitudinal dynamics of human milk protein components assessed by proteome analysis on a fast and robust micro-flow LC-MS/MS system., PMID:39550967
miRNA-148a-3p targets to regulate the lipid metabolism gene SOCS3 to reduce myocardial ischemia/reperfusion injury., PMID:39535526
FSH increases lipid droplet content by regulating the expression of genes related to lipid storage in Rat Sertoli cells., PMID:39490730
ACSL1 improves pulmonary fibrosis by reducing mitochondrial damage and activating PINK1/Parkin mediated mitophagy., PMID:39489819
ACSL1 positively regulates adipogenic differentiation., PMID:39442449
Rice Protein Peptides Alleviate Alcoholic Liver Disease via the PPARγ Signaling Pathway: Through Liver Metabolomics and Gut Microbiota Analysis., PMID:39406388
Hsa-circ-ACSL1 Enhances Apoptosis and Autophagy in Myocarditis Cardiomyocytes Through the miR-7-5p/XBP1 Axis., PMID:39378323
Cystathionine-γ-lyase contributes to tamoxifen resistance, and the compound I194496 alleviates this effect by inhibiting the PPARγ/ACSL1/STAT3 signalling pathway in oestrogen receptor-positive breast cancer., PMID:39362925
Transcriptomic Analysis of Cardiac Tissues in a Rodent Model of Coronary Microembolization., PMID:39345897
Acyl-CoA long-chain synthetase 1 (ACSL1) protects the endometrium from excess palmitic acid stress during decidualization., PMID:39343116
Combining Transcriptomics and Proteomics to Screen Candidate Genes Related to Bovine Birth Weight., PMID:39335340
Transcriptome and proteomic analysis reveal the protective mechanism of acupuncture on reproductive function in mice with asthenospermia., PMID:39286182
Sortilin-mediated translocation of mitochondrial ACSL1 impairs adipocyte thermogenesis and energy expenditure in male mice., PMID:39232011
Acyl-CoA Synthetase Long-Chain Isoenzymes in Kidney Diseases: Mechanistic Insights and Therapeutic Implications., PMID:39210707
Estrogenic Responsiveness of Brown Trout Primary Hepatocyte Spheroids to Environmental Levels of 17α-Ethinylestradiol., PMID:39189175
Discovering the lipid metabolism-related hub genes of HCC-treated samples with PPARα agonist through weighted correlation network analysis., PMID:39179766
shRNA-mediated down-regulation of Acsl1 reverses skeletal muscle insulin resistance in obese C57BL6/J mice., PMID:39178212
Empagliflozin improves aortic injury in obese mice by regulating fatty acid metabolism., PMID:39176252
The PRMT6/STAT1/ACSL1 axis promotes ferroptosis in diabetic nephropathy., PMID:39134684
Proteome Analysis Related to Unsaturated Fatty Acid Synthesis by Interfering with Bovine Adipocyte ACSL1 Gene., PMID:38929080
For research use only. Not for human or drug use.
