Catalog No.
YHD34601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Trp149-Pro365
Predicted molecular weight
27.24 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P19526
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Fucosyltransferase 1, FUT1, Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT1, Blood group H alpha 2-fucosyltransferase, HSC, H, Galactoside alpha-(1,2)-fucosyltransferase 1, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1, Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT1, Alpha(1,2)FT 1
Genetic analysis and protein modeling evaluation of a novel FUT1 variant c.683T>C (p.Met228Thr) in a Chinese individual with para-Bombay phenotype., PMID:40497798
Comprehensive Multi-Omics Analysis Identifies FUT1 as a Prognostic and Therapeutic Biomarker Across Pan-Cancer., PMID:40084262
N-glycan core tri-fucosylation requires Golgi α-mannosidase III activity that impacts nematode growth and behavior., PMID:39481603
Identification of two novel variants, c.-35A>T and c.[-35A>T, 725T>G], in the FUT1 gene in a patient exhibiting the para-Bombay phenotype., PMID:39473114
H Antigen expression modulates epidermal Keratinocyte Integrity and differentiation., PMID:39420441
Terminal α1,2-fucosylation of glycosphingolipids by FUT1 is a key regulator in early cell-fate decisions., PMID:39256596
Role of Long Intergenic Nonprotein-Coding RNA 00511 in Nod-Like Receptor Protein Pyrin Domain 3-Induced Chondrocyte Pyroptosis via the MicroRNA-9-5p/FUT1 Axis., PMID:38934781
Impact of fucosyltransferase 1-mediated epidermal blood group antigen H on anti-inflammatory response in atopic dermatitis., PMID:38840912
Detection and Analysis of Antidiarrheal Genes and Immune Factors in Various Shanghai Pig Breeds., PMID:38786002
Altered O-linked glycosylation in benign and malignant meningiomas., PMID:38274327
Fucosylation deficiency enhances imiquimod-induced psoriasis-like skin inflammation by promoting CXCL1 expression., PMID:38070583
Sec1 regulates intestinal mucosal immunity in a mouse model of inflammatory bowel disease., PMID:38066482
Splenocytes with fucosylation deficiency promote T cell proliferation and differentiation through thrombospondin-1 downregulation., PMID:37957948
FUT1 variants responsible for Bombay or para-Bombay phenotypes in a database., PMID:37838738
Dynamic alterations of the transcriptome-wide m6A methylome in cytogenetically normal acute myeloid leukaemia during initial diagnosis and relapse., PMID:37820824
Cloning, Expression, and Functional Characterization of FUT1, a Key Gene for Histo-Blood Group Antigens Synthesis in Crassostrea gigas., PMID:37232736
FUT1-mediated terminal fucosylation acts as a new target to attenuate renal fibrosis., PMID:37085770
Fucosyltransferases Regulated by Fusobacterium Nucleatum and Act as Novel Biomarkers in Colon Adenocarcinoma., PMID:36852302
Expanded Proteomic Survey of the Human Parasite Leishmania major Focusing on Changes in Null Mutants of the Golgi GDP-Mannose/Fucose/Arabinopyranose Transporter LPG2 and of the Mitochondrial Fucosyltransferase FUT1., PMID:36394313
Common and unique features of glycosylation and glycosyltransferases in African trypanosomes., PMID:36066312
The Eyelid Meibomian Gland Deficiency in Fucosyltransferase 1 Knockout Mice., PMID:36012728
A Comprehensive Prognostic Analysis of Tumor-Related Blood Group Antigens in Pan-Cancers Suggests That SEMA7A as a Novel Biomarker in Kidney Renal Clear Cell Carcinoma., PMID:35955933
Targeting Aberrantly Elevated Sialyl Lewis A as a Potential Therapy for Impaired Endometrial Selection Ability in Unexplained Recurrent Miscarriage., PMID:35837404
YY1-induced lncRNA XIST inhibits cartilage differentiation of BMSCs by binding with TAF15 to stabilizing FUT1 expression., PMID:35402663
Calreticulin Regulates β1-Integrin mRNA Stability in PC-3 Prostate Cancer Cells., PMID:35327448
Glycoproteomics of NOTCH1 EGF repeat fragments overexpressed with different glycosyltransferases in HEK293T cells reveals insights into O-GlcNAcylation of NOTCH1., PMID:35290457
Identification of a new allele of O-fucosyltransferase 1 involved in Drosophila intestinal stem cell regulation., PMID:34731235
RNA-Sequencing Based microRNA Expression Signature of Colorectal Cancer: The Impact of Oncogenic Targets Regulated by miR-490-3p., PMID:34576039
Partners in crime: The Lewis Y antigen and fucosyltransferase IV in Helicobacter pylori-induced gastric cancer., PMID:34571111
A broadly active fucosyltransferase LmjFUT1 whose mitochondrial localization and activity are essential in parasitic Leishmania., PMID:34385330
Glucose deprivation-induced aberrant FUT1-mediated fucosylation drives cancer stemness in hepatocellular carcinoma., PMID:33878034
The Importance of Sex in the Discovery of Colorectal Cancer Prognostic Biomarkers., PMID:33572952
Total Platelet Transcriptomics and Its Network Analysis by RNA-Seq and miRNA-Seq and PCA Application in Essential Thrombocythaemia., PMID:33227791
The alpha-1,2 fucosylated tubule system of DU145 prostate cancer cells is derived from a partially fragmented Golgi complex and its formation is actin-dependent., PMID:33065114
Monoclonal antibodies specific for podocalyxin expressed on human induced pluripotent stem cells., PMID:32912628
miR-5193, regulated by FUT1, suppresses proliferation and migration of ovarian cancer cells by targeting TRIM11., PMID:32823233
Changes in the host transcriptome and microbial metatranscriptome of the ileum of dairy calves subjected to artificial dosing of exogenous rumen contents., PMID:32567508
Altered expression of fucosylation pathway genes is associated with poor prognosis and tumor metastasis in non‑small cell lung cancer., PMID:31894325
Terminal fucose mediates progression of human cholangiocarcinoma through EGF/EGFR activation and the Akt/Erk signaling pathway., PMID:31754244
Glycosylation of Specific Notch EGF Repeats by O-Fut1 and Fringe Regulates Notch Signaling in Drosophila., PMID:31722217
The First Case of Para-Bombay Blood Type Encountered in a Korean Tertiary Hospital., PMID:31602828
Regular alteration of protein glycosylation in skeletal muscles of hibernating Daurian ground squirrels (Spermophilus dauricus)., PMID:31454680
Gene expression profiling reveals upregulated FUT1 and MYBPC1 in children with pancreaticobiliary maljunction., PMID:31365696
Effect of Mucine 4 and Fucosyltransferase 1 genetic variants on gut homoeostasis of growing healthy pigs., PMID:30734380
Cervical mucus sialic acid content determines the ability of frozen-thawed ram sperm to migrate through the cervix., PMID:30608906
Sequence analysis of α-(1, 2)-fucosyltransferase gene in nine Chinese individuals with Para-Bombay phenotype., PMID:30217757
Four Non-functional FUT1 Alleles Were Identified in Seven Chinese Individuals with Para-Bombay Phenotypes., PMID:30186784
Fucosylation genes as circulating biomarkers for lung cancer., PMID:30101373
ABO phenotype-protected reproduction based on human specific α1,2 L-fucosylation as explained by the Bombay type formation., PMID:30075871
The extended cytoplasmic tail of the human B4GALNT2 is critical for its Golgi targeting and post-Golgi sorting., PMID:30067891
For research use only. Not for human or drug use.
