Catalog No.
YHD09201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu159-Leu325
Predicted molecular weight
21.87 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P15169
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Anaphylatoxin inactivator, CPN, SCPN, CPN1, Carboxypeptidase N catalytic chain, Plasma carboxypeptidase B, Arginine carboxypeptidase, Carboxypeptidase N small subunit, ACBP, Lysine carboxypeptidase, Serum carboxypeptidase N, Carboxypeptidase N polypeptide 1, Kininase-1
Fission yeast Caprin protein is required for efficient heterochromatin establishment., PMID:40063661
Salmonella manipulates the host to drive pathogenicity via induction of interleukin 1β., PMID:38236896
Acute endoplasmic reticulum stress-induced mitochondria respiratory chain damage: The role of activated calpains., PMID:38197290
A cell wall-localized cytokinin/purine riboside nucleosidase is involved in apoplastic cytokinin metabolism in Oryza sativa., PMID:37639600
Identification of lncRNA-miRNA-mRNA Regulatory Network and Therapeutic Agents for Skin Aging by Bioinformatics Analysis., PMID:36719625
The mRNA vaccine BNT162b2 demonstrates impaired TH1 immunogenicity in human elders in vitro and aged mice in vivo., PMID:36597547
Searching for Genetic Biomarkers for Hereditary Angioedema Due to C1-Inhibitor Deficiency (C1-INH-HAE)., PMID:35873600
Impaired Kallikrein-Kinin System in COVID-19 Patients' Severity., PMID:35812405
The mitochondrial electron transport chain contributes to calpain 1 activation during ischemia-reperfusion., PMID:35550199
High Expression of RAI14 in Triple-Negative Breast Cancer Participates in Immune Recruitment and Implies Poor Prognosis Through Bioinformatics Analyses., PMID:35431930
Reversing mitochondrial defects in aged hearts: role of mitochondrial calpain activation., PMID:35044856
Calpain-mediated protein targets in cardiac mitochondria following ischemia-reperfusion., PMID:34997008
Reduced serum protease activity in Complex Regional Pain Syndrome: The impact of angiotensin-converting enzyme and carboxypeptidases., PMID:34392129
Comparative study on beneficial effects of vitamins B and D in attenuating doxorubicin induced cardiotoxicity in rats: Emphasis on calcium homeostasis., PMID:34029952
Serum Carboxypeptidase N1 Serves as a Potential Biomarker Complementing CA15-3 for Breast Cancer., PMID:32619179
Plasma-Based Proteomics Profiling of Patients with Hyperthyroidism after Antithyroid Treatment., PMID:32575434
PNPT1 and PCGF3 variants associated with angiotensin-converting enzyme inhibitor-induced cough: a nested case-control genome-wide study., PMID:32397904
Genome-wide meta-analysis identifies novel loci associated with age-related macular degeneration., PMID:32277175
Comparative Proteomic Investigation of Plasma Reveals Novel Potential Biomarker Groups for Acute Aortic Dissection., PMID:32256857
Endoplasmic reticulum stress-induced complex I defect: Central role of calcium overload., PMID:32061585
Inhibition of the ubiquitous calpains protects complex I activity and enables improved mitophagy in the heart following ischemia-reperfusion., PMID:31411917
Ssams2, a Gene Encoding GATA Transcription Factor, Is Required for Appressoria Formation and Chromosome Segregation in Sclerotinia sclerotiorum., PMID:30574138
Identification and characterization of a carboxypeptidase N1 from red lip mullet (Liza haematocheila); revealing its immune relevance., PMID:30300741
Whole-genome sequencing study of serum peptide levels: the Atherosclerosis Risk in Communities study., PMID:28854705
Fine-tune regulation of carboxypeptidase N1 controls vascular patterning during zebrafish development., PMID:28500283
Variation at HLA-DPB1 is associated with dermatomyositis in Chinese population., PMID:27153935
Profiling of Cross-Functional Peptidases Regulated Circulating Peptides in BRCA1 Mutant Breast Cancer., PMID:27058005
Does mouse embryo primordial germ cell activation start before implantation as suggested by single-cell transcriptomics dynamics?, PMID:26740066
Activation of mitochondrial calpain and increased cardiac injury: beyond AIF release., PMID:26637561
Selection of alkalotolerant and symbiotically efficient chickpea nodulating rhizobia from North-West Indo Gangetic Plains., PMID:26377641
A new genetic model for calcium induced autophagy and ER-stress in Drosophila photoreceptor cells., PMID:25664921
Two carboxypeptidase counterparts from rock bream (Oplegnathus fasciatus): molecular characterization, genomic arrangement and immune responses upon pathogenic stresses., PMID:25457548
Association of polymorphisms in GCKR and TRIB1 with nonalcoholic fatty liver disease and metabolic syndrome traits., PMID:24785259
Suppressor of K+ transport growth defect 1 (SKD1) interacts with RING-type ubiquitin ligase and sucrose non-fermenting 1-related protein kinase (SnRK1) in the halophyte ice plant., PMID:23580756
Toxicity and outcome of pelvic IMRT for node-positive prostate cancer., PMID:23053142
JC virus encephalopathy is associated with a novel agnoprotein-deletion JCV variant., PMID:22536439
Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough., PMID:21052031
Requirement of calcium binding, myristoylation, and protein-protein interaction for the Copine BON1 function in Arabidopsis., PMID:20634289
Antigenic group II chaperonin in Methanobrevibacter oralis may cross-react with human chaperonin CCT., PMID:20331799
Targeted disruption of the gene encoding the murine small subunit of carboxypeptidase N (CPN1) causes susceptibility to C5a anaphylatoxin-mediated shock., PMID:19414808
Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes., PMID:18940312
Evidence that the BONZAI1/COPINE1 protein is a calcium- and pathogen-responsive defense suppressor., PMID:18855102
The TIR-NB-LRR gene SNC1 is regulated at the transcript level by multiple factors., PMID:17977156
Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain., PMID:17157876
The C2 domain protein BAP1 negatively regulates defense responses in Arabidopsis., PMID:17018034
The BON/CPN gene family represses cell death and promotes cell growth in Arabidopsis., PMID:16367962
Transgenic expression of the von Willebrand A domain of the BONZAI 1/COPINE 1 protein triggers a lesion-mimic phenotype in Arabidopsis., PMID:15843967
Expression of the third complement component (C3) and carboxypeptidase N small subunit (CPN1) during mouse embryonic development., PMID:15177117
Carboxypeptidase N: a pleiotropic regulator of inflammation., PMID:14687935
Regulation of Arabidopsis COPINE 1 gene expression in response to pathogens and abiotic stimuli., PMID:12857819
For research use only. Not for human or drug use.
