Catalog No.
YHD02901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr4-Pro289
Predicted molecular weight
33.45 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P14061
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EDH17B1, Short chain dehydrogenase/reductase family 28C member 1, EDHB17, Placental 17-beta-hydroxysteroid dehydrogenase, SDR28C1, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, HSD17B1, 17-beta-HSD 1, E2DH, Estradiol 17-beta-dehydrogenase 1, EDH17B2, E17KSR, 17-beta-hydroxysteroid dehydrogenase type 1
Daidzein-rich isoflavone aglycones inhibit 17β-hydroxysteroid dehydrogenase 1 and increase estrogen sulfotransferase in endometriosis., PMID:40497318
Transcriptome and proteome profile analysis of the regulation of chicken ovarian development., PMID:40466268
HSD17B1-mediated trophoblast differentiation lowers estrogen levels in early-onset preeclampsia., PMID:40394177
Impact of Missense Variants on the Structure and Function of Polycystic Ovary Syndrome-Associated HSD17B1 Gene., PMID:40257693
Transcriptomic analysis identifies CXCL12 as a novel candidate gene for litter size in rabbits., PMID:40211853
Benzophenone UV-filters: Inhibition on human and rat 17β-hydroxysteroid dehydrogenase 1 - insights from 3D-QSAR and docking studies., PMID:40122306
Biological and therapeutic implications of sex hormone-related gene clustering in testicular cancer., PMID:40011822
Exposure-effect of PFOS and PFOA on lung function: An integrated approach with epidemiological, cellular, and animal studies., PMID:39983955
Study on the mechanism of the Chinese herbal pair Banxia-Chenpi in ameliorating polycystic ovary syndrome based on the CYP17A1 gene., PMID:39961422
Dietary DHA Regulated the Androgen Production in Male Chinese Tongue Sole Cynoglossus semilaevis., PMID:39949363
A Homozygous Variant in HSD17B1 Identified in Women With Poor Ovarian Response., PMID:39840549
Comparative transcriptome analysis identified genes involved in ovarian development in Takifugu rubripes., PMID:39736263
Piperazine ferulate impact on diabetes-induced testicular dysfunction: unveiling genetic insights, MAPK/ERK/JNK pathways, and TGF-β signaling., PMID:39671097
Gonadal transcriptome analysis of Opsariichthys bidens reveals sex-associated genes., PMID:39667087
Proof-of-Concept for Long-Term Human Endometrial Epithelial Organoids in Modeling Menstrual Cycle Responses., PMID:39513919
Gonadal Development and Differentiation of Hybrid F1 Line of Ctenopharyngodon idella (♀) × Squaliobarbus curriculus (♂)., PMID:39408892
The Role of MALAT1 in Regulating the Proangiogenic Functions, Invasion, and Migration of Trophoblasts in Selective Fetal Growth Restriction., PMID:39199376
MTHFR as a Novel Candidate Marker for Litter Size in Rabbits., PMID:38998044
Steroid metabolism and hormonal dynamics in normal and malignant ovaries., PMID:38994724
Inhibitory effects of parabens on human and rat 17β-hydroxysteroid dehydrogenase 1: Mechanisms of action and impact on hormone synthesis., PMID:38986729
A Study on the Protective Impact of Resveratrol on Liver Damage in Rats with Obstructive Jaundice., PMID:38910417
Identification of Hydroxysteroid Dehydrogenase Type 1 As a Potential Bladder Tumor Marker., PMID:38850011
The Expression of Adipogenic Marker Is Significantly Increased in Estrogen-Treated Lipedema Adipocytes Differentiated from Adipose Stem Cells In Vitro., PMID:38791004
Serum hydroxysteroid (17beta) dehydrogenase 1 concentration in pregnant women correlates with pregnancy-associated plasma protein A but does not serve as an independent marker for preeclampsia†., PMID:38780059
Molecular characterization and expression profile of the ALDH1A1 gene and its functions in yak luteal cells., PMID:38697014
ERβ Regulation of Indian Hedgehog Expression in the First Wave of Ovarian Follicles., PMID:38607081
4D label-free quantitative proteomic analysis identifies CRABP1 as a novel candidate gene for litter size in rabbits†., PMID:38478424
Microbiota modulates the steroid response to acute immune stress in male mice., PMID:38361932
Chlorothalonil as a potential endocrine disruptor in male zebrafish (Danio rerio): Impact on the hypothalamus-pituitary-gonad axis and sperm quality., PMID:38340991
17β-Hydroxysteroid dehydrogenases types 1 and 2: Enzymatic assays based on radiometric and mass-spectrometric detection., PMID:37802571
Developmental toxicity and estrogenicity of glyphosate in zebrafish in vivo and in silico studies., PMID:37758082
CRISPR/Cas9-mediated activation of NR5A1 steers female human embryonic stem cell-derived bipotential gonadal-like cells towards a steroidogenic cell fate., PMID:37726790
LH/hCG Regulation of Circular RNA in Mural Granulosa Cells during the Periovulatory Period in Mice., PMID:37685885
Steroidogenic activity of liposomal methylated resveratrol analog 3,4,5,4'-tetramethoxystilbene (DMU-212) in human luteinized granulosa cells in a primary three-dimensional in vitro model., PMID:37572199
Abnormal DNA methylation within genes of the steroidogenesis pathway two years after paediatric critical illness and association with stunted growth in height further in time., PMID:37468957
Molecular cloning and characterization of STC1 gene and its functional analyses in yak (Bos grunniens) cumulus granulosa cells., PMID:37354862
The Placenta-A New Source of Bile Acids during Healthy Pregnancy? First Results of a Gene Expression Study in Humans and Mice., PMID:37298459
Atretic preovulatory follicles could be precursors of ovarian lutein cysts in the pig., PMID:37173342
Spheroid formation and luteinization of granulosa cells of felids in a long-term 3D culture., PMID:37079952
An integrated approach of network pharmacology, molecular docking, and experimental verification uncovers kaempferol as the effective modulator of HSD17B1 for treatment of endometrial cancer., PMID:36932403
Landscape of pathogenic mutations in premature ovarian insufficiency., PMID:36732629
New insights into the substrate inhibition of human 17β-hydroxysteroid dehydrogenase type 1., PMID:36634828
Screening of high-risk deleterious missense variations in the CYP1B1 gene implicated in the pathogenesis of primary congenital glaucoma: A comprehensive in silico approach., PMID:36518267
Investigation of biomarkers in Endometriosis-associated infertility: Systematic Review., PMID:36477241
Identification of genes related to sexual differentiation and sterility in embryonic gonads of Mule ducks by transcriptome analysis., PMID:36386800
Analysis of PPP1R11 expression in granulosa cells during developmental follicles of yak and its effects on cell function., PMID:36178063
The aphrodisiac potential of β-cyclodextrin-curcumin via stimulating cAMP-PKA pathway in testicular Leydig cells., PMID:35995927
Differential proteomics analysis of JEG-3 and JAR placental cell models and the effect of androgen treatment., PMID:35690242
Site-Specific Regulation of Sulfatase and Aromatase Pathways for Estrogen Production in Endometriosis., PMID:35591944
Overexpression of Human Estrogen Biosynthetic Enzyme Hydroxysteroid (17beta) Dehydrogenase Type 1 Induces Adenomyosis-like Phenotype in Transgenic Mice., PMID:35563206
For research use only. Not for human or drug use.
