Catalog No.
YHC85001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile521-Pro772
Predicted molecular weight
30.04 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P11047
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Laminin-7 subunit gamma, Laminin-1 subunit gamma, Laminin subunit gamma-1, Laminin-10 subunit gamma, Laminin-2 subunit gamma, S-laminin subunit gamma, LAMC1, Laminin-11 subunit gamma, Laminin-3 subunit gamma, S-LAM gamma, Laminin-6 subunit gamma, Laminin-9 subunit gamma, Laminin-4 subunit gamma, Laminin-8 subunit gamma, LAMB2, Laminin B2 chain, laminin 1, laminin 111, EHS laminin, laminin 2, laminin 211, merosin, laminin 3, laminin 121, S laminin, laminin 4, laminin 221, S merosin, laminin 6, laminin 311, K laminin, laminin 7, laminin 321, KS laminin, laminin 8, laminin 411, laminin 9, laminin 421, laminin 10, laminin 511, laminin 11, laminin 521
Anti-Laminin β4 IgG Drives Tissue Damage in Anti-p200 Pemphigoid and Shows Interactions with Laminin α3 and γ1/2 Chains., PMID:39320300
Phosphorylation mapping of laminin γ1-chain: Kinases, functional interaction sequences, and phosphorylationinterfering cancer mutations., PMID:39311033
Anti-p200 Pemphigoid Mimicking Acquired Reactive Perforating Collagenosis., PMID:39248294
Lamc1 promotes osteogenic differentiation and inhibits adipogenic differentiation of bone marrow-derived mesenchymal stem cells., PMID:39179716
Expression of the laminin genes family and its relationship to prognosis in pancreatic carcinoma., PMID:39039002
HIF-1α-mediated LAMC1 overexpression is an unfavorable predictor of prognosis for glioma patients: evidence from pan-cancer analysis and validation experiments., PMID:38678297
Oligodendrocyte-derived laminin-γ1 regulates the blood-brain barrier and CNS myelination in mice., PMID:38635399
Successful treatment with guselkumab of anti-p200 pemphigoid associated with plaque psoriasis., PMID:38593343
A case of anti-laminin γ1 (p200) pemphigoid developed after dipeptidyl peptidase-4 inhibitor administration., PMID:38214494
NUDT21 alters glioma migration through differential alternative polyadenylation of LAMC1., PMID:37389756
Hsa_circ_0005085 may suppress cutaneous squamous cell carcinoma growth and metastasis through targeting the miR-186-5p/LAMC1 axis., PMID:37357644
Transcriptome analyses reveal differentially expressed genes associated with development of the palatal organ in bighead carp (Hypophthalmichthys nobilis)., PMID:36990038
Circ_0124208 Promotes the Progression of Hepatocellular Carcinoma by Regulating the miR-338-3p/LAMC1 Axis., PMID:36780058
The Intriguing Links between Psoriasis and Bullous Pemphigoid., PMID:36615129
Whole exome sequencing identifies KIF26B, LIFR and LAMC1 mutations in familial vesicoureteral reflux., PMID:36417404
LncRNA TM4SF19-AS1 exacerbates cell proliferation, migration, invasion, and EMT in head and neck squamous cell carcinoma via enhancing LAMC1 expression., PMID:36411963
Comprehensive analysis of LAMC1 expression and prognostic value in kidney renal papillary cell carcinoma and clear cell carcinoma., PMID:36188228
Effects of lipoteichoic and arachidonic acids on the immune-regulatory mechanism of bovine mammary epithelial cells using multi-omics analysis., PMID:36090174
Evaluation of miR-429 as a novel serum biomarker for pancreatic ductal adenocarcinoma and analysis its tumor suppressor function and target genes., PMID:35856354
A case of anti-laminin gamma-1 (p200) pemphigoid with bullous lesions on the lips, hands and feet showing antibodies to desmoglein 1., PMID:35665215
LAMC1-mediated preadipocytes differentiation promoted peritoneum pre-metastatic niche formation and gastric cancer metastasis., PMID:35541892
Association of miRNA targetome variants in LAMC1 and GNB3 genes with colorectal cancer and obesity., PMID:35373932
When Bullous Pemphigoid Is Not Bullous Pemphigoid: The Importance of Going Beyond Direct Immunofluorescence., PMID:35308677
A case report of anti-P200 pemphigoid following COVID-19 vaccination., PMID:35308065
Fuchs Endothelial Corneal Dystrophy associated risk variant, rs3768617 in LAMC1 shows allele specific binding of GFI1B., PMID:35031421
PSMA3-AS1 induced by transcription factor PAX5 promotes cholangiocarcinoma proliferation, migration and invasion by sponging miR-376a-3p to up-regulate LAMC1., PMID:35022330
The long non-coding RNA ASMTL-AS1 promotes hepatocellular carcinoma progression by sponging miR-1343-3p that suppresses LAMC1 (laminin subunit gamma 1)., PMID:34859735
A novel regQTL-SNP and the risk of lung cancer: a multi-dimensional study., PMID:34596730
A Serological Biomarker of Laminin Gamma 1 Chain Degradation Reflects Altered Basement Membrane Remodeling in Crohn's Disease and DSS Colitis., PMID:34561759
Effects of long-term immobilisation on endomysium of the soleus muscle in humans., PMID:34387385
LAMC1 upregulation via TGFβ induces inflammatory cancer-associated fibroblasts in esophageal squamous cell carcinoma via NF-κB-CXCL1-STAT3., PMID:34218518
Structural mechanism of laminin recognition by integrin., PMID:34188035
Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry., PMID:34158478
LAMC1 is related to the poor prognosis of patients with gastric cancer and facilitates cancer cell malignancies., PMID:33884884
Circular ribonucleic acid nei-like deoxyribonucleic acid glycosylase 3 governs the microribonucleic acid -3150b-3p/laminin subunit gamma 1 network to partially promote the development of hepatocellular carcinoma., PMID:33738908
Refractory bullous pemphigoid with IgE anti-BP230 and IgG anti-p200 antibodies successfully treated with omalizumab., PMID:33478824
Synthesis and biological evaluation of modified laminin peptide (N2S2-KDP) with enhanced affinity for neuronal growth and targeted molecular imaging (SPECT)., PMID:33293057
Acute changes in nidogen-1 expression in the epidermal basement membrane of a 3-dimensional cultured human skin model after ultraviolet B irradiation., PMID:32920911
Extracellular Matrix Injury of Kidney Allografts in Antibody-Mediated Rejection: A Proteomics Study., PMID:32900843
Integrin subunit β1 and laminin γ1 chain expression: a potential prognostic biomarker in cervical cancer., PMID:32845182
Noninvasive Assessment of Fibrosis Following Ischemia/Reperfusion Injury in Rodents Utilizing Na Magnetic Resonance Imaging., PMID:32824113
Serologic characterization of anti-p200 pemphigoid: Epitope spreading as a common phenomenon., PMID:32711089
Abnormal Endothelial Gene Expression Associated With Early Coronary Atherosclerosis., PMID:32673514
Common variants in LAMC1 confer risk for pelvic organ prolapse in Chinese population., PMID:32635941
Laminin is the ECM niche for trophoblast stem cells., PMID:31937556
Nodular formation in anti-laminin γ1 pemphigoid., PMID:31916269
LAMC1 is a prognostic factor and a potential therapeutic target in endometrial cancer., PMID:31912669
The Adult Murine Intestine is Dependent on Constitutive Laminin-γ1 Synthesis., PMID:31848396
Atypical anti-p200 pemphigoid with nail involvement and blisters over the joints., PMID:31846162
Anti-p200 Pemphigoid: A Systematic Review., PMID:31695695
For research use only. Not for human or drug use.
