Catalog No.
YHC27801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp749-Thr956
Predicted molecular weight
24.96 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P07814
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EPRS, PARS, EPRS1, Bifunctional aminoacyl-tRNA synthetase, GLNS, QARS, QPRS, Glutamyl-tRNA synthetase, Glutamatyl-prolyl-tRNA synthetase, Prolyl-tRNA synthetase, Bifunctional glutamate/proline--tRNA ligase, Cell proliferation-inducing gene 32 protein, GluRS
EPRS1-mediated fibroblast activation and mitochondrial dysfunction promote kidney fibrosis., PMID:39623092
Identification of TFRC as a biomarker for pulmonary arterial hypertension based on bioinformatics and experimental verification., PMID:39097701
AKT-dependent nuclear localization of EPRS1 activates PARP1 in breast cancer cells., PMID:39012819
Homozygous EPRS1 missense variant causing hypomyelinating leukodystrophy-15 alters variant-distal mRNA m6A site accessibility., PMID:38769304
Targeting immune cell glutamyl-prolyl-transfer RNA synthetase 1 (EPRS1) to prevent fibrosis after tubulointerstitial nephritis., PMID:38642990
Glutamyl-prolyl-tRNA synthetase (EPRS1) drives tubulointerstitial nephritis-induced fibrosis by enhancing T cell proliferation and activity., PMID:38320721
Cardiomyocyte-Specific Loss of Glutamyl-prolyl-tRNA Synthetase Leads to Disturbed Protein Homeostasis and Dilated Cardiomyopathy., PMID:38201239
Cardiomyocyte-specific Loss of Glutamyl-prolyl-tRNA Synthetase Leads to Disturbed Protein Homeostasis and Dilated Cardiomyopathy., PMID:37790482
Phosphocode-dependent glutamyl-prolyl-tRNA synthetase 1 signaling in immunity, metabolism, and disease., PMID:37779151
A viral pan-end RNA element and host complex define a SARS-CoV-2 regulon., PMID:37296097
EPRS1 Controls the TGF-β Signaling Pathway via Interaction with TβRI in Hepatic Stellate Cell., PMID:37154023
EPRS1 correlates with malignant progression in hepatocellular carcinoma., PMID:37138286
Aminoacylation-defective bi-allelic mutations in human EPRS1 associated with psychomotor developmental delay, epilepsy, and deafness., PMID:36411955
Glutamyl-prolyl-tRNA synthetase 1 coordinates early endosomal anti-inflammatory AKT signaling., PMID:36309524
Disease-associated mutations in a bifunctional aminoacyl-tRNA synthetase gene elicit the integrated stress response., PMID:34537243
Hypomyelinating Leukodystrophy 15 (HLD15)-Associated Mutation of EPRS1 Leads to Its Polymeric Aggregation in Rab7-Positive Vesicle Structures, Inhibiting Oligodendroglial Cell Morphological Differentiation., PMID:33805425
Cell-based analysis of pairwise interactions between the components of the multi-tRNA synthetase complex., PMID:32539228
For research use only. Not for human or drug use.
