Catalog No.
YHC12501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp672-Val711
Predicted molecular weight
31.17 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P05067
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
AICD-57, A4, Beta-CTF, Protease nexin-II, Gamma-CTF(50), ABPP, S-APP-beta, APP, Abeta40, Abeta42, AID(59), Amyloid intracellular domain 59, AID(57), S-APP-alpha, Gamma-CTF(59), Beta-secretase C-terminal fragment, Amyloid-beta precursor protein, Amyloid precursor protein, Beta-APP42, PreA4, Alzheimer disease amyloid protein, APPI, PN-II, AICD-59, Alpha-secretase C-terminal fragment, Amyloid-beta A4 protein, Amyloid intracellular domain 57, CVAP, Amyloid intracellular domain 50, Beta-APP40, AD1, Cerebral vascular amyloid peptide, AID(50), Alpha-CTF, Gamma-CTF(57), AICD-50
The amyloid precursor family of proteins in excitatory neurons are essential for regulating cortico-hippocampal circuit dynamics in vivo., PMID:40512617
Iron-Mediated Overexpression of Amyloid Precursor Protein via Iron Responsive mRNA in Alzheimer's Disease., PMID:40508094
Relative Validity of the Food Recording Smartphone App Libro in Young People Vulnerable to Eating Disorder: A Preliminary Cross-Over Study., PMID:40507092
Teenagers with Obesity at the Gym: Recommendations for Physical Activity, Diet, and Supplementation-A Narrative Review., PMID:40507066
A Community-Based Mixed-Methods Study: Fish Bycatch Protein Supplementation as a Sustainable Solution for Child Malnutrition in Bengaluru, India., PMID:40507020
Synaptic Vesicle Glycoprotein 2A Slows down Amyloidogenic Processing of Amyloid Precursor Protein via Regulating Its Intracellular Trafficking., PMID:40506382
Amyloid precursor protein carboxy-terminal fragments as catalyzers of endolysosomal dysfunction in Alzheimer's disease., PMID:40506325
Combating multiple aetiologies of Alzheimer's disease to rescue behavioural deficits., PMID:40502821
PTP1B inhibition promotes microglial phagocytosis in Alzheimer's disease models by enhancing SYK signaling., PMID:40501708
Transepithelial transport and mechanism of pyrethroids across Caco-2 cells mediated by transporters., PMID:40500064
Beyond DNA damage response: Immunomodulatory attributes of CHEK2 in solid tumors., PMID:40492861
Characterization of transcriptomic changes in the neurovascular unit of Alzheimiers transgenic mouse models using digital spatial profiling., PMID:40492192
β-Amyloid as a new target to suppress tonic PTH hypersecretion in primary hyperparathyroidism., PMID:40492090
Structural and techno-functional characteristics of protein from the by-product of virgin coconut oil produced by centrifugation using coconut milk., PMID:40491708
Proposed Therapeutic Strategy to Combat Alzheimer's Disease by Targeting Beta and Gamma Secretases., PMID:40491367
AP2A1 activates Rab7 to promote axonal autophagosome transport and slow the progression of Alzheimer's disease., PMID:40490761
The Role of Sirt1 in Regulating Inflammatory Cytokines and Oxidative Stress in the Transition Mechanism from Depressive Disorder to Alzheimer's Disease., PMID:40490662
Radiofluorination of 2-Arylquinolin-4-yl Oxypropanamide Derivatives for TSPO Imaging in Neuroinflammatory Murine, Nonhuman Primates, and Human Brain Autoradiography with Insensitivity to the rs6971 Polymorphism., PMID:40489695
Benchmarking AlphaMissense pathogenicity predictions against APP, PSEN1, and PSEN2 variants of unknown significance., PMID:40486492
Ageing Signatures and Disturbed Muscle Regeneration in Muscle Proteome of Inclusion Body Myositis., PMID:40485189
A Novel Aβ B-cell epitope Vaccine, Aβ1-10 with carrier protein OVA and KLH reduce Aβ-induced neuroinflammation mediated neuropathology in mouse model of Alzheimer's disease., PMID:40484150
Exploration of Asparagus racemosus Willd for Alzheimer's Disease Through Integrated Metabolomics and Network Pharmacology Analyses Targeting BACE1 Protein., PMID:40483633
Unraveling novel mechanisms of ATP-Binding cassette (ABC) transporter in insulin Resistance-induced amyloidogenesis., PMID:40482009
Soluble VCAM-1 may serve as a pharmacodynamic CSF marker to monitor BACE2 activity in non-human primates., PMID:40480341
The Value of Neutrophil Cell Population Data Parameters as Markers of Systemic Inflammation in Dogs and Cats., PMID:40476643
Amyloid-beta deposition and reduced drainage at the cribriform plate lymphatics in APP/PS1 mouse model of Alzheimer's Disease., PMID:40475486
Gelsolin Facilitates Estrogen Receptor Beta Nuclear Translocation and Transcriptional Repression of Genes Associated with Alzheimer Disease., PMID:40475329
Cryoelectrospun elastin-alginate scaffolds as potential cell delivery vehicles for mesenchymal stromal cell therapy., PMID:40473688
The UNC5C T835M mutation associated with Alzheimer's disease leads to neurodegeneration involving oxidative stress and hippocampal atrophy in aged mice., PMID:40468412
Chronic social isolation-unpredictable stress induces early-onset cognitive deficits and exacerbates Aβ accumulation in the 5xFAD mouse model of Alzheimer's disease., PMID:40467855
Hampered AMPK-ULK1 cascade in Alzheimer's disease (AD) instigates mitochondria dysfunctions and AD-related alterations which are alleviated by metformin., PMID:40457477
Spatial navigation deficits in early Alzheimer's disease: the role of biomarkers and APOE genotype., PMID:40456910
Impaired Cognitive Flexibility With Preserved Learning in an Amyloid Precursor Protein Knock-In Mouse Model of Amyloidopathy., PMID:40455650
Neuroprotective Effects of Tectoridin in H2O2-Induced Oxidative Stress and an Amyloid-Infused Rat Model of Alzheimer's Disease., PMID:40455354
Anti-pyroglutamate-3 Aβ immunotherapy engages microglia and inhibits amyloid accumulation in transgenic mouse models of Aβ amyloidosis., PMID:40455292
Harnessing miRNA dynamics in HIV-1-infected macrophages: Unveiling new targeted therapeutics using systems biology., PMID:40453371
Investigation of differentiation conditions for canine duodenum, upper jejunum, and ileum crypt-derived cells for drug transport and metabolism., PMID:40450898
Early transcriptional and cellular abnormalities in choroid plexus of a mouse model of Alzheimer's disease., PMID:40450296
Atmospheric pressure plasma treatment increases the antioxidant capacity of the serum in vitro., PMID:40450058
Angiopep-2 modified naringin nanoparticles for Alzheimer's disease therapy overcoming BBB., PMID:40448955
Chronic Exercise Protects Against Cognitive Deficits in an Alzheimer's Disease Model by Enhancing Autophagy and Reducing Mitochondrial Abnormalities., PMID:40448811
From genetic roots to recent advancements in gene therapy targeting amyloid beta in Alzheimer's disease., PMID:40448320
Inflammatory response after stroke-A clinical observation study., PMID:40447994
Genetics and Epigenetics of Alzheimer's Disease: Understanding Pathogenesis and Exploring Therapeutic Potential., PMID:40447964
Synthesis of substrate peptides incorporating non-natural amino acids and screening study using BACE1., PMID:40447163
Weissella confusa Attenuates Cognitive Deficits in Alzheimer's Disease by Reducing Oxidative Stress Via the SIRT1/PGC-1α Signaling Pathway., PMID:40445426
Metabolomics and network pharmacology based study of the potential of Brassica rapa L. extract BREE-Ea for the treatment of Alzheimer's disease., PMID:40445088
Chronic administration of prebiotics and probiotics prevent pathophysiological hallmarks of Alzheimer's disease in the cortex of APP/PS1 mice., PMID:40444050
Impaired insulin receptor function alters psychiatric behaviors without affecting circadian rhythms in a mouse model of Alzheimer's disease., PMID:40443027
Acute targeting of N-terminal tau protein has long-lasting beneficial effects in Tg2576 APP/Aβ mouse model by reducing cognitive impairment, cerebral Aβ-amyloidosis, synaptic remodeling and microgliosis later in life., PMID:40442822
For research use only. Not for human or drug use.
