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Recombinant SARS-CoV-2 ORF3b Protein, N-His-SUMO

Catalog #:   YVV03401 Specific References (29) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P0DTF1
Protein length: Met1-Val22
Overview

Catalog No.

YVV03401

Expression system

E. coli

Species

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Protein length

Met1-Val22

Predicted molecular weight

18.16 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P0DTF1

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

ORF3b protein, ORF3b

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant SARS-CoV-2 ORF3b protein
References

Induction of the Inflammasome by the SARS-CoV-2 Accessory Protein ORF9b, Abrogated by Small-Molecule ORF9b Homodimerization Inhibitors., PMID:39902616

Involvement of SARS-CoV-2 accessory proteins in immunopathogenesis., PMID:38837257

Computational investigation of the inhibitory interaction of IRF3 and SARS-CoV-2 accessory protein ORF3b., PMID:38640732

Real-world COVID-19 vaccine effectiveness against the Omicron BA.2 variant in a SARS-CoV-2 infection-naive population., PMID:36652990

The role of SARS-CoV-2 accessory proteins in immune evasion., PMID:36265309

Roles and functions of SARS-CoV-2 proteins in host immune evasion., PMID:36003396

Development of Monoclonal Antibodies to Detect for SARS-CoV-2 Proteins., PMID:35405107

Genomic evolution of the Coronaviridae family., PMID:35398776

Anti-SARS-CoV-2 IgG responses are powerful predicting signatures for the outcome of COVID-19 patients., PMID:35116173

Target genes used for biosensor development in COVID-19 diagnosis., PMID:34974265

Production of Proteins of the SARS-CoV-2 Proteome for Drug Discovery., PMID:34337272

SARS-CoV-2 Accessory Proteins in Viral Pathogenesis: Knowns and Unknowns., PMID:34305949

Antibody landscape against SARS-CoV-2 reveals significant differences between non-structural/accessory and structural proteins., PMID:34242574

Selinexor, a novel selective inhibitor of nuclear export, reduces SARS-CoV-2 infection and protects the respiratory system in vivo., PMID:34157321

Critical Determinants of Cytokine Storm and Type I Interferon Response in COVID-19 Pathogenesis., PMID:33980688

Systematizing the genomic order and relatedness in the open reading frames (ORFs) of the coronaviruses., PMID:33848683

Conflicting and ambiguous names of overlapping ORFs in the SARS-CoV-2 genome: A homology-based resolution., PMID:33774510

Unification and extensive diversification of M/Orf3-related ion channel proteins in coronaviruses and other nidoviruses., PMID:33692906

Protein sequence models for prediction and comparative analysis of the SARS-CoV-2 -human interactome., PMID:33691013

The SARS-CoV-2 antibody landscape is lower in magnitude for structural proteins, diversified for accessory proteins and stable long-term in children., PMID:33655259

Loss of orf3b in the circulating SARS-CoV-2 strains., PMID:33205709

Unification of the M/ORF3-related proteins points to a diversified role for ion conductance in pathogenesis of coronaviruses and other nidoviruses., PMID:33200132

SARS-CoV-2-specific virulence factors in COVID-19., PMID:33085084

Dynamically evolving novel overlapping gene as a factor in the SARS-CoV-2 pandemic., PMID:33001029

SARS-CoV-2 ORF3b Is a Potent Interferon Antagonist Whose Activity Is Increased by a Naturally Occurring Elongation Variant., PMID:32941788

Type I Interferon Susceptibility Distinguishes SARS-CoV-2 from SARS-CoV., PMID:32938761

Characterization of accessory genes in coronavirus genomes., PMID:32854725

ORF8 and ORF3b antibodies are accurate serological markers of early and late SARS-CoV-2 infection., PMID:32807944

Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan., PMID:31987001

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Recombinant SARS-CoV-2 ORF3b Protein, N-His-SUMO [YVV03401]
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