Catalog No.
EVV00103
Expression system
Mammalian Cells
Species
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Protein length
Gln14-Gln1208
Predicted molecular weight
140.11 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P0DTC2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Spike glycoprotein, S glycoprotein, E2, Peplomer protein, Spike protein S1, Spike protein S2, Spike protein S2', S
Dynamic ensembles of SARS-CoV-2 N-protein reveal head-to-head coiled-coil-driven oligomerization and phase separation., PMID:40503686
Modulation of SARS-CoV-2 spike binding to ACE2 through conformational selection., PMID:40494932
Antigen persistence and TLR stimulation contribute to induction of a durable HIV-1-specific neutralizing antibody response., PMID:40461490
A recurrent neural network for soft sensor development using CHO stable pools in fed-batch process for SARS-CoV-2 spike protein production as a vaccine antigen., PMID:40454837
Salvianolic acid A acts as a herpes simplex virus dual inhibitor by blocking glycoprotein B-mediated adsorption and membrane fusion., PMID:40450985
Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that clamp the spike at its base., PMID:40447603
A combined digital microfluidic test for assessing infection and immunity status for viral disease in saliva., PMID:40423685
Comprehensive analysis of human coronavirus antibody responses in ICU and non-ICU COVID-19 patients reveals IgG3 against SARS-CoV-2 spike protein as a key biomarker of disease severity., PMID:40359129
The LDL receptor-related protein 1 (LRP1) facilitates ACE2-mediated endocytosis of SARS-CoV2 spike protein-containing pseudovirions., PMID:40349772
Integrating immune library probing with structure-based computational design to develop potent neutralizing nanobodies against emerging SARS-CoV-2 variants., PMID:40329514
SARS-CoV-2 spike protein: structure, viral entry and variants., PMID:40328900
Dynamics of SARS-CoV-2 Spike Receptor-Binding Domain-Targeted Specific Peripheral Memory B Cells in Patients With End-Stage Chronic Kidney Disease Undergoing Replacement Therapy Following COVID-19 Vaccination., PMID:40326950
Human coronavirus HKU1 spike structures reveal the basis for sialoglycan specificity and carbohydrate-promoted conformational changes., PMID:40324974
Self-Assembly of Nanogold Triplets on Trimeric Viral Proteins for Infectious Disease Diagnosis., PMID:40323304
Identification of a nanobody able to catalyze the destruction of the spike-trimer of SARS-CoV-2., PMID:40317451
Inclusion of a retroviral protease enhances the immunogenicity of VLP-forming mRNA vaccines against HIV-1 or SARS-CoV-2 in mice., PMID:40305570
Dual-Locking the SARS-CoV-2 Spike Trimer: An Amphipathic Molecular "Bolt" Stabilizes Conserved Druggable Interfaces for Coronavirus Inhibition., PMID:40285637
Infectivity and structure of SARS-CoV-2 after hydrogen peroxide treatment., PMID:40257280
Using Nano-Luciferase Binary (NanoBiT) Technology to Assess the Interaction Between Viral Spike Protein and Angiotensin-Converting Enzyme II by Aptamers., PMID:40227272
Modifying the glycosylation profile of SARS-CoV-2 spike-based subunit vaccines alters focusing of the humoral immune response in a mouse model., PMID:40217109
RBD-depleted SARS-CoV-2 spike generates protective immunity in cynomolgus macaques., PMID:40159504
SARS CoV-2 spike adopts distinct conformational ensembles in situ., PMID:40093071
SARS-CoV-2 serotyping based on spike antigenicity and its implications for host immune evasion., PMID:40080947
SARS-CoV-2 spike peptide analysis reveals a highly conserved region that elicits potentially pathogenic autoantibodies: implications to pan-coronavirus vaccine development., PMID:40070822
Structural and Conformational Impact of Deleterious Spike Protein Mutations in SARS-CoV-2 Omicron Lineages., PMID:40060440
A bivalent spike-targeting nanobody with anti-sarbecovirus activity., PMID:40059135
Potent and broadly neutralizing antibodies against sarbecoviruses elicited by single ancestral SARS-CoV-2 infection., PMID:40050417
Structure and dynamics of Alpha B.1.1.7 SARS-CoV-2 S-protein in complex with Fab of neutralizing antibody REGN10987., PMID:40043614
LNP-RNA-mediated antigen presentation leverages SARS-CoV-2-specific immunity for cancer treatment., PMID:40038251
Comparative efficacy of leading COVID-19 vaccines: A network meta-analysis., PMID:40036106
A recombinant protein vaccine induces protective immunity against SARS-CoV-2 JN.1 and XBB-lineage subvariants., PMID:40000611
Biomimetic Molecularly Imprinted Nanogels for the Recognition of Spike Glycoproteins., PMID:39961804
Preclinical evaluation of the RBD-Trimeric vaccine: A novel approach to strengthening biotechnological sovereignty in developing countries against SARS-CoV-2 variants., PMID:39954796
Structural characterization of influenza group 1 chimeric hemagglutinins as broad vaccine immunogens., PMID:39937865
Enhancing the solubility of SARS-CoV-2 inhibitors to increase future prospects for clinical development., PMID:39902960
Comparative Analysis of Machine Learning Algorithms Used for Translating Aptamer-Antigen Binding Kinetic Profiles to Diagnostic Decisions., PMID:39869304
Effect of Fusion to the LTB Carrier Protein on Coronavirus Spike Protein Vaccine Candidates Produced in Maize., PMID:39861796
The Long-Term Immunity of a Microneedle Array Patch of a SARS-CoV-2 S1 Protein Subunit Vaccine Irradiated by Gamma Rays in Mice., PMID:39852865
Broad-spectrum affinity chromatography of SARS-CoV-2 and Omicron vaccines from ligand screening to purification., PMID:39842145
Serological insights from SARS-CoV-2 heterologous prime and boost responses in Thailand., PMID:39789037
Affinity maturation endows potent activity onto class 6 SARS-CoV-2 broadly neutralizing antibodies., PMID:39746041
Evolution of SARS-CoV-2 spike trimers towards optimized heparan sulfate cross-linking and inter-chain mobility., PMID:39741163
Trivalent recombinant protein vaccine induces cross-neutralization against XBB lineage and JN.1 subvariants: preclinical and phase 1 clinical trials., PMID:39738039
Structure and dynamics of the interaction of Delta and Omicron BA.1 SARS-CoV-2 variants with REGN10987 Fab reveal mechanism of antibody action., PMID:39719448
Prompt engineering-enabled LLM or MLLM and instigative bioinformatics pave the way to identify and characterize the significant SARS-CoV-2 antibody escape mutations., PMID:39657873
Development and application of an uncapped mRNA platform., PMID:39648715
A Large-Scale Serological Survey in Pets From October 2020 Through June 2021 in France Shows Significantly Higher Exposure to SARS-CoV-2 in Cats Compared to Dogs., PMID:39648678
Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV., PMID:39644492
A potential bimodal interplay between heme and complement factor H 402H in the deregulation of the complement alternative pathway by SARS-CoV-2., PMID:39643072
Brussonol and komaroviquinone as inhibitors of the SARS-CoV-2 Omicron BA.2 variant spike protein: A molecular docking, molecular dynamics, and quantum biochemistry approach., PMID:39637552
For research use only. Not for human or drug use.
