Recombinant Human Dermokine beta/DMKN Protein, N-His

Catalog No.

YHK10502

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Gly22-Trp476

Predicted molecular weight

47.26 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>70% as determined by SDS-PAGE.

Accession

Q6E0U4

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Epidermis-specific secreted protein SK30/SK89, Dermokine, DMKN

Overexpression of Dermokine-α enhances the proliferation and epithelial-mesenchymal transition of pancreatic tumor cells., PMID:35981655

Functional and proteomic analysis of a full thickness filaggrin-deficient skin organoid model., PMID:31641698

Application of Monoclonal Antibodies Against Mouse Dermokine., PMID:28186437

Mice deficient for the epidermal dermokine β and γ isoforms display transient cornification defects., PMID:24794495

Dermokine inhibits ELR(+)CXC chemokine expression and delays early skin wound healing., PMID:23428944

Dermokine-β impairs ERK signaling through direct binding to GRP78., PMID:22735594

Altered expression of dermokine in skin disorders., PMID:22646803

The ubiquitous dermokine delta activates Rab5 function in the early endocytic pathway., PMID:21423773

Dermokine as a novel biomarker for early-stage colorectal cancer., PMID:20652332

Dermokine: an extensively differentially spliced gene expressed in epithelial cells., PMID:17380110

Identification of novel keratinocyte-secreted peptides dermokine-alpha/-beta and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1., PMID:15234001

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