Catalog No.
YHK05601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr269-Ser357
Predicted molecular weight
37.22 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8NFJ5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
G-protein coupled receptor family C group 5 member A, Phorbol ester induced gene 1, RAIG1, RAIG-1, PEIG-1, GPCR5A, GPRC5A, RAI3, Retinoic acid-induced gene 1 protein, Retinoic acid-induced protein 3
Proteogenomic analysis of the CALGB 40601 (Alliance) HER2+ breast cancer neoadjuvant trial reveals resistance biomarkers., PMID:40480221
Vitamin D and Retinoic Acid Require Protein Kinase C Activity and Reactive Oxygen Species as Opposing Signals Regulating PEIG-1/GPRC5A Expression in Caco-2 and T84 Colon Carcinoma Cells., PMID:40427604
Drug Resistance Analysis of Pancreatic Cancer Based on Universally Differentially Expressed Genes., PMID:40362181
NF-κB-mediated EAAT3 upregulation in antioxidant defense and ferroptosis sensitivity in lung cancer., PMID:39987248
Immunogenic dying cells elicit potent anti-tumor T cell immunity against lung metastasis and tumorigenesis., PMID:39825073
A noncanonical-GPRC5A signaling regulates keratinocyte adhesion and migration by nuclear translocation., PMID:39812615
GPRC5A promotes lung colonization of esophageal squamous cell carcinoma., PMID:39550386
Key genes and pathways in the molecular landscape of pancreatic ductal adenocarcinoma: A bioinformatics and machine learning study., PMID:39467488
Multiomics profiling of mouse polycystic kidney disease progression at a single-cell resolution., PMID:39405347
NF-κB represses retinoic acid receptor-mediated GPRC5A transactivation in lung epithelial cells to promote neoplasia., PMID:39377225
Transcriptome Analysis Reveals Novel Inflammatory Signalings to Glaesserella parasuis Infection., PMID:39202454
Expression of signal recognition particle 14 in hepatocellular carcinoma and its relationship with disease progression and patient survival., PMID:39183055
GPRC5A promotes gallbladder cancer metastasis by upregulating TNS4 via the JAK2-STAT3 pathway., PMID:38942137
GPRC5A is a potential prognostic biomarker and correlates with immune cell infiltration in non-small cell lung cancer., PMID:38854942
Gprc5a is a novel parathyroid hormone-inducible gene and negatively regulates osteoblast proliferation and differentiation., PMID:38769895
Availability of Receptors for Advanced Glycation End-Products (RAGE) Influences Differential Transcriptome Expression in Lungs from Mice Exposed to Chronic Secondhand Smoke (SHS)., PMID:38732159
Circular RNA hsa_circ_0094976 modulates GPR155 to inhibit gastric adenocarcinoma malignant characteristics by targeting miR-223-3p., PMID:38678850
GPRC5A promotes paclitaxel resistance and glucose content in NSCLC., PMID:38602327
[Inhibitory effect of downregulating G protein-coupled receptor class C group 5 member A expression on lipopolysaccharide-induced inflammatory response in human gingival fibroblasts]., PMID:38548591
Cross-sectional and longitudinal analyses of urinary extracellular vesicle mRNA markers in urothelial bladder cancer patients., PMID:38514751
Deciphering the molecular regulatory of RAB32/GPRC5A axis in chronic obstructive pulmonary disease., PMID:38448858
Influence of GPRC5A-Regulated ABCB1 Expression on Lung Adenocarcinoma Proliferation., PMID:38426412
Circ_0007351 Exerts an Oncogenic Role In Colorectal Cancer Depending on the Modulation of the miR-5195-3p/GPRC5A Cascade., PMID:38386274
Methylation of GPRC5A promotes liver metastasis and docetaxel resistance through activating mTOR signaling pathway in triple negative breast cancer., PMID:38335844
CircGPRC5A enhances colorectal cancer progress by stabilizing PPP1CA and inducing YAP dephosphorylation., PMID:38057879
Laminin 332 expression levels predict clinical outcomes and chemotherapy response in patients with pancreatic adenocarcinoma., PMID:37779898
GPRC5A regulates proliferation and oxidative stress by inhibiting the STAT3/Socs3/c-MYC pathway in hepatocellular carcinoma., PMID:37534091
The G protein-coupled receptor GPRC5A-a phorbol ester and retinoic acid-induced orphan receptor with roles in cancer, inflammation, and immunity., PMID:37467514
m6A Regulates the Stability of Cellular Transcripts Required for Efficient KSHV Lytic Replication., PMID:37376680
Chemoproteomics reveals microbiota-derived aromatic monoamine agonists for GPRC5A., PMID:37248411
RNA-binding protein ENO1 promotes the tumor progression of gastric cancer by binding to and regulating gastric cancer-related genes., PMID:37201055
TMT-based quantitative proteomic analysis of spheroid cells of endometrial cancer possessing cancer stem cell properties., PMID:37143105
Spatially multicellular variability of intervertebral disc degeneration by comparative single-cell analysis., PMID:37025067
RAI3 expression is not associated with clinical outcomes of patients with non-small cell lung cancer., PMID:36781501
Upregulated GPRC5A disrupting the Hippo pathway promotes the proliferation and migration of pancreatic cancer cells via the cAMP-CREB axis., PMID:36735162
Integrative analysis of the proteome and transcriptome in gastric cancer identified LRP1B as a potential biomarker., PMID:36606427
Massively parallel reporter assays and variant scoring identified functional variants and target genes for melanoma loci and highlighted cell-type specificity., PMID:36423637
NF-κB represses retinoic acid receptor-mediated GPRC5A transactivation in lung epithelial cells to promote neoplasia., PMID:36413416
Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis., PMID:36310237
Newly Released Advances in the Molecular Mechanisms of Osseous Metastasis and Potential Therapeutic Strategies., PMID:36246026
Pathogenesis of Tobacco-Associated Lung Adenocarcinoma Is Closely Coupled with Changes in the Gut and Lung Microbiomes., PMID:36142843
Practical identifiability analysis of a mechanistic model for the time to distant metastatic relapse and its application to renal cell carcinoma., PMID:36007057
Lung Cancer Cell of Origin: Controversy and Clinical Translational Implications., PMID:35288734
DNA methyltransferase 1 inhibits microRNA-497 and elevates GPRC5A expression to promote chemotherapy resistance and metastasis in breast cancer., PMID:35255904
A DNA-Methylation-Driven Genes Based Prognostic Signature Reveals Immune Microenvironment in Pancreatic Cancer., PMID:35222383
Development of human alveolar epithelial cell models to study distal lung biology and disease., PMID:35169685
Identification of Active Bronchioalveolar Stem Cells as the Cell of Origin in Lung Adenocarcinoma., PMID:35045987
Identification of Specific Cell Subpopulations and Marker Genes in Ovarian Cancer Using Single-Cell RNA Sequencing., PMID:34660776
Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis., PMID:34553078
Knockdown of GPRC5A inhibits cell proliferation, migration and invasion in osteosarcoma., PMID:34350749
For research use only. Not for human or drug use.
