Catalog No.
YHK05501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asp106
Predicted molecular weight
39.09 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UII2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IF1, Inhibitor of F(1)F(o)-ATPase, ATP synthase F1 subunit epsilon, IF(1), ATP5IF1, ATPI, ATPIF1, ATPase inhibitor, mitochondrial
Mitochondrial membrane hyperpolarization modulates nuclear DNA methylation and gene expression through phospholipid remodeling., PMID:40301431
Acute myeloid leukemia mitochondria hydrolyze ATP to support oxidative metabolism and resist chemotherapy., PMID:40203117
IF1 is a cold-regulated switch of ATP synthase hydrolytic activity to support thermogenesis in brown fat., PMID:39284909
Proteomic analyses on chicken breast meat with white striping myopathy., PMID:38593545
Alterations in Mitochondrial Oxidative Phosphorylation System: Relationship of Complex V and Cardiac Dysfunction in Human Heart Failure., PMID:38539818
Dysregulated immune and metabolic pathways are associated with poor survival in adult acute myeloid leukemia with CEBPA bZIP in-frame mutations., PMID:38253683
Dysregulation of MTFR2, ATP5IF1 and BAK1 in Sertoli cells relates to idiopathic non-obstructive azoospermia via inhibiting mitochondrial fission and inducing mitochondrial dysfunction†., PMID:37903059
IF1 ablation prevents ATP synthase oligomerization, enhances mitochondrial ATP turnover and promotes an adenosine-mediated pro-inflammatory phenotype., PMID:37433784
Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584., PMID:36993977
ATPIF1 alleviates oxygen glucose deprivation/reoxygenation-induced astrocyte injury in vitro: A rat model of ischemic brain injury., PMID:36881363
Towards the discovery of goat meat quality biomarkers using label-free proteomics., PMID:36871648
The mitochondrial inhibitor IF1 binds to the ATP synthase OSCP subunit and protects cancer cells from apoptosis., PMID:36690622
TNK2/ACK1-mediated phosphorylation of ATP5F1A (ATP synthase F1 subunit alpha) selectively augments survival of prostate cancer while engendering mitochondrial vulnerability., PMID:35895804
ATPase inhibitory factor 1 protects the heart from acute myocardial ischemia/reperfusion injury through activating AMPK signaling pathway., PMID:35002521
Development of an Oxidative Phosphorylation-Related and Immune Microenvironment Prognostic Signature in Uterine Corpus Endometrial Carcinoma., PMID:34901000
IF1 inactivation attenuates experimental colitis through downregulation of neutrophil infiltration in colon mucosa., PMID:34298397
Proteomic analysis of human frontal and temporal cortex using iTRAQ-based 2D LC-MS/MS., PMID:33952343
For research use only. Not for human or drug use.
