Catalog No.
YHK05201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr602-Ser772
Predicted molecular weight
21.27 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q92523
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CPT1B, Carnitine palmitoyltransferase 1B, CPT1-M, Carnitine O-palmitoyltransferase I, muscle isoform, CPT I, Carnitine O-palmitoyltransferase 1, muscle isoform, CPTI-M, Carnitine palmitoyltransferase I-like protein, KIAA1670
Expression of Carnitine Palmitoyltransferase I Isotypes in Gingival Tissues of Human Periodontitis., PMID:40499287
The effect of arsenic on mitochondrial fatty acid metabolism via inhibition of carnitine palmitoyltransferase 1B and choline kinase beta in C2C12 cells., PMID:40440347
Oral Sulforaphane Intervention Protects Against Diabetic Cardiomyopathy in db/db Mice: Focus on Cardiac Lipotoxicity and Substrate Metabolism., PMID:40427484
Lipid exposure leads to metabolic dysfunction in fetal sheep cardiomyocytes., PMID:40420618
The role of quercetin in modulating lipid metabolism and enhancing chemotherapy via the STAT3-CPT1B pathway in pancreatic cancer., PMID:40412371
Glucose, glutamine, lactic acid and α‑ketoglutarate restore metabolic disturbances and atrophic changes in energy‑deprived muscle cells., PMID:40376969
Mechanisms of Inonotus obliquus (Fr.) Pilát polysaccharides in ameliorating lipid-induced skeletal muscle insulin resistance via PI3K/AKT and AMPK/ACC1/CPT1 signaling pathways., PMID:40348308
Loss of RET-ROS at complex I induces diastolic dysfunction in mice that is reversed by aerobic exercise., PMID:40327410
Effects of maternal blood beta-hydroxybutyrate on brown adipose tissue functions and thermogenic and metabolic health in neonatal calves., PMID:40222674
International Union of Basic and Clinical Pharmacology. CXIX. Fundamental insights and clinical relevance regarding the carnitine palmitoyltransferase family of enzymes., PMID:40106976
Circular RNA CHACR is involved in the pathogenesis of cardiac hypertrophy., PMID:40093901
PKN2 enhances the immunosuppressive activity of polymorphonuclear myeloid-derived suppressor cells in esophageal carcinoma by mediating fatty acid oxidation., PMID:40069590
Changes in Protein Metabolism and Early Development of Sarcopenia in Mice With Cholestatic Liver Disease., PMID:39971588
LIPG-mediated regulation of lipid deposition and proliferation in goat intramuscular preadipocytes involves the PPARα signaling pathway., PMID:39946436
Integrative analysis of genes provides insights into the molecular and immune characteristics of mitochondria-related genes in atherosclerosis., PMID:39914597
Bisphenol S Induces Lipid Metabolism Disorders in HepG2 and SK-Hep-1 Cells via Oxidative Stress., PMID:39853042
Olanzapine exposure disordered lipid metabolism, gut microbiota and behavior in zebrafish (Danio rerio)., PMID:39788356
Mitochondrial SIRT2-mediated CPT2 deacetylation prevents diabetic cardiomyopathy by impeding cardiac fatty acid oxidation., PMID:39781464
Beta-aminoisobutyric acid improves bovine oocyte maturation and subsequent embryonic development by promoting lipid catabolism., PMID:39708666
Carnitine palmitoyltransferase 1 facilitates fatty acid oxidation in a non-cell-autonomous manner., PMID:39671290
PACS2/CPT1A/DHODH signaling promotes cardiomyocyte ferroptosis in diabetic cardiomyopathy., PMID:39633391
Multi-omics insights into the pathogenesis of diabetic cardiomyopathy: epigenetic and metabolic profiles., PMID:39623870
HMGB1 Modulates Macrophage Metabolism and Polarization in Ulcerative Colitis by Inhibiting Cpt1a Expression., PMID:39614449
The Protective Role of miR-130b-3p Against Palmitate-Induced Lipotoxicity in Cardiomyocytes Through PPARγ Pathway., PMID:39596228
Cyclosorus terminans extract mitigates submandibular gland changes associated with high-fat diet consumption in male rats., PMID:39561524
Impact of aerobic exercise on brain metabolism: Insights from spatial metabolomic analysis., PMID:39549874
The ZNF263/CPT1B axis regulates fatty acid β-oxidation to affect cisplatin resistance in lung adenocarcinoma., PMID:39500874
Sex Differences in Response to Diet Enriched With Glutathione Precursors in the Aging Heart., PMID:39492659
Modulation of Carnitine Palmitoyl Transferase 1b Expression and Activity in Muscle Pathophysiology in Osteoarthritis and Osteoporosis., PMID:39456222
Overexpression of CPT1A disrupts the maintenance and regenerative function of muscle stem cells., PMID:39382025
Cpt1a Drives primed-to-naïve pluripotency transition through lipid remodeling., PMID:39349670
Dietary supplementation with succinic acid improves growth performance and flesh quality of adult Nile tilapia (Oreochromis niloticus) fed a high-carbohydrate diet., PMID:39309970
[Changes in the expression of genes related to intestinal fatty acid oxidation and carnitine metabolism in patients with ulcerative colitis]., PMID:39307717
Liver transcriptome and proteome are modulated by nutrient restriction in early lactation cows challenged with intramammary lipopolysaccharide., PMID:39303391
Zinc-alpha2-glycoprotein modulates blood pressure by regulating renal lipid metabolism reprogramming-mediated urinary Na+ excretion in hypertension., PMID:39253990
Deficient RPE mitochondrial energetics leads to subretinal fibrosis in age-related neovascular macular degeneration., PMID:39223298
High-Protein Mulberry Leaves Improve Glucose and Lipid Metabolism via Activation of the PI3K/Akt/PPARα/CPT-1 Pathway., PMID:39201413
Involvement of mitochondrial fatty acid β-oxidation in the antiviral innate immune response in head kidney macrophages of large yellow croaker (Larimichthys crocea)., PMID:39142373
CPT1A-IL-10-mediated macrophage metabolic and phenotypic alterations ameliorate acute lung injury., PMID:39090662
Systemic inhibition of mitochondrial fatty acid β-oxidation impedes zebrafish ventricle regeneration., PMID:39059593
Decreased skeletal muscle intramyocellular lipid droplet-mitochondrial contact contributes to myosteatosis in cancer cachexia., PMID:39010842
The YY1-CPT1C signaling axis modulates the proliferation and metabolism of pancreatic tumor cells under hypoxia., PMID:38996932
MicroRNA-21 modulates brown adipose tissue adipogenesis and thermogenesis in a mouse model of polycystic ovary syndrome., PMID:38987854
Nutriomic Effects of Precision Lipids on Murine Hepatic Triacylglycerol Alterations Induced by High-Fat Diets., PMID:38952113
Cryptotanshinone alleviates liver fibrosis via inhibiting STAT3/CPT1A-dependent fatty acid oxidation in hepatic stellate cells., PMID:38936533
MT1G induces lipid droplet accumulation through modulation of H3K14 trimethylation accelerating clear cell renal cell carcinoma progression., PMID:38906969
APC/C-regulated CPT1C promotes tumor progression by upregulating the energy supply and accelerating the G1/S transition., PMID:38783346
Augmenter of liver regeneration knockout aggravates tubular ferroptosis and macrophage activation by regulating carnitine palmitoyltransferase-1A-induced lipid metabolism in diabetic nephropathy., PMID:38767438
Sirt5 improves cardiomyocytes fatty acid metabolism and ameliorates cardiac lipotoxicity in diabetic cardiomyopathy via CPT2 de-succinylation., PMID:38718533
2-Methoxyestradiol ameliorates doxorubicin-induced cardiotoxicity by regulating the expression of GLUT4 and CPT-1B in female rats., PMID:38652282
For research use only. Not for human or drug use.
