Catalog No.
YHK03401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Thr323
Predicted molecular weight
38.51 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UQ16
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KIAA0820, Dynamin-3, Dynamin, testicular, DNM3, T-dynamin
Folic Acid Promotes Peripheral Nerve Injury Repair via Regulating DNM3-AKT Pathway Through Mediating Methionine Cycle Metabolism., PMID:40163256
Proteomic analysis of carotid artery plaques with and without vulnerable features on magnetic resonance angiography with vessel wall imaging: a pilot study., PMID:40034248
Molecular Profiling of Sinonasal Adenoid Cystic Carcinoma: Canonical and Noncanonical Gene Fusions and Mutation., PMID:39760648
Discovery of Novel TULP4/ACTN4/EWSR1/ACTB::MYB and ESRRG::DNM3 Fusions Expands Molecular Landscape of Adenoid Cystic Carcinoma Beyond Fusions Between MYB/MYBL1 and NFIB Genes., PMID:39235305
Low-concentration imiquimod treatment promotes enhanced skin barrier functions through epidermal melanization reaction regulation., PMID:38760990
Uncovering novel drug targets for bipolar disorder: a Mendelian randomization analysis of brain, cerebrospinal fluid, and plasma proteomes., PMID:38720515
Osteoporosis GWAS-implicated DNM3 locus contextually regulates osteoblastic and chondrogenic fate of mesenchymal stem/progenitor cells through oscillating miR-199a-5p levels., PMID:38686038
The Structural and Functional Integrity of Rod Photoreceptor Ribbon Synapses Depends on Redundant Actions of Dynamins 1 and 3., PMID:38641407
ELAVL2 loss promotes aggressive mesenchymal transition in glioblastoma., PMID:38548861
Differential transcript usage across mammalian oocytes at the germinal vesicle and metaphase II stages., PMID:37995439
A novel proteomic-based model for predicting colorectal cancer with Schistosoma japonicum co-infection by integrated bioinformatics analysis and machine learning., PMID:37904220
Targeting of insulin receptor endocytosis as a treatment to insulin resistance., PMID:37788593
Differential Efficacy of Small Molecules Dynasore and Mdivi-1 for the Treatment of Dry Eye Epitheliopathy or as a Countermeasure for Nitrogen Mustard Exposure of the Ocular Surface., PMID:37442618
Locus for severity implicates CNS resilience in progression of multiple sclerosis., PMID:37380766
Decoding the genetic relationship between Alzheimer's disease and type 2 diabetes: potential risk variants and future direction for North Africa., PMID:37342358
Dynamins in human diseases: differential requirement of dynamin activity in distinct tissues., PMID:37230036
Zebrafish dnm1a gene plays a role in the formation of axons and synapses in the nervous tissue., PMID:37031448
Integrated multi-omic analysis of low-grade ovarian serous carcinoma collected from short and long-term survivors., PMID:36528667
Knockdown of miR-214 Alleviates Renal Interstitial Fibrosis by Targeting the Regulation of the PTEN/PI3K/AKT Signalling Pathway., PMID:36285295
Renal Farnesoid X Receptor improves high fructose-induced salt-sensitive hypertension in mice by inhibiting DNM3 to promote nitro oxide production., PMID:35792095
Expression of DNM3 is associated with good outcome in colorectal cancer., PMID:35178475
Endocytosis-associated patterns in nerve regeneration after peripheral nerve injury., PMID:34760620
The role of dynamin in absorbing lipids into endodermal epithelial cells of yolk sac membranes during embryonic development in Japanese quail., PMID:34624771
The biology, function, and applications of exosomes in cancer., PMID:34589397
Dynamin 3 Inhibits the Proliferation of Non-small-Cell Lung Cancer Cells by Suppressing c-MET-GBR2-STAT3 Complex Formation., PMID:34490234
Dynamin deficiency causes insulin secretion failure and hyperglycemia., PMID:34362840
β-Catenin/LEF-1 transcription complex is responsible for the transcriptional activation of LINC01278., PMID:34273985
DNM3OS Facilitates Ovarian Cancer Progression by Regulating miR-193a-3p/MAP3K3 Axis., PMID:34027641
Quantitative Fluorescent in situ Hybridization Reveals Differential Transcription Profile Sharpening of Endocytic Proteins in Cochlear Hair Cells Upon Maturation., PMID:33716676
TBX15 rs98422, DNM3 rs1011731, RAD51B rs8017304, and rs2588809 Gene Polymorphisms and Associations With Pituitary Adenoma., PMID:33622874
Delineation of the 1q24.3 microdeletion syndrome provides further evidence for the potential role of non-coding RNAs in regulating the skeletal phenotype., PMID:33141070
Analysis of DNM3 and VAMP4 as genetic modifiers of LRRK2 Parkinson's disease., PMID:32873436
Knocking Down Long Noncoding RNAs Using Antisense Oligonucleotide Gapmers., PMID:32865781
Role of LRRK2 variant p.Gly2019Ser in patients with Parkinsonism., PMID:32719233
Cooperation between SS18-SSX1 and miR-214 in Synovial Sarcoma Development and Progression., PMID:32019274
Signatures of altered DNA methylation gene expression after central and peripheral nerve injury., PMID:31691285
siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway., PMID:31388312
SNCA but not DNM3 and GAK modifies age at onset of LRRK2-related Parkinson's disease in Chinese population., PMID:31041581
Histone deacetylase 6 negatively regulated microRNA-199a-5p induces the occurrence of preeclampsia by targeting VEGFA in vitro., PMID:30947018
Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activity., PMID:30538113
Construction of a recombinant eukaryotic expression vector containing DNM3 gene and its expression in colon cancer cells., PMID:30349300
No evidence for DNM3 as genetic modifier of age at onset in idiopathic Parkinson's disease., PMID:30340792
Transcriptomes of cochlear inner and outer hair cells from adult mice., PMID:30277483
No association of DNM3 with age of onset in Asian Parkinson's disease., PMID:30133089
A fine-mapping study of central obesity loci incorporating functional annotation and imputation., PMID:29967334
Experimental and integrative analyses identify an ETS1 network downstream of BCR-ABL in chronic myeloid leukemia (CML)., PMID:29733872
Osteopontin deficiency ameliorates Alport pathology by preventing tubular metabolic deficits., PMID:29563333
α-synuclein (SNCA) but not dynamin 3 (DNM3) influences age at onset of leucine-rich repeat kinase 2 (LRRK2) Parkinson's disease in Spain., PMID:29473656
Characterization of a novel role for the dynamin mechanoenzymes in the regulation of human sperm acrosomal exocytosis., PMID:29044420
Dynamin 3 suppresses growth and induces apoptosis of hepatocellular carcinoma cells by activating inducible nitric oxide synthase production., PMID:28599479
For research use only. Not for human or drug use.
