Catalog No.
YHK03301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1569-Trp1755
Predicted molecular weight
23.59 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6W2J9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BCoR, BCL-6 corepressor, BCOR, KIAA1575
Single-cell sequencing reveals shared clonal signatures in nonmalignant B and tumor cells in T-prolymphocytic leukemia., PMID:40453149
GLIO-Select: Machine Learning-Based Feature Selection and Weighting of Tissue and Serum Proteomic and Metabolomic Data Uncovers Sex Differences in Glioblastoma., PMID:40362575
Targeted disruption of PRC1.1 complex enhances bone remodeling., PMID:40341537
BCOR and ZC3H12A suppress a core stemness program in exhausted CD8+ T cells., PMID:40327039
The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cells., PMID:40326560
Exploring the binding free energy landscape of intrinsically disordered protein-protein interactions: insights into the AF9-BCOR complex implicated in leukemia., PMID:40308178
Utility of Protein Kinase C Beta II Immunohistochemistry in Differential Diagnosis of Ewing Sarcoma., PMID:40230184
BCOR-rearranged sarcomas: In silico insights into altered domains and BCOR interactions., PMID:40228447
BCOR loss promotes both retinoblastoma growth and susceptibility to IGF1R inhibition., PMID:40214614
Impact of BCOR/BCORL1 mutation on outcomes of allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia patients., PMID:40202539
Bcor loss promotes Richter transformation of chronic lymphocytic leukemia associated with Notch1 activation in mice., PMID:40113912
A MAZ::NCOA2 Subcutaneous Small Round Cell Sarcoma of Infancy With Diffuse S100/SOX10 Positivity: A Novel Entity., PMID:39985329
Sinonasal EWSR1::POU2AF3 sarcoma: a case report and literature review., PMID:39982522
Hao-Fountain syndrome protein USP7 controls neuronal differentiation via BCOR-ncPRC1.1., PMID:39919828
Development, optimization and application of a universal fluorescence multiplex PCR-based assay to detect BCOR genetic alterations in pediatric tumors., PMID:39871307
Exome sequencing identifies existing and novel variants in a South African cohort presenting with anterior segment dysgenesis., PMID:39870121
Neonatal Encephalopathy: Novel Phenotypes and Genotypes Identified by Genome Sequencing., PMID:39810752
Molecular Profiling of Sinonasal Adenoid Cystic Carcinoma: Canonical and Noncanonical Gene Fusions and Mutation., PMID:39760648
Comprehensive characterization of MCL-1 in patients with colorectal cancer: Expression, molecular profiles, and outcomes., PMID:39740007
Emerging round cell sarcomas in children., PMID:39576278
Whole genome profiling of rare pediatric thoracic tumors elucidates a YAP1::LEUTX fusion in an unclassified biphasic embryonal neoplasm., PMID:39566337
Recurrent GRHL fusions in a subset of sebaceoma: microscopic and molecular characterisation of eight cases., PMID:39564735
BCOR-ITD Rearranged Sarcoma in the Mandible of a 5-Year-Old Child: A Case Report Highlighting Diagnostic Distinction From Odontogenic Fibromyxoma., PMID:39533763
SARCP, a Clinical Next-Generation Sequencing Assay for the Detection of Gene Fusions in Sarcomas: A Description of the First 652 Cases., PMID:39521244
[Undifferentiated small round cell sarcomas of bone and soft tissue]., PMID:39510958
Solitary subependymal giant cell astrocytoma lacking TSC1/2 mutations and TTF-1 expression: A potential diagnostic pitfall., PMID:39492623
[Diagnosis and Risk Stratification of Acute Myeloid Leukemia, Myelodysplasia -Related]., PMID:39479818
Genetic analysis using next-generation sequencing and multiplex ligation probe amplification in Chinese aniridia patients., PMID:39449022
Dental abnormalities observed in the oculo-facio-cardio-dental (OFCD) syndrome present in two Czech families bearing novel de novo BCOR pathogenic variants., PMID:39438869
Radiculomegaly as a key clinical feature in oculo-facio-cardio-dental (OFCD) syndrome: a case report with a novel truncating variant in BCOR gene., PMID:39390895
Identifying Novel Genetic Markers in Pediatric Rhabdomyosarcoma., PMID:39368853
Genomic alterations in retinoblastoma tumors of Argentine patients., PMID:39356046
Aberrant positivity for BCOR immunohistochemistry in merkel cell carcinoma - a potential diagnostic pitfall., PMID:39334415
The BCOR -rearranged sarcoma involving the lung: Diagnosis with clinical outcome and literature review., PMID:39285667
Prognostic impact of DTA mutation and co-occurring mutations in patients with myelodysplastic syndrome., PMID:39278886
Calcium modulates the tethering of BCOR-PRC1.1 enzymatic core to KDM2B via liquid-liquid phase separation., PMID:39256555
Orbital Sarcoma with BCOR Genetic Alterations in the Pediatric Age Group., PMID:39245644
Blast phase of chronic myeloid leukemia presenting as early T-cell precursor acute lymphoblastic leukemia., PMID:39235991
Molecular substratification of endometrial carcinomas with no special molecular profile (NSMP) by using a limited NGS custom panel may facilitate effective patient selection for the PIK3CA-targeted therapy., PMID:39235514
Epigenetic regulation of noncanonical menin targets modulates menin inhibitor response in acute myeloid leukemia., PMID:39158067
Prognostic mutations identified by whole-exome sequencing and validation of the Molecular International Prognostic Scoring System in myelodysplastic syndromes after allogeneic haematopoietic stem cell transplantation., PMID:39138006
The clinical implications of BCOR mutations in a large cohort of acute myeloid leukemia patients: a 5-year single-center retrospective study., PMID:39126311
Influence of genetic co-mutation on chemotherapeutic outcome in NPM1-mutated and FLT3-ITD wild-type AML patients., PMID:39126219
The DNA methylome of pediatric brain tumors appears shaped by structural variation and predicts survival., PMID:39117669
The Combined Immunohistochemical Expression of GLI1 and BCOR in Synovial Sarcomas for the Identification of Three Risk Groups and Their Prognostic Outcomes: A Study of 52 Patients., PMID:39062853
Case report: Metastatic refractory undifferentiated small round-cell sarcoma successfully treated with surufatinib and camrelizumab., PMID:39055564
Synovial Sarcoma of the Kidney: Diagnostic Pitfalls in a Case with Myxoid Monophasic Differentiation and No Epithelial Biomarkers Expression., PMID:39000489
Undifferentiated Round Cell Sarcoma With CRTC1::SS18 Fusion: Expanding Clinicopathologic Features of a Rare Translocation Sarcoma With Prominent Desmoplastic Stroma., PMID:38972355
Diagnostic Value of Combined BCOR, Cyclin D1, and CD10 in Differentiating Endometrial Stromal Sarcoma From Other Uterine Spindle Cell Lesions., PMID:38961542
A novel frameshift variant in BCOR causes congenital nuclear cataract., PMID:38957147
For research use only. Not for human or drug use.
