Catalog No.
YHK02301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Phe363
Predicted molecular weight
42.66 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H2M3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BHMT2, S-methylmethionine--homocysteine S-methyltransferase BHMT2, Betaine--homocysteine S-methyltransferase 2, SMM-hcy methyltransferase
Integrating network pharmacology, quantitative transcriptomic analysis, and experimental validation revealed the mechanism of cordycepin in the treatment of obesity., PMID:40438591
Integrated ubiquitomics characterization of hepatocellular carcinomas., PMID:39348425
Congenital Heart Disease and Genetic Changes in Folate/Methionine Cycles., PMID:39062651
Betaine alleviates spermatogenic cells apoptosis of oligoasthenozoospermia rat model by up-regulating methyltransferases and affecting DNA methylation., PMID:38735196
Spic regulates one-carbon metabolism and histone methylation in ground-state pluripotency., PMID:37595034
A novel estrogen receptor 1: sphingomyelin phosphodiesterase acid-like 3B pathway mediates rituximab response in myositis patients., PMID:36478205
Identification and validation of novel biomarkers affecting bladder cancer immunotherapy via machine learning and its association with M2 macrophages., PMID:36439109
Association of Maternal Betaine-Homocysteine Methyltransferase (BHMT) and BHMT2 Genes Polymorphisms with Congenital Heart Disease in Offspring., PMID:35835902
The genetic factors contributing to the risk of cleft lip-cleft palate and their clinical utility., PMID:35426585
An investigation to identify tumor microenvironment-related genes of prognostic value in lung squamous cell carcinoma based on The Cancer Genome Atlas., PMID:35116510
The plasma peptides of breast versus ovarian cancer., PMID:31889940
Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated with plasma hyperhomocysteinemia., PMID:30753104
Evidence of interaction between genes in the folate/homocysteine metabolic pathway in controlling risk of non-syndromic oral cleft., PMID:29356306
A Three-Way Interaction among Maternal and Fetal Variants Contributing to Congenital Heart Defects., PMID:26612412
Evolutionary Analyses and Natural Selection of Betaine-Homocysteine S-Methyltransferase (BHMT) and BHMT2 Genes., PMID:26213999
Folate-mediated one-carbon metabolism genes and interactions with nutritional factors on colorectal cancer risk: Women's Health Initiative Observational Study., PMID:26108676
Genetic modifiers of folate, vitamin B-12, and homocysteine status in a cross-sectional study of the Canadian population., PMID:25948668
Genome-wide expression in visceral adipose tissue from obese prepubertal children., PMID:25856673
Obstructive heart defects associated with candidate genes, maternal obesity, and folic acid supplementation., PMID:25846410
Genetic variants associated with protein C levels., PMID:23387557
Double-headed sulfur-linked amino acids as first inhibitors for betaine-homocysteine S-methyltransferase 2., PMID:22775318
A splicing variant leads to complete loss of function of betaine-homocysteine methyltransferase (BHMT) gene in hepatocellular carcinoma., PMID:22138536
Transcobalamin 2 variant associated with poststroke homocysteine modifies recurrent stroke risk., PMID:21975197
Polymorphic variants of genes involved in homocysteine metabolism in celiac disease., PMID:21688148
Polymorphic variants of folate and choline metabolism genes and the risk of endometriosis-associated infertility., PMID:21429654
Folate pathway and nonsyndromic cleft lip and palate., PMID:21254359
Betaine-homocysteine methyltransferase: human liver genotype-phenotype correlation., PMID:21093336
Polymorphisms located in the region containing BHMT and BHMT2 genes as maternal protective factors for orofacial clefts., PMID:20662904
Yeast, plants, worms, and flies use a methyltransferase to metabolize age-damaged (R,S)-AdoMet, but what do mammals do?, PMID:20370499
Associations of folate and choline metabolism gene polymorphisms with orofacial clefts., PMID:19737740
Genetic analysis of 56 polymorphisms in 17 genes involved in methionine metabolism in patients with abdominal aortic aneurysm., PMID:18635682
Human betaine-homocysteine methyltransferase (BHMT) and BHMT2: common gene sequence variation and functional characterization., PMID:18457970
Alteration of gene expression in rat colon mucosa after exercise., PMID:18342145
Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase., PMID:18230605
Are the betaine-homocysteine methyltransferase (BHMT and BHMT2) genes risk factors for spina bifida and orofacial clefts?, PMID:15887275
Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease., PMID:12818402
Betaine-homocysteine methyltransferase-2: cDNA cloning, gene sequence, physical mapping, and expression of the human and mouse genes., PMID:11087663
For research use only. Not for human or drug use.
