Catalog No.
YHK01701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg123-Lys393
Predicted molecular weight
33.88 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BX97
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PLVAP, Plasmalemma vesicle protein 1, Plasmalemma vesicle-associated protein, Fenestrated endothelial-linked structure protein, PV-1, FELS, PV1
Dissecting the endothelial cell landscape in meningioma: single-cell insights into PLVAP+ subpopulations and their role in tumor angiogenesis., PMID:40496867
Several Common Genetic Variations Associate With Functional or Anatomic Effects of Anti-VEGF Treatment in Conditions With Macular Edema., PMID:40455044
Characterization of Extrachromosomal Circular DNA in Primary and Cisplatin-Resistant High-Grade Serous Ovarian Cancer., PMID:40428339
Identification of Hub Genes and Key Pathways Associated with Sepsis Progression Using Weighted Gene Co-Expression Network Analysis and Machine Learning., PMID:40362669
Spatial transcriptional landscape of human heart failure., PMID:40335066
ADAMTS18 deficiency leads to abnormal brain methylation metabolism, dysregulated neuroinflammatory response, and unsound blood-brain barrier structure in mice., PMID:40227359
Can we talk? The cryptic communications of hepatic stellate cells in lipid metabolism., PMID:40174572
Short-chain fatty acid attenuates intestinal inflammation by regulation of gut microbial composition in antibiotic-associated diarrhea., PMID:40092732
Hepatic stellate cells regulate liver fatty acid utilization via plasmalemma vesicle-associated protein., PMID:40037362
Transcriptional Responses of In Vitro Blood-Brain Barrier Models to Shear Stress., PMID:40001496
Blockade of P2X7 receptors preserves blood retinal barrier integrity by modulating the plasmalemma vesicle-associated protein: Implications for diabetic retinopathy., PMID:39978783
Transcriptome analysis of early- and late-onset Alzheimer's disease in Korean cohorts., PMID:39935412
Abnormal Vessels Potentially Accelerate Glioblastoma Proliferation by Inducing the Protumor Activation of Macrophages., PMID:39921277
Single-cell atlas of human pancreatic islet and acinar endothelial cells in health and diabetes., PMID:39915484
Construction of a radiogenomic signature based on endoplasmic reticulum stress for predicting prognosis and systemic combination therapy response in hepatocellular carcinoma., PMID:39849389
ENDOTHELIAL PROX1 INDUCES BLOOD-BRAIN BARRIER DISRUPTION IN THE CENTRAL NERVOUS SYSTEM., PMID:39803470
Induction of plasmalemmal vesicle-associated protein exacerbates glomerular endothelial injury in thrombotic microangiopathy., PMID:39706169
Exploring the Role of Gut Vascular Barrier Proteins in HIV-Induced Mucosal Damage: A Comparative Study., PMID:39501662
Single-Cell Meta-Analysis Uncovers the Pancreatic Endothelial Cell Transcriptomic Signature and Reveals a Key Role for NKX2-3 in PLVAP Expression., PMID:39445426
Molecular and Functional Alterations in the Cerebral Microvasculature in an Optimized Mouse Model of Sepsis-Associated Cognitive Dysfunction., PMID:39266325
Unraveling the molecular architecture of autoimmune thyroid diseases at spatial resolution., PMID:39003267
Macrophages preserve endothelial cell specialization in the adrenal gland to modulate aldosterone secretion and blood pressure., PMID:38941187
A sophisticated virulence repertoire and colistin resistance of Citrobacter freundii ST150 from a patient with sepsis admitted to ICU in a tertiary care hospital in Uganda, East Africa: Insight from genomic and molecular docking analyses., PMID:38604286
Angiotensin-converting enzyme inhibitors provide a protective effect on hypoxia-induced injury in human coronary artery endothelial cells via Nrf2 signaling and PLVAP., PMID:38339922
From Homogeneity to Turing Pattern: Kinetically Controlled Self-Organization of Transmembrane Protein., PMID:38198287
Presence of onco-fetal neighborhoods in hepatocellular carcinoma is associated with relapse and response to immunotherapy., PMID:38168935
Induction of Fenestrae in Human Induced Pluripotent Stem Cell-Derived Endothelial Cells for Disease Modeling., PMID:38126303
Differential roles of eNOS in late effects of VEGF-A on hyperpermeability in different types of endothelial cells., PMID:38052807
Pharmacological Modulation of β-Catenin Preserves Endothelial Barrier Integrity and Mitigates Retinal Vascular Permeability and Inflammation., PMID:38002758
The senescent secretome drives PLVAP expression in cultured human hepatic endothelial cells to promote monocyte transmigration., PMID:37810232
Expression analysis of plvap in mouse heart development, homeostasis and injury., PMID:37774966
Multi-ancestry GWAS analysis identifies two novel loci associated with diabetic eye disease and highlights APOL1 as a high risk locus in patients with diabetic macular edema., PMID:37585454
Caveolae-mediated endocytosis pathway regulates endothelial fenestra homeostasis in the rat pituitary., PMID:37506534
Downregulation of VEGF in the retinal pigment epithelium followed by choriocapillaris atrophy after NaIO3 treatment in mice., PMID:37479076
Comparative Transcriptomic Analysis of Archival Human Vestibular Schwannoma Tissue from Patients with and without Tinnitus., PMID:37048724
Structural insights into plasmalemma vesicle-associated protein (PLVAP): Implications for vascular endothelial diaphragms and fenestrae., PMID:36996108
Single-cell sequencing reveals that endothelial cells, EndMT cells and mural cells contribute to the pathogenesis of cavernous malformations., PMID:36914857
PLVAP protein expression correlated with microbial composition, clinicopathological features, and prognosis of patients with stomach adenocarcinoma., PMID:36884119
The role of PLVAP in endothelial cells., PMID:36781482
Netrin-1 binding to Unc5B regulates Blood-Retina Barrier integrity., PMID:36711611
PLVAP as an Early Marker of Glomerular Endothelial Damage in Mice with Diabetic Kidney Disease., PMID:36674624
Wnt signaling regulates MFSD2A-dependent drug delivery through endothelial transcytosis in glioma., PMID:36591963
Brain endothelial cells acquire blood-brain barrier properties in the absence of Vegf-dependent CNS angiogenesis., PMID:36502932
Gold nanoparticle delivery to solid tumors: a multiparametric study on particle size and the tumor microenvironment., PMID:36494816
CEP192 is a novel prognostic marker and correlates with the immune microenvironment in hepatocellular carcinoma., PMID:36238304
Regulation of fenestra formation via actin-dynamin2 interaction in rat pituitary endothelial cells., PMID:36102975
PLVAP is associated with glioma-associated malignant processes and immunosuppressive cell infiltration as a promising marker for prognosis., PMID:36033326
Generation of Plvap-CreER and Car4-CreER for genetic targeting of distinct lung capillary populations., PMID:36028133
Analysis of Non-Relapsed and Relapsed Adult Type Granulosa Cell Tumors Suggests Stable Transcriptomes during Tumor Progression., PMID:35723333
Stimulatory G-Protein α Subunit Modulates Endothelial Cell Permeability Through Regulation of Plasmalemma Vesicle-Associated Protein., PMID:35721211
For research use only. Not for human or drug use.
