Catalog No.
YHK01001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val59-Thr301
Predicted molecular weight
29.34 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H172
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATP-binding cassette sub-family G member 4, ABCG4, WHITE2
A symbiotic bacterium regulates the detoxification metabolism of deltamethrin in Aedes albopictus., PMID:40500053
A Structural Bioinformatics-Guided Study of Adenosine Triphosphate-Binding Cassette (ABC) Transporters and Their Substrates., PMID:39852261
The ATP-binding cassette transporter subfamily G member 4 mediates cuticular hydrocarbon transport to regulate drought tolerance in Acyrthosiphon pisum., PMID:39127281
Behavioral and Metabolic Effects of ABCG4 KO in the APPswe,Ind (J9) Mouse Model of Alzheimer's Disease., PMID:38668787
Proteomic study of left ventricle and cortex in rats after myocardial infarction., PMID:38514755
Tumor-associated macrophage (TAM)-secreted CCL22 confers cisplatin resistance of esophageal squamous cell carcinoma (ESCC) cells via regulating the activity of diacylglycerol kinase α (DGKα)/NOX4 axis., PMID:38387281
Effect of Naoxintong Capsule on Microglia and Proteomics of Cortex After Myocardial Infarction in Rats., PMID:37948003
The Reentry Helix Is Potentially Involved in Cholesterol Sensing of the ABCG1 Transporter Protein., PMID:36430223
Functional analysis of cyantraniliprole tolerance ability mediated by ATP-binding cassette transporters in Aphis gossypii glover., PMID:35715043
Multi-omics analysis identifies a CYP9K1 haplotype conferring pyrethroid resistance in the malaria vector Anopheles funestus in East Africa., PMID:35546741
Knockout of ABC Transporter ABCG4 Gene Confers Resistance to Cry1 Proteins in Ostrinia furnacalis., PMID:35051029
Identification and Functional Analysis of Differentially Expressed Genes in Myzus persicae (Hemiptera: Aphididae) in Response to Trans-anethole., PMID:34958664
ABCG1 and ABCG4 as key transporters in the development of pulmonary alveolar proteinosis by nanoparticles., PMID:34256330
Mammalian ABCG-transporters, sterols and lipids: To bind perchance to transport?, PMID:33309976
The Interplay of ABC Transporters in Aβ Translocation and Cholesterol Metabolism: Implicating Their Roles in Alzheimer's Disease., PMID:33215389
Regulation of ABCG4 transporter expression by sterols and LXR ligands., PMID:33141061
ABC Transporters, Cholesterol Efflux, and Implications for Cardiovascular Diseases., PMID:32705595
The miR-9b microRNA mediates dimorphism and development of wing in aphids., PMID:32217736
MiR-202-3p Inhibits Foam Cell Formation and is Associated with Coronary Heart Disease Risk in a Chinese Population., PMID:31956131
Gene silencing through RNAi and antisense Vivo-Morpholino increases the efficacy of pyrethroids on larvae of Anopheles stephensi., PMID:31462239
The Adaptor Protein Alix is Involved in the Interaction Between the Ubiquitin Ligase NEDD4-1 and its Targets, ABCG1 and ABCG4., PMID:31159502
ABC Transporters in Neurological Disorders: An Important Gateway for Botanical Compounds Mediated Neuro-Therapeutics., PMID:30977450
Effects of exercise on reverse cholesterol transport: A systemized narrative review of animal studies., PMID:30922848
Doxorubicin induces prostate cancer drug resistance by upregulation of ABCG4 through GSH depletion and CREB activation: Relevance of statins in chemosensitization., PMID:30834613
Gestational age-dependent gene expression profiling of ATP-binding cassette transporters in the healthy human placenta., PMID:30407748
ApoE isoforms and carboxyl-terminal-truncated apoE4 forms affect neuronal BACE1 levels and Aβ production independently of their cholesterol efflux capacity., PMID:29743204
Inhibition of miR-486 and miR-92a decreases liver and plasma cholesterol levels by modulating lipid-related genes in hyperlipidemic hamsters., PMID:29725814
Oxidative Stress in HIV Infection and Alcohol Use: Role of Redox Signals in Modulation of Lipid Rafts and ATP-Binding Cassette Transporters., PMID:29132227
Expression and function of Abcg4 in the mouse blood-brain barrier: role in restricting the brain entry of amyloid-β peptide., PMID:29042617
Genome-Wide QTL Analysis Identified Significant Associations Between Hypoxia Tolerance and Mutations in the GPR132 and ABCG4 Genes in Nile Tilapia., PMID:28698960
ABC Transport Proteins in Cardiovascular Disease-A Brief Summary., PMID:28383515
Implications of cerebrovascular ATP-binding cassette transporter G1 (ABCG1) and apolipoprotein M in cholesterol transport at the blood-brain barrier., PMID:28315462
ABC-Transporter Mediated Sterol Export from Cells Using Radiolabeled Sterols., PMID:28205181
Modulation of miR-185-5p expression by EBV-miR-BART6 contributes to developmental differences in ABCG4 gene expression in human megakaryocytes., PMID:27816548
MicroRNA-463-3p/ABCG4: A new axis in glucose-stimulated insulin secretion., PMID:27664094
Proteomics-based identification of midgut proteins correlated with Cry1Ac resistance in Plutella xylostella (L.)., PMID:27521921
Functional Cooperativity between ABCG4 and ABCG1 Isoforms., PMID:27228027
ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production., PMID:27196068
Age-Dependent Regulation of the Blood-Brain Barrier Influx/Efflux Equilibrium of Amyloid-β Peptide in a Mouse Model of Alzheimer's Disease (3xTg-AD)., PMID:26484906
Frequent down-regulation of ABC transporter genes in prostate cancer., PMID:26459268
Immunohistochemical analysis of transporters related to clearance of amyloid-β peptides through blood-cerebrospinal fluid barrier in human brain., PMID:26449856
Mitochondrial regulation of macrophage cholesterol homeostasis., PMID:26416507
The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters., PMID:26296893
High ABCG4 Expression Is Associated with Poor Prognosis in Non-Small-Cell Lung Cancer Patients Treated with Cisplatin-Based Chemotherapy., PMID:26270652
The impairment of cholesterol metabolism in Huntington disease., PMID:25596342
ABCA1, ABCG1, and ABCG4 are distributed to distinct membrane meso-domains and disturb detergent-resistant domains on the plasma membrane., PMID:25302608
Targeting mitochondrial 18 kDa translocator protein (TSPO) regulates macrophage cholesterol efflux and lipid phenotype., PMID:24814875
Docosahexaenoic acid modulates the enterocyte Caco-2 cell expression of microRNAs involved in lipid metabolism., PMID:24623846
ATP-binding cassette transporters, atherosclerosis, and inflammation., PMID:24385509
Effects of a fixed-intensity of endurance training and pistacia atlantica supplementation on ATP-binding cassette G4 expression., PMID:24267473
For research use only. Not for human or drug use.
