Catalog No.
YHK00801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Pro157
Predicted molecular weight
20.13 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y6W3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PalBH, PalB homolog, CAPN7, PALBH, Calpain-7
The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission., PMID:37772788
Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission., PMID:36107470
Calpain7 negatively regulates human endometrial stromal cell decidualization in EMs by promoting FoxO1 nuclear exclusion via hydrolyzing AKT1., PMID:35191464
[Mir-29c-3p targeting TUG1 affects migration and invasion of bladder cancer cells by regulating CAPN7 expression]., PMID:32990242
Structures and functions of penta-EF-hand calcium-binding proteins and their interacting partners: enigmatic relationships between ALG-2 and calpain-7., PMID:31814542
Drug screening with human SMN2 reporter identifies SMN protein stabilizers to correct SMA pathology., PMID:30910806
In Vivo Monitoring of Calpain Activity by Forster Resonance Energy Transfer., PMID:30617795
LINC00657 promotes the development of colon cancer by activating PI3K/AKT pathway., PMID:30338799
Identification of biomarker candidates for fertility in spermatozoa of crossbred bulls through comparative proteomics., PMID:29982135
Calpain7 impairs embryo implantation by downregulating β3-integrin expression via degradation of HOXA10., PMID:29459744
Liaison alcaline: Pals entice non-endosomal ESCRTs to the plasma membrane for pH signaling., PMID:25460796
Involvement of calpain-7 in epidermal growth factor receptor degradation via the endosomal sorting pathway., PMID:24953135
CAPN 7 promotes the migration and invasion of human endometrial stromal cell by regulating matrix metalloproteinase 2 activity., PMID:23855590
Analysis of limited proteolytic activity of calpain-7 using non-physiological substrates in mammalian cells., PMID:23497113
Androglobin: a chimeric globin in metazoans that is preferentially expressed in Mammalian testes., PMID:22115833
Calpain-7 binds to CHMP1B at its second α-helical region and forms a ternary complex with IST1., PMID:21616915
Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT-MIM interaction., PMID:20849418
Human calpain 7/PalBH associates with a subset of ESCRT-III-related proteins in its N-terminal region and partly localizes to endocytic membrane compartments., PMID:18316332
Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus., PMID:14981075
Capn7: a highly divergent vertebrate calpain with a novel C-terminal domain., PMID:10051333
For research use only. Not for human or drug use.
