Catalog No.
YHK00401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu26-Arg495
Predicted molecular weight
57.27 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y6Q1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Calpamodulin, Calpain-6, CALPM, CANPX, Calpain-like protease X-linked, CAPN6, CalpM
Gene expression profiling and the isocitrate dehydrogenase mutational landscape of temozolomide‑resistant glioblastoma., PMID:38939621
Advanced glycation end products promote the progression of chronic kidney diseases by targeting calpain 6., PMID:37243758
HuR Promotes the Differentiation of Goat Skeletal Muscle Satellite Cells by Regulating Myomaker mRNA Stability., PMID:37108057
The specific phagocytosis regulators could predict recurrence and therapeutic effect in thyroid cancer: A study based on bioinformatics analysis., PMID:36930113
H3K4me3 mediates uterine leiomyoma pathogenesis via neuronal processes, synapsis components, proliferation, and Wnt/β-catenin and TGF-β pathways., PMID:36703136
A calpain-6/YAP axis in sarcoma stem cells that drives the outgrowth of tumors and metastases., PMID:36153320
Calpain 6 inhibits autophagy in inflammatory environments: A preliminary study on myoblasts and a chronic kidney disease rat model., PMID:34435644
CAPN6 in disease: An emerging therapeutic target (Review)., PMID:33000175
CAPN6 Regulates Uterine Leiomyoma Cell Proliferation and Apoptosis through the Rac1-Dependent Signaling Pathway., PMID:32161009
Non-proteolytic calpain-6 interacts with VEGFA and promotes angiogenesis by increasing VEGF secretion., PMID:31673071
Functional study of 14-3-3 protein epsilon (YWHAE) in keratinocytes: microarray integrating bioinformatics approaches., PMID:31244373
Calpain-6 controls the fate of sarcoma stem cells by promoting autophagy and preventing senescence., PMID:30185659
Integrated analysis reveals candidate mRNA and their potential roles in uterine leiomyomas., PMID:27987347
Calpain-6 confers atherogenicity to macrophages by dysregulating pre-mRNA splicing., PMID:27525442
miR-449a promotes liver cancer cell apoptosis by downregulation of Calpain 6 and POU2F1., PMID:26375440
Transcriptome analysis of the human corneal endothelium., PMID:25377225
A marker-derived gene network reveals the regulatory role of PPARGC1A, HNF4G, and FOXP3 in intramuscular fat deposition of beef cattle., PMID:24778332
Calpain-6 deficiency promotes skeletal muscle development and regeneration., PMID:23935533
Gene and protein patterns of potential prion-related markers in the central nervous system of clinical and preclinical infected sheep., PMID:23497022
Transcriptional sexual dimorphism in elongating bovine embryos: implications for XCI and sex determination genes., PMID:21411694
Calpain-6, a microtubule-stabilizing protein, regulates Rac1 activity and cell motility through interaction with GEF-H1., PMID:21406564
The PI3K-Akt pathway regulates calpain 6 expression, proliferation, and apoptosis., PMID:21255642
Calpain-6, a target molecule of glucocorticoids, regulates osteoclastic bone resorption via cytoskeletal organization and microtubule acetylation., PMID:20814968
Genome-wide mapping of quantitative trait loci for fatness, fat cell characteristics and fat metabolism in three porcine F2 crosses., PMID:20667088
Cluster analysis and phylogenetic relationship in biomarker identification of type 2 diabetes and nephropathy., PMID:20431808
Sex determines the expression level of one third of the actively expressed genes in bovine blastocysts., PMID:20133684
Increased expression of calpain 6 during the progression of uterine cervical neoplasia: immunohistochemical analysis., PMID:18357368
Increased expression of calpain 6 in uterine sarcomas and carcinosarcomas: an immunohistochemical analysis., PMID:17291261
Calpain 6 is involved in microtubule stabilization and cytoskeletal organization., PMID:17210638
The calpain inhibitor VI prevents apoptosis of adult motor neurons., PMID:15973149
Diverse mRNA expression patterns of the mouse calpain genes Capn5, Capn6 and Capn11 during development., PMID:10559499
A new subfamily of vertebrate calpains lacking a calmodulin-like domain: implications for calpain regulation and evolution., PMID:9339374
For research use only. Not for human or drug use.
