Catalog No.
YHK00301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ala205
Predicted molecular weight
24.68 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BPU6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Collapsin response mediator protein 5, CRAM, CRMP-5, Dihydropyrimidinase-related protein 5, ULIP-6, UNC33-like phosphoprotein 6, CRMP5, ULIP6, DPYSL5, DRP-5, CRMP3-associated molecule
Immune genes involved in synaptic plasticity during early postnatal brain development contribute to post-stroke damage in the aging male rat brain., PMID:39966204
Late-onset Chorea with a Rare but Identifiable Cause., PMID:38881119
Anlotinib induces neuronal-like differentiation of neuroblastoma by downregulating CRMP5., PMID:38780126
Cortical laminar necrosis due to hypoglycemia in anti-CV2/CRMP5 paraneoplastic encephalitis: a curious association., PMID:38563874
DPYSL5 is highly expressed in treatment-induced neuroendocrine prostate cancer and promotes lineage plasticity via EZH2/PRC2., PMID:38238517
A novel proteomic-based model for predicting colorectal cancer with Schistosoma japonicum co-infection by integrated bioinformatics analysis and machine learning., PMID:37904220
Contribution of the dihydropyrimidinase-like proteins family in synaptic physiology and in neurodevelopmental disorders., PMID:37144098
Genetic variants for prediction of gestational diabetes mellitus and modulation of susceptibility by a nutritional intervention based on a Mediterranean diet., PMID:36313769
Expanding the pre- and postnatal phenotype of WASHC5 and CCDC22 -related Ritscher-Schinzel syndromes., PMID:36130690
Spastin interacts with CRMP5 to promote spindle organization in mouse oocytes by severing microtubules., PMID:34034836
Missense variants in DPYSL5 cause a neurodevelopmental disorder with corpus callosum agenesis and cerebellar abnormalities., PMID:33894126
Collapsin response mediator protein 5 (CRMP5) modulates susceptibility to chronic social defeat stress in mice., PMID:33638112
Small cell carcinoma presenting as ocular paraneoplastic syndrome due to CRMP-5., PMID:33459291
CRMP-5-IgG Antibody: role in the bilateral uveitis with swollen disc., PMID:32685790
[A case of paraneoplastic myelopathy associated with anti-CV2/CRMP5 antibodies with small-cell lung cancer]., PMID:32641628
A circRNA derived from linear HIPK3 relieves the neuronal cell apoptosis in spinal cord injury via ceRNA pattern., PMID:32247616
Anti-CV2/CRMP5 antibody-associated hemorrhagic leukoencephalomyelitis treated with steroids, intravenous immunoglobulin, plasmapheresis, and cyclophosphamide., PMID:32044694
Rare case: paraneoplastic syndrome affecting peripheral nerves, associated with anti-collapsin-response mediator protein-5 (anti-CRMP5) antibodies, as early manifestation of small cell lung cancer confined to a solitary lymph node without evidence of lung mass on routine CT thorax., PMID:32033998
Limbic encephalitis associated with AMPA receptor and CRMP5 antibodies: A case report and literature review., PMID:31991060
Collapsin Response-Mediator Protein 5-Associated Retinitis, Vitritis, and Optic Disc Edema., PMID:31676123
Anti-CV2/CRMP5 Paraneoplastic Chorea Effectively Managed with Intravenous Amantadine., PMID:31656691
Amphiphysin-IgG autoimmune neuropathy: A recognizable clinicopathologic syndrome., PMID:31624089
Pharmacological and proteomic analyses of neonatal polyI:C-treated adult mice., PMID:31446906
A Novel Intergenic Region between CENPA and DPYSL5-ALK Exon 20 Fusion Variant Responding to Crizotinib Treatment in a Patient with Lung Adenocarcinoma., PMID:31445731
miR-214-5p inhibits human prostate cancer proliferation and migration through regulating CRMP5., PMID:31403941
Collapsin response mediator protein 5 (CRMP5) causes social deficits and accelerates memory loss in an animal model of Alzheimer's disease., PMID:31233825
Detection of serum anti-retinal antibodies in the Chinese patients with presumed autoimmune retinopathy., PMID:31119427
Inflammatory flaccid myelitis in a patient with both anti-CRMP-5 IgG and CNS HIV escape., PMID:31118171
Anti-CV2-Associated Paraneoplastic Hemichorea Secondary to Diffuse Large B-cell Lymphoma., PMID:31057136
Genome-wide association analysis reveals KCTD12 and miR-383-binding genes in the background of rumination., PMID:30886212
CRMP5-associated GTPase (CRAG) Is a Candidate Driver Gene for Colorectal Cancer Carcinogenesis., PMID:30591445
Spastin Interacts with CRMP5 to Promote Neurite Outgrowth by Controlling the Microtubule Dynamics., PMID:30257070
Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression., PMID:30181555
Paraneoplastic striatal encephalitis and myelitis associated with anti-CV2/CRMP-5 antibodies in a patient with small cell lung cancer., PMID:29777943
Coexistence of Lambert-Eaton myasthenic syndrome and autoimmune encephalitis with anti-CRMP5/CV2 and anti-GABAB receptor antibodies in small cell lung cancer: A case report., PMID:29742721
Autoimmune encephalitis positive for both anti-γ-aminobutyric acid B receptor and anticollapsin response-mediator protein 5 antibodies: A case report., PMID:29504979
CV2/CRMP5-antibody-related Paraneoplastic Optic Neuropathy Associated with Small-cell Lung Cancer., PMID:29321433
Paraneoplastic Optic Neuropathy and Pineal Germinoma With Collapsin Response-Mediating Protein Antibodies., PMID:29266032
Autoimmune CRMP5 neuropathy phenotype and outcome defined from 105 cases., PMID:29222126
Movement disorders with neuronal antibodies: syndromic approach, genetic parallels and pathophysiology., PMID:29053777
Transcriptional regulation of CRMP5 controls neurite outgrowth through Sox5., PMID:28864883
Blocking CRMP2 SUMOylation reverses neuropathic pain., PMID:28533518
DRP5 is involved in cancer cell growth and predicts poor prognosis in human osteosarcoma., PMID:28374915
Differentially expressed proteins underlying childhood cortical dysplasia with epilepsy identified by iTRAQ proteomic profiling., PMID:28222113
Stable isotope metabolic labeling suggests differential turnover of the DPYSL protein family., PMID:27763719
Integration of zebrafish fin regeneration genes with expression data of human tumors in silico uncovers potential novel melanoma markers., PMID:27689402
Double trouble: para-neoplastic anti-PCA-2 and CRMP-5-mediated small fibre neuropathy followed by chorea associated with small cell lung cancer and evolving radiological features., PMID:27571910
Rapidly progressive neurological deterioration in anti-AMPA receptor encephalitis with additional CRMP5 antibodies., PMID:27465029
Anti-collapsin response mediator protein 5 encephalitis masquerading as a low-grade brain tumour., PMID:27247429
Autoimmune myelopathies., PMID:27112686