Catalog No.
YHJ98901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys249
Predicted molecular weight
30.92 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8IV48
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HEXO, Histone mRNA 3'-end-specific exoribonuclease, Protein 3'hExo, Eri-1 homolog, 3'-5' exonuclease ERI1, Histone mRNA 3'-exonuclease 1, 3'-5' exoribonuclease 1, THEX1, 3'EXO, ERI1
Genome-wide association study and multi-ancestry meta-analysis identify common variants associated with carotid artery intima-media thickness., PMID:40321265
Mendelian randomization provides a multi-omics perspective on the regulation of genes involved in ribosome biogenesis in relation to cardiac structure and function., PMID:40045424
Peri-centrosomal localization of small interfering RNAs in C. elegans., PMID:39825209
The ER-Resident Ras Inhibitor 1 (Eri1) of Candida albicans Inhibits Hyphal Morphogenesis via the Ras-Independent cAMP-PKA Pathway., PMID:39119676
Genomic selection pressure discovery using site-frequency spectrum and reduced local variability statistics in Pakistani Dera-Din-Panah goat., PMID:37750990
Investigation of potential prognostic biomarkers for colorectal cancer., PMID:40395892
Null and missense mutations of ERI1 cause a recessive phenotypic dichotomy in humans., PMID:37352860
Construction and Verification of an RNA-Binding Protein-Associated Prognostic Model for Gliomas., PMID:36867360
Manganese-dependent microRNA trimming by 3'→5' exonucleases generates 14-nucleotide or shorter tiny RNAs., PMID:36508664
ERI1: A case report of an autosomal recessive syndrome associated with developmental delay and distal limb abnormalities., PMID:36208065
Identification of a 6-RBP gene signature for a comprehensive analysis of glioma and ischemic stroke: Cognitive impairment and aging-related hypoxic stress., PMID:36118697
Association of Circulating Cathepsin B Levels With Blood Pressure and Aortic Dilation., PMID:35425820
A plant-infecting subviral RNA associated with poleroviruses produces a subgenomic RNA which resists exonuclease XRN1 in vitro., PMID:34808564
Development and Validation of a Prognostic Model of RNA-Binding Proteins in Colon Adenocarcinoma: A Study Based on TCGA and GEO Databases., PMID:34675667
Meiotic H3K9me2 distribution is influenced by the ALG-3 and ALG-4 pathway and by poly(U) polymerase activity., PMID:34549171
UTMOST, a single and cross-tissue TWAS (Transcriptome Wide Association Study), reveals new ASD (Autism Spectrum Disorder) associated genes., PMID:33931583
Influenza A virus co-opts ERI1 exonuclease bound to histone mRNA to promote viral transcription., PMID:32960265
Exonuclease requirements for mammalian ribosomal RNA biogenesis and surveillance., PMID:31160785
Role of oligouridylation in normal metabolism and regulated degradation of mammalian histone mRNAs., PMID:30397106
Failure to Replicate an Association of a LINE-1 Element in ERI1 Exoribonuclease Family Member 3 (ERI3) with Schizophrenia., PMID:29123232
Snipper, an Eri1 homologue, affects histone mRNA abundance and is crucial for normal Drosophila melanogaster development., PMID:28626879
Homozygous microdeletion of the ERI1 and MFHAS1 genes in a patient with intellectual disability, limb abnormalities, and cardiac malformation., PMID:28488351
Reserpine requires the D2-type receptor, dop-3, and the exoribonuclease, eri-1, to extend the lifespan in C. elegans., PMID:27966489
Antisense transcription licenses nascent transcripts to mediate transcriptional gene silencing., PMID:27856616
Anti-Ephrin Type-B Receptor 2 (EphB2) and Anti-Three Prime Histone mRNA EXonuclease 1 (THEX1) Autoantibodies in Scleroderma and Lupus., PMID:27617966
ERIL1, the plant homologue of ERI-1, is involved in the processing of chloroplastic rRNAs., PMID:27531275
Tissue homogeneity requires inhibition of unequal gene silencing during development., PMID:27458132
Staufen Negatively Modulates MicroRNA Activity in Caenorhabditis elegans., PMID:26921297
Eri1: a conserved enzyme at the crossroads of multiple RNA-processing pathways., PMID:24929628
Association of plasma ortho-tyrosine/para-tyrosine ratio with responsiveness of erythropoiesis-stimulating agent in dialyzed patients., PMID:24693974
Degradation of oligouridylated histone mRNAs: see UUUUU and goodbye., PMID:24692427
A pre- and co-knockdown of RNAseT enzyme, Eri-1, enhances the efficiency of RNAi induced gene silencing in Caenorhabditis elegans., PMID:24475317
The C-terminal extension of Lsm4 interacts directly with the 3' end of the histone mRNP and is required for efficient histone mRNA degradation., PMID:24255165
Genome-wide screening for components of small interfering RNA (siRNA) and micro-RNA (miRNA) pathways in the brown planthopper, Nilaparvata lugens (Hemiptera: Delphacidae)., PMID:23937246
The nuclear argonaute NRDE-3 contributes to transitive RNAi in Caenorhabditis elegans., PMID:23457236
Structure of histone mRNA stem-loop, human stem-loop binding protein, and 3'hExo ternary complex., PMID:23329046
Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay., PMID:23202588
RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans., PMID:23195953
Identification and functional analysis of the erh1(+) gene encoding enhancer of rudimentary homolog from the fission yeast Schizosaccharomyces pombe., PMID:23145069
Eri1 regulates microRNA homeostasis and mouse lymphocyte development and antiviral function., PMID:22613798
Reduction of mitoferrin results in abnormal development and extended lifespan in Caenorhabditis elegans., PMID:22253756
High-dose siRNAs upregulate mouse Eri-1 at both transcription and posttranscription levels., PMID:22039495
Altered layer-specific gene expression in cortical samples from patients with temporal lobe epilepsy., PMID:21883179
26G endo-siRNAs regulate spermatogenic and zygotic gene expression in Caenorhabditis elegans., PMID:19846761
Requirement for the ERI/DICER complex in endogenous RNA interference and sperm development in Caenorhabditis elegans., PMID:19797044
Caenorhabditis elegans FOS-1 and JUN-1 regulate plc-1 expression in the spermatheca to control ovulation., PMID:19570917
A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in alpha-synuclein transgenic C. elegans., PMID:18617532
The exonuclease ERI-1 has a conserved dual role in 5.8S rRNA processing and RNAi., PMID:18438419
Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing., PMID:18438418
Identification of Caenorhabditis elegans genes regulating longevity using enhanced RNAi-sensitive strains., PMID:18419309
For research use only. Not for human or drug use.
