Catalog No.
YHJ98101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met425-Tyr652
Predicted molecular weight
28.02 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q66K79
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Carboxypeptidase Z, CPZ
Targeting HDAC3 Suppresses Ferroptosis and Demyelination in White Matter Injury by Restoring PDK4-Mediated Iron Homeostasis., PMID:40485011
Significance feature of saffron on testicular histomorphometry and expression profile of antioxidant enzymes in mice with induced multiple sclerosis: an in-vivo study., PMID:40455336
Evodiamine inhibits NLRP3 inflammasome-mediated microglial pyroptosis and promotes remyelination via SLC2A4-regulated autophagy., PMID:40393245
A Colombian strain of Clostridioides difficile ribotype 002 induces a highly inflammatory response in a mouse infection model., PMID:40355394
Ginsenoside Rb3 represses CPZ-induced demyelination and neuroinflammation by inhibiting TRAF6 K63 ubiquitination., PMID:40344978
Chlorpromazine directly inhibits Kv1.3 channels by facilitating the inactivation of channels., PMID:40340862
A novel Wnt/β-catenin signaling gene signature for progression and metastasis of gastric cancer., PMID:40296906
Edaravone protects against cuprizone-induced demyelination in rats by modulating TNF-α/NF-ĸB/NLRP3 signaling and the kynurenine pathway., PMID:40294777
Specific Quenching of Natural Clusterization-Triggered Emission Probes for Rapid Fluorescent Detection of Antipsychotics., PMID:40251124
Alleviation of specific responses in the combined exposure of freshwater mussel Unio tumidus to psychoactive substances and microplastics., PMID:40174756
Baicalin and kaempferol alleviates cuprizone-induced demyelination and microglial activation by inhibiting the STAT3 and NF-κB signaling pathways., PMID:40174341
Acute TREM2 inhibition depletes MAFB-high microglia and hinders remyelination., PMID:40131948
Betaine alleviates deficits in motor behavior, neurotoxic effects, and neuroinflammatory responses in a rat model of demyelination., PMID:40129881
Co-administration of Naringin and NLRP3 Inhibitor Improves Myelin Repair and Mitigates Oxidative Stress in Cuprizone-Induced Demyelination Model., PMID:40123459
G protein-coupled estrogen receptor deficiency exacerbates demyelination through microglial ferroptosis., PMID:39955059
Dual modified ferritin nanocages for tumor-targeted and microenvironment-responsive drug delivery., PMID:39914543
Neuronal TRPV1-CGRP axis regulates peripheral nerve regeneration through ERK/HIF-1 signaling pathway., PMID:39792906
Olig2+ single-colony-derived cranial bone-marrow mesenchymal stem cells achieve improved regeneration in a cuprizone-induced demyelination mouse model., PMID:39743297
The mechanism of exosomes of BMSCs modified with Bu Shen Yi Sui capsule in promoting remyelination via regulating miR-15b/Wnt signaling pathway-mediated differentiation of oligodendrocytes., PMID:39733800
A High-Throughput Method for Screening Peptide Activators of G-Protein-Coupled Receptors., PMID:39676964
Mycoplasma bovis Invades Non-Phagocytic Cells by Clathrin-Dependent Endocytic Pathways and Escapes from Phagocytic Vesicles., PMID:39599557
Curcumin ameliorates astrocyte inflammation through AXL in cuprizone-induced mice., PMID:39586379
Phospholipase D Family Member 4 Regulates Microglial Phagocytosis and Remyelination via the AKT Pathway in a Cuprizone-Induced Multiple Sclerosis Mouse Model., PMID:39548665
Berberine-loaded iron oxide nanoparticles alleviate cuprizone-induced astrocytic reactivity in a rat model of multiple sclerosis., PMID:39543075
The extract from Quzhou Aurantii Fructus attenuates cough variant asthma through inhibiting the TRPV1/Ca2+/NFAT/TSLP pathway and ferroptosis via TRPV1 mediation in ovalbumin-induced mice., PMID:39510426
Transforming growth factor-β1 mediates the beneficial effects of arketamine on demyelination and remyelination in the brains of cuprizone-treated mice., PMID:39500390
Demyelination in cuprizone mice is ameliorated by calycosin mediated through astrocyte Nrf2 signaling pathway., PMID:39489278
In Silico, In Vitro, and In Vivo Studies Indicate the Endocrine-Disrupting Effects of Cyproconazole Stereoisomers., PMID:39465957
The antipsychotic chlorpromazine reduces neuroinflammation by inhibiting microglial voltage-gated potassium channels., PMID:39435609
FOXP3 inhibits proliferation and migration by competitively inhibiting YAP1 in nasopharyngeal carcinoma., PMID:39413576
Pirfenidone mitigates demyelination and electrophysiological alterations in multiple sclerosis: Targeting NF-κB, sirt1, and neurotrophic genes., PMID:39404841
NIR Laser Irradiation Promotes Osteogenic Differentiation of PDLSCs Through the Activation of TRPV1 Channels and Subsequent Calcium Signaling., PMID:39316467
Betaine alleviates cerebellar endoplasmic reticulum stress and oxidative imbalance in a cuprizone model of multiple sclerosis in rat., PMID:39249501
Preventing production of new oligodendrocytes impairs remyelination and sustains behavioural deficits after demyelination., PMID:39213705
Targeting TRPV1 signaling: Galangin improves ethanol-induced gastric mucosal injury., PMID:39047882
Capsaicin alleviates acute alcohol-induced pyroptosis by activating ESCRT-III-dependent cell membrane repair in hepatocytes., PMID:39036891
Association of CSF α-Synuclein Seeding Amplification Assay Results With Clinical Features of Possible and Probable Dementia With Lewy Bodies., PMID:39013126
TRPV1 and mast cell involvement in repeated variate stress-induced urinary bladder dysfunction in adult female mice., PMID:38991005
Galectin-3 alleviates demyelination by modulating microglial anti-inflammatory polarization through PPARγ-CD36 axis., PMID:38986827
High-intensity interval training stimulates remyelination via the Wnt/β-catenin pathway in cuprizone-induced demyelination mouse model., PMID:38979727
A Quantity-Dependent Nonlinear Model of Sodium Cromoglycate Suppression on Beta-Conglycinin Transport., PMID:38928351
ATG10S promotes IFNL1 expression and autophagic degradation of multiple viral proteins mediated by IFNL1., PMID:38842055
Alcohol inducing macrophage M2b polarization in colitis by modulating the TRPV1-MAPK/NF-κB pathways., PMID:38810558
Effective suppression of Ih and INa caused by capsazepine, known to be a blocker of TRPV1 receptor., PMID:38761846
Efflux pump inhibitor chlorpromazine effectively increases the susceptibility of Escherichia coli to antimicrobial peptide Brevinin-2CE., PMID:38683168
The Role of Cannabinoid-1 Receptor Ligands in the Ovalbumin-Induced Mouse Model of Allergic Asthma: Is It Related to Transient Receptor Potential Vanilloid-1 Channels?, PMID:38656908
5Z-7-Oxozaenol attenuates cuprizone-induced demyelination in mice through microglia polarization regulation., PMID:38648385
Engineered protein cages with enhanced extracellular drug release for elevated antitumor efficacy., PMID:38604418
Neuroprotective effects of rutin against cuprizone-induced multiple sclerosis in mice., PMID:38512652
Cannabidiol and it fluorinate analog PECS-101 reduces hyperalgesia and allodynia in trigeminal neuralgia via TRPV1 receptors., PMID:38508408
For research use only. Not for human or drug use.
