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Recombinant Human DNAJC12 Protein, N-His

Catalog #:   YHJ97601 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: Q9UKB3
Protein length: Met1-Lys183
Overview

Catalog No.

YHJ97601

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Met1-Lys183

Predicted molecular weight

23.89 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

Q9UKB3

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

JDP1, J domain-containing protein 1, DnaJ homolog subfamily C member 12, DNAJC12

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human DNAJC12 protein
References

Silencing FGL1 promotes prostate cancer cell apoptosis and inhibits EMT progression., PMID:40481127

Comprehensive analysis of heat shock proteins in glioma revealed the association with glioma-associated myeloid cells., PMID:40234584

Structural recognition and stabilization of tyrosine hydroxylase by the J-domain protein DNAJC12., PMID:40113792

Downregulation of DNAJC12 Expression Predicts Worse Survival for ER-Positive Breast Cancer Patients., PMID:40008192

Impaired cognitive function and decreased monoamine neurotransmitters in the DNAJC12 gene knockout mouse model., PMID:39923104

Exploring the molecular interface of gene expression dynamics and prostate cancer susceptibility in response to HBCD exposure., PMID:39906184

DNAJC12 downregulation induces neuroblastoma progression via increased histone H4K5 lactylation., PMID:39716470

Hyperphenylalaninemia and serotonin deficiency in Dnajc12-deficient mice., PMID:39695187

DNAJC12 Deficiency, an Emerging Condition Picked Up by Newborn Screening: A Case Illustration and a Novel Variant Identified., PMID:39584997

Survival prediction in patients with head and neck squamous cell carcinoma and novel mechanistic insights of S100A8/A9., PMID:39546127

Characterization of Dnajc12 knockout mice, a model of hypodopaminergia., PMID:39026821

Age-dependent functional development pattern in neonatal brain: An fMRI-based brain entropy study., PMID:38852805

PAH deficient pathology in humanized c.1066-11G>A phenylketonuria mice., PMID:38520741

DNAJC12 causes breast cancer chemotherapy resistance by repressing doxorubicin-induced ferroptosis and apoptosis via activation of AKT., PMID:38306757

DNAJC12 deficiency: Mild hyperphenylalaninemia and neurological impairment in two siblings., PMID:38053929

DNAJC12 in Monoamine Metabolism, Neurodevelopment, and Neurodegeneration., PMID:38014588

A rare cause of hyperphenylalaninemia: four cases from a single family with DNAJC12 deficiency., PMID:37283250

Developmental delay and non-phenylketonuria (PKU) hyperphenylalaninemia in DNAJC12 deficiency: Case and approach., PMID:37156708

Identification of two novel DNAJC12 gene variants in a patient with mild hyperphenylalaninemia., PMID:36990253

Restless legs syndrome in DNAJC12 deficiency., PMID:36897462

Clinical, genetic, and experimental research of hyperphenylalaninemia., PMID:36685931

Inhibition of DNAJC12 Inhibited Tumorigenesis of Rectal Cancer via Downregulating HSPA4 Expression., PMID:36185081

DNAJC12 activated by HNF1A enhances aerobic glycolysis and drug resistance in non-small cell lung cancer., PMID:35571408

DNACJ12 deficiency in patients with unexplained hyperphenylalaninemia: two new patients and a novel variant., PMID:34014443

DNAJC12 promotes lung cancer growth by regulating the activation of β‑catenin., PMID:33907820

Genetic Dystonias: Update on Classification and New Genetic Discoveries., PMID:33564903

Phenylalanine and tyrosine metabolism in DNAJC12 deficiency: A comparison between inherited hyperphenylalaninemias and healthy subjects., PMID:32800687

Two novel mutations in DNAJC12 identified by whole-exome sequencing in a patient with mild hyperphenylalaninemia., PMID:32519510

Network Analyses of the Differential Expression of Heat Shock Proteins in Glioma., PMID:32429692

Pathogenic variants of DNAJC12 and evaluation of the encoded cochaperone as a genetic modifier of hyperphenylalaninemia., PMID:32333439

Analysis of Catecholamines and Pterins in Inborn Errors of Monoamine Neurotransmitter Metabolism-From Past to Future., PMID:31405045

Major depressive disorder-associated SIRT1 locus affects the risk for suicide in women after middle age., PMID:31176830

DNAJC proteins and pathways to parkinsonism., PMID:31120186

Generation of 2 iPSC clones from a patient with DNAJC12 deficiency: DHMCi003-A and DHMCi003-B., PMID:30901742

Phenylalanine hydroxylase variants interact with the co-chaperone DNAJC12., PMID:30667134

Increased Expression of DNAJC12 is Associated with Aggressive Phenotype of Gastric Cancer., PMID:30617870

Identification of an inherited pathogenic DNAJC12 variant in a patient with hyperphenylalalinemia., PMID:30179615

DNAJC12-associated developmental delay, movement disorder, and mild hyperphenylalaninemia identified by whole-exome sequencing re-analysis., PMID:30139987

RNA sequencing reveals upregulation of a transcriptomic program associated with stemness in metastatic prostate cancer cells selected for taxane resistance., PMID:30100995

Understanding the regulatory mechanisms of milk production using integrative transcriptomic and proteomic analyses: improving inefficient utilization of crop by-products as forage in dairy industry., PMID:29843597

DNAJC12 mutation is rare in Chinese Han population with Parkinson's disease., PMID:29801756

DNAJC12: A molecular chaperone involved in proteostasis, PKU, biogenic amines metabolism and beyond?, PMID:29396030

DNAJC12 deficiency: A new strategy in the diagnosis of hyperphenylalaninemias., PMID:29174366

DNAJC12 and dopa-responsive nonprogressive parkinsonism., PMID:28892570

Heterogeneous clinical spectrum of DNAJC12-deficient hyperphenylalaninemia: from attention deficit to severe dystonia and intellectual disability., PMID:28794131

Biallelic Mutations in DNAJC12 Cause Hyperphenylalaninemia, Dystonia, and Intellectual Disability., PMID:28132689

Overexpression of DNAJC12 predicts poor response to neoadjuvant concurrent chemoradiotherapy in patients with rectal cancer., PMID:25805104

The co-chaperone DNAJC12 binds to Hsc70 and is upregulated by endoplasmic reticulum stress., PMID:24122553

Hypermethylation of TUSC5 genes in breast cancer tissue., PMID:23302999

Tamoxifen downregulates ets oncogene family members ETV4 and ETV5 in benign breast tissue: implications for durable risk reduction., PMID:21778330

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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Recombinant Human DNAJC12 Protein, N-His [YHJ97601]
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