Catalog No.
YHJ81901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly21-Cys145
Predicted molecular weight
16.85 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UNK4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PLA2IID, SPLASH, Group IID secretory phospholipase A2, sPLA2-IID, Secretory-type PLA, stroma-associated homolog, GIID sPLA2, Phosphatidylcholine 2-acylhydrolase 2D, PLA2G2D
Mult-omics analysis reveals the lipid-lowering effects of sea buckthorn and milk thistle solid beverage in hyperlipidemic rats., PMID:40472616
GJB2 as a novel prognostic biomarker associated with immune infiltration and cuproptosis in ovarian cancer., PMID:40375037
Bioinformatics analysis reveals novel tumor antigens and immune subtypes of skin cutaneous melanoma contributing to mRNA vaccine development., PMID:40066453
AnGong NiuHuang (AGNH) pill attenuated traumatic brain injury through regulating NF-κB/Nlrp3 axis and glycerophospholipid metabolism., PMID:38936259
Obesity enhances the response to neoadjuvant anti-PD1 therapy in oral tongue squamous cell carcinoma., PMID:38923758
PLA2G2D promotes immune escape in non-small cell lung cancer by regulating T cell immune function through PD-L1-expressing extracellular vesicles., PMID:38922971
Screening of Lipid Metabolism-Related Genes as Diagnostic Indicators in Chronic Obstructive Pulmonary Disease., PMID:38046983
Deep phenotyping of the lipidomic response in COVID-19 and non-COVID-19 sepsis., PMID:37948331
The coexistence of aflatoxin M1 and ochratoxin A induced intestinal barrier disruption via the regulation of key differentially expressed microRNAs and long non-coding RNAs in BALB/c mice., PMID:37688864
Identification and immunological characterization of PLA2G2A and cell death-associated molecular clusters in idiopathic pulmonary fibrosis., PMID:37673297
Identification of genetic mechanisms underlying lipid metabolism-mediated tumor immunity in head and neck squamous cell carcinoma., PMID:37210507
Development of a metabolism-related signature for predicting prognosis, immune infiltration and immunotherapy response in breast cancer., PMID:36628282
A Metabolism-Related Gene Prognostic Index Bridging Metabolic Signatures and Antitumor Immune Cycling in Head and Neck Squamous Cell Carcinoma., PMID:35844514
The Metabolic Signature of AML Cells Treated With Homoharringtonine., PMID:35774129
Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19., PMID:35314834
Anatomical Transcriptome Atlas of the Male Mouse Reproductive System During Aging., PMID:35211476
Tumor Immune Microenvironment Related Gene-Based Model to Predict Prognosis and Response to Compounds in Ovarian Cancer., PMID:34966691
Metabolic Molecule PLA2G2D Is a Potential Prognostic Biomarker Correlating With Immune Cell Infiltration and the Expression of Immune Checkpoint Genes in Cervical Squamous Cell Carcinoma., PMID:34733790
Transcription profiling of cadmium-exposed livers reveals alteration of lipid metabolism and predisposition to hepatic steatosis., PMID:34696656
Low CCL19 expression is associated with adverse clinical outcomes for follicular lymphoma patients treated with chemoimmunotherapy., PMID:34544443
Development of a Novel Immune Infiltration-Based Gene Signature to Predict Prognosis and Immunotherapy Response of Patients With Cervical Cancer., PMID:34539641
Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity., PMID:34446728
Coronavirus-specific antibody production in middle-aged mice requires phospholipase A2G2D., PMID:34060490
Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19., PMID:33907749
Identification of Metabolic-Associated Genes for the Prediction of Colon and Rectal Adenocarcinoma., PMID:33833525
Dysregulation of endocannabinoid concentrations in human subcutaneous adipose tissue in obesity and modulation by omega-3 polyunsaturated fatty acids., PMID:33393630
Secreted Phospholipase PLA2G2D Contributes to Metabolic Health by Mobilizing ω3 Polyunsaturated Fatty Acids in WAT., PMID:32375030
Meta-Analysis of Pulmonary Transcriptomes from Differently Primed Mice Identifies Molecular Signatures to Differentiate Immune Responses following Bordetella pertussis Challenge., PMID:28243609
The Spleen Is an Ideal Site for Inducing Transplanted Islet Graft Expansion in Mice., PMID:28135283
Differential Expression of Inflammation-Related Genes in Children with Down Syndrome., PMID:27293319
Dual Roles of Group IID Phospholipase A2 in Inflammation and Cancer., PMID:27226632
Critical role of phospholipase A2 group IID in age-related susceptibility to severe acute respiratory syndrome-CoV infection., PMID:26392224
Association between polymorphisms in phospholipase A2 genes and the plasma triglyceride response to an n-3 PUFA supplementation: a clinical trial., PMID:25889305
Nonbactericidal secreted phospholipase A2s are potential anti-inflammatory factors in the mammary gland., PMID:24091988
Lymphoid tissue phospholipase A2 group IID resolves contact hypersensitivity by driving antiinflammatory lipid mediators., PMID:23690440
Effect of allergy and inflammation on eicosanoid gene expression in CFTR deficiency., PMID:22985691
Expression profile of proinflammatory genes in neutrophil-enriched granulocytes stimulated with native anti-PR3 autoantibodies., PMID:22791638
The P2Y2/Src/p38/COX-2 pathway is involved in the resistance to ursolic acid-induced apoptosis in colorectal and prostate cancer cells., PMID:22521508
Secretory phospholipase A2 group IID Is involved in progesterone-induced acrosomal exocytosis of human spermatozoa., PMID:22240557
Gly80Ser polymorphism of phospholipase A2-IID is associated with cytokine inducibility in A549 cells., PMID:19365107
Distinct expression pattern of the full set of secreted phospholipases A2 in human colorectal adenocarcinomas: sPLA2-III as a biomarker candidate., PMID:18212756
Exploration of associations between phospholipase A2 gene family polymorphisms and AIDS progression using the SNPlex method., PMID:18096355
Tagging SNP haplotype analysis of the secretory PLA2-V gene, PLA2G5, shows strong association with LDL and oxLDL levels, suggesting functional distinction from sPLA2-IIA: results from the UDACS study., PMID:17545304
Inhibition of secreted phospholipase A2. 4-glycerol derivatives of 4,5-dihydro-3-(4-tetradecyloxybenzyl)-1,2,4-4H-oxadiazol-5-one with broad activities., PMID:17335183
Accelerated expansion of group IID-like phospholipase A2 genes in Bos taurus., PMID:16469480
Diverse cellular localizations of secretory phospholipase A2 enzymes in several human tissues., PMID:16188494
Inhibition of secretory phospholipase A2. 1-design, synthesis and structure-activity relationship studies starting from 4-tetradecyloxybenzamidine to obtain specific inhibitors of group II sPLA2s., PMID:16084626
A novel polymorphism in secretory phospholipase A2-IID is associated with body weight loss in chronic obstructive pulmonary disease., PMID:16002569
Bactericidal properties of human and murine groups I, II, V, X, and XII secreted phospholipases A(2)., PMID:11694541
SPLASH (PLA2IID), a novel member of phospholipase A2 family, is associated with lymphotoxin deficiency., PMID:11196711
For research use only. Not for human or drug use.
