Catalog No.
YHJ69801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile30-Lys511
Predicted molecular weight
58.22 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NZK5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Adenosine deaminase 2, IDGFL, ADGF, ADA2, Cat eye syndrome critical region protein 1, CECR1
Probing Enzymatic Acetylation Events in Real Time With NMR Spectroscopy: Insights Into Acyl-Cofactor Dependent p300 Modification of Histone H4., PMID:40452297
Nailfold videocapillaroscopy in patients with deficiency of adenosine deaminase 2 (DADA2): a case-control study., PMID:40410857
Novel Link Between Myeloid-Specific Adenosine Deaminase 2 and CXCL10-CXCR3 Axis in Infectious ARDS., PMID:40332245
[ADA2, an Adenosine Deaminase Isozyme Acting as a Regulator of Autoinflammation]., PMID:40307021
Mimics and challenging presentations of DADA2., PMID:40117338
Deficiency of Adenosine Deaminase 2 Masquerading as Behçet's Disease: Phenotypic Mimicry with HLA-B*51 Positivity., PMID:40097865
Infantile Pure Red Cell Aplasia Secondary to Deficiency of Adenosine Deaminase2 (DADA2) Syndrome-Time to Think Beyond Diamond Blackfan Anemia., PMID:40095445
Getting to know adenosine deaminase 2 deficiency inside and out., PMID:39956283
Sequential central retinal artery occlusion in two brothers: a fight to prevent blindness., PMID:39934596
Deficiency of adenosine deaminase 2 skews adaptive immune repertoires toward specific sets of T- and B-cell receptors., PMID:39924119
Immunodeficiency in children with Diamond Blackfan and Diamond Blackfan like anemia., PMID:39923319
Intracellular concentration of ADA2 is a marker for monocyte differentiation and activation., PMID:39832022
Central nervous system vasculopathy: inherited or acquired? The DADA2 conundrum., PMID:39778928
Dominant negative ADA2 mutations cause ADA2 deficiency in heterozygous carriers., PMID:39711711
Bilateral cataracts in a three-year-old with deficiency of adenosine deaminase 2 (DADA2), hyperferritinemia, and prolonged steroid use., PMID:39530311
Carrier frequency and incidence estimation of deficiency of adenosine deaminase 2 in the Chinese population based on massive exome sequencing data., PMID:39481740
ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA., PMID:39441717
Plasma adenosine deaminase-1 and -2 activities are lower at birth in Papua New Guinea than in The Gambia but converge over the first weeks of life., PMID:39386208
Rare primary vasculitis: update on multiple complex diseases and the new kids on the block., PMID:39385260
Overexpression of GmSRC2 confers resistance to Phytophthora sojae in soybean., PMID:39313002
Early bone marrow alterations in patients with adenosine deaminase 2 deficiency across disease phenotypes and severities., PMID:39284370
Clinical spectrum of and outcomes for Indian children with deficiency of adenosine deaminase 2 (DADA2): a multicentric study., PMID:39259214
Deficiency of Adenosine Deaminase 2., PMID:39120005
Adenosine deaminase 2 regulates the activation of the toll-like receptor 9 in response to nucleic acids., PMID:39078537
Genetic Testing in Patients with Autoimmune Lymphoproliferative Syndrome: Experience of 802 Patients at Cincinnati Children's Hospital Medical Center., PMID:39060684
Human ADA2 Deficiency: Ten Years Later., PMID:38970744
DADA2 deficiency caused by new homozygous variation in 22q11.1., PMID:38910582
Salivary biomarkers as pioneering indicators for diagnosis and severity stratification of pediatric long COVID., PMID:38881733
A pilot study of childhood-onset Takayasu arteritis using whole exome sequencing suggests oligogenic inheritance involving classical complement, collagen, and autoinflammatory pathways., PMID:38869681
Deficiency of adenosine deaminase 2 (DADA2) presenting with diffuse skeletal muscle vasculitis., PMID:38804661
ADA2 regulates inflammation and hematopoietic stem cell emergence via the A2bR pathway in zebrafish., PMID:38777862
Development of EBV Related Diffuse Large B-cell Lymphoma in Deficiency of Adenosine Deaminase 2 with Uncontrolled EBV Infection., PMID:38758417
Deficiency of adenosine deaminase 2: a genetic autoinflammatory disorder mimicking childhood polyarteritis nodosa., PMID:38724212
Central retinal artery occlusion in a child with ADA2 deficiency: a case report., PMID:38576931
ADA-2 gene mutation in a Crohn's disease patient without response to therapy., PMID:38554426
Integrated plasma proteomics identifies tuberculosis-specific diagnostic biomarkers., PMID:38512356
A case report on deficiency of adenosine deaminase 2 with relapse-remission course and analysis of genotype-phenotype correlation., PMID:38353426
Lysine acetylation of histone acetyltransferase adaptor protein ADA2 is a mechanism of metabolic control of chromatin modification in plants., PMID:38326652
Optimizing rice grain size by attenuating phosphorylation-triggered functional impairment of a chromatin modifier ternary complex., PMID:38237589
Proposal for a Disease Activity Score and Disease Damage Score for ADA2 Deficiency: the DADA2AI and DADA2DI., PMID:38129740
Sudden unexpected death of a young adult due to subarachnoid hemorrhage associated with polyarteritis nodosa: Clinicopathological appearance and literature review., PMID:38072093
The Diverse Genomic Landscape of Diamond-Blackfan Anemia: Two Novel Variants and a Mini-Review., PMID:38002903
Deubiquitination module is critical for oxidative stress response and biofilm formation in Candida glabrata., PMID:37844959
Selective ADA2 inhibition for enhancing anti-tumor immune response in glioma: Insights from computational screening of flavonoid compounds., PMID:37844820
Regulation of fungal raw-starch-degrading enzyme production depends on transcription factor phosphorylation and recruitment of the Mediator complex., PMID:37828083
Deficiency of Adenosine Deaminase 2: Clinical Manifestations, Diagnosis, and Treatment., PMID:37821195
A whole genome scan reveals distinct features of selection in Zhaotong cattle of Yunnan province., PMID:37796667
Novel ADA2 Variants in a Romanian Case Series of DADA2., PMID:37783985
Vasculitis associated with adenosine deaminase 2 deficiency: at the crossroads between Behçet's disease and autoinflammation. A viewpoint., PMID:37721348
Changes in Adenosine Deaminase Activity and Endothelial Dysfunction after Mild Coronavirus Disease-2019., PMID:37685949
For research use only. Not for human or drug use.
